CAS: 27631-29-4; 2,4-Dichloro-6,7-Dimethoxyquinazoline

上下游产品

CAS号28888-44-0 6,7-二甲氧基-2,4-喹唑啉二酮 | CAS号32315-10-9 三光气 | CAS号26961-27-3 2-氨基-4,5-二甲氧基苯腈 | CAS号2150-38-1 3,4-二甲氧基苯甲酸甲酯 | CAS号26791-93-5 4,5-二甲氧基-2-硝基苯甲酸甲酯 | CAS号5653-40-7 2-氨基-4,5-二甲氧基苯甲酸 | CAS号26759-46-6 2-氨基-4,5-二甲氧基苯甲酸甲酯 | CAS号4998-07-6 4,5-二甲氧基-2-硝基苯甲酸 | CAS号4959-60-8 4,5-二甲氧基-2-硝基苯甲酰胺 | CAS号5004-88-6 2-氨基-4,5-二甲氧基苯甲酰胺 | CAS号111218-76-9 1-((2-Chloro-6,... | CAS号94644-47-0 2-氯-6,7-二甲氧基喹唑啉 | CAS号20197-86-8 2-氯-6,7-二甲氧基-1H... | CAS号23680-84-4 4-氨基-2-氯-6, 7-二氧基喹唑啉 | CAS号134749-25-0 1-[6,7-dimethox... | CAS号134749-28-3 [[2-(diethylami... | CAS号134749-40-9 1-[[2-(diethyla... | CAS号134749-35-2 [[2-(ethylamino... | CAS号134749-32-9 [[2-(2-aminoeth... | CAS号134749-33-0 [[6,7-dimethoxy...

5,6-Dimethoxy-Indoline-2,3-Dione-3-Oxime置于三光气,Tris(4-Methoxyphenyl)Phosphine Oxide体系中,用 氯苯 用作溶剂,化学反应 4.0H,以92%的收率获得2,4-二氯-6,7-二甲氧基喹唑啉
参考文献:由双(三氯甲基)碳酸酯和三芳基氧化膦介导的靛红-3-肟一锅级联环扩大为 2,4-二氯喹唑啉
标题:由双(三氯甲基)碳酸酯和三芳基氧化膦介导的靛红-3-肟一锅级联环扩大为 2,4-二氯喹唑啉
摘要:摘要 开发了一种直接从靛红-3-肟与双(三氯甲基)碳酸酯和三芳基膦氧化物直接高效,方便地一锅级联合成 2,4-二氯喹唑啉的方法,以中等至优异的收率获得取代的喹唑啉.与一系列官能团的兼容性证明了这种转化的效率.因此,该方法代表了合成取代的 2,4-二氯喹唑啉的一种方便实用的策略.图形概要
Doi:10.1080/10426507.2020.1782910

专利信息

专利号:WO-0168615-A1
优先权日:2000-03-13
标题 :Quinazoline synthesis
发明人：DENER JEFFREY MARK; LEASE TIMOTHY G; NOVACK AARON ROBERT
权利人:CHEMRX ADVANCED TECHNOLOGIES I; DENER JEFFREY MARK; LEASE TIMOTHY G; NOVACK AARON ROBERT
摘要:The present invention relates to a method for making a compound of Formulas I, II and III. The method of the present invention also enables parallel and simultaneous synthesis of a plurality of compounds represented by Formulas I, II and III.

专利号:US-8895747-B2
优先权日:2009-07-27
标 题 :Method and substances for preparation of N-substituted pyridinium compounds
发明人：HEINDL DIETER; MAERZ HERIBERT; SCHMIDT AXEL
权利人:HEINDL DIETER; MAERZ HERIBERT; SCHMIDT AXEL; ROCHE DIAGNOSTICS OPERATIONS
摘要:Methods for the synthesis of N-substituted pyridinium compounds by using an N-heteroaryl substituted pyridinium salt (Zincke salt) and reacting it with a nucleophilic amine are provided. Novel purine-substituted pyridyl compounds, which may be useful reagents in the above reaction, are also disclosed.

专利号:US-2008039473-A1
优先权日:2006-08-08
标题:Preparation and utility of substituted quinazoline compounds with alpha-adrenergic blocking effects
发明人：GANT THOMAS G; SARSHAR SEPEHR
权利人:AUSPEX PHARMACEUTICALS INC
摘要:The present disclosure is directed to modulators of alpha-adrenergic receptors and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the use of such compounds for the treatment and/or management of hypertension, cardiac failure, prostatitis, and benign prostatic hyperplasia, and any other condition in which it is beneficial to modulate an alpha-adrenergic receptor.

专利号:EP-1370552-B1
优先权日:2001-03-23
标题:Rho-kinase inhibitors
发明人：NAGARATHNAM DHANAPALAN; WANG CHUNGUANG
权利人:BAYER PHARMACEUTICALS CORP
摘要:Disclosed are compounds and derivatives thereof, their synthesis, and their use as Rho-kinase inhibitors. These compounds of the present invention are useful for inhibiting tumor growth, treating erectile dysfunction, and treating other indications mediated by Rho-kinase, e.g., coronary heart disease.