CAS: 2160-89-6; 1,1,1,3,3,3-Hexafluoropropan-2-Yl Acrylate

上下游产品

1,1,1,3',3',3'-hexafluoro-propanol acryloyl chloride 1,1,1,3,3,3-hexafluoropropan-2-yl (R)-3-hydroxy-2-methylene-3-phenylpropanoate 1,1,1,3,3,3-hexafluoropropan-2-yl (R)-3-cyclohexyl-3-hydroxy-2-methylenepropanoate methyl (S)-2-methanesulfonylamino-2-phenylacetate

六氟异丙醇,丙烯酰氯置于三乙胺体系中,用 二氯甲烷 用作溶剂,化学反应生成1,1,1,3,3,3-六氟异丙基丙烯酸酯
参考文献:铱(III)催化的β-三氟亚甲基烯酮羰基定向区域选择性邻-C(Sp2)-h烯化
标题:铱(III)催化的β-三氟亚甲基烯酮羰基定向区域选择性邻-C(Sp2)-h烯化
摘要:由于α,β-不饱和-β-三氟亚甲基酮的β位lumo能级低于其非氟化对应物,因此激活芳环的sp 2 C-H键存在挑战.在此,我们报道了氧化条件下铱( Iii )催化的β-三氟亚甲基烯酮羰基定向芳香族c(Sp 2 )-h与丙烯酸酯的区域选择性烯化反应.此外,还进行了与天然产物丙烯酸酯的偶联,放大和产品多样化.
Doi:10.1039/d3Ob02024J

专利信息

专利号:US-10465033-B2
优先权日:2016-11-10
标题:One step synthesis of ultrahigh molecular weight block copolymers
发明人：URBAN MAREK W
权利人:UNIV CLEMSON; UNIV CLEMSON RES FOUNDATION
摘要:Single-step synthesis processes for production of ultrahigh molecular weight block copolymers are described. The ultrahigh molecular weight copolymers can have a molecular weight of about 10 6 or greater and can be formed within a few hours in a surfactant-free environment. The formation process is controlled by initiator-starvation conditions in a sequential polymerization of monomers exhibiting different solubility in the solvent.

专利号:US-9512250-B2
优先权日:2012-02-23
标 题 :Manganese catalyzed photopolymerization of fluorinated monomers
发明人：ASANDEI ALEXANDRU D
权利人:UNIV CONNECTICUT
摘要:The disclosure discloses initiating systems for the radical polymerization of alkenes, and especially fluorine substituted alkenes. The polymerization is catalyzed by a metal carbonyl, preferably manganese carbonyl. The polymerization is initiated directly from alkyl halides at room temperature under visible white light. The polymers also allow the synthesis of block copolymers. The process comprises polymerizing at least one alkene monomer in the presence of a halide radical initiator, carbonyl catalyst and a solvent, under reaction conditions and for a time sufficient to polymerize the at least one alkene monomer to form a polymer. The present disclosure provides a method for living polymerization of alkene monomers which provides a high level of macromolecular control over the polymerization process and which leads to uniform and controllable polymeric products. This disclosure also provides a method for activating any halide (Cl, Br, I) chain ends of such polymers for the synthesis of block copolymerizations.

专利号:EP-2647639-A1
优先权日:2012-04-06
标题:ß-boration of alkene and alkyne intermediates
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic chemistry, and in particular to the preparation of β-borated compounds. These β-borated compounds can be used as intermediates in the synthesis of pharmaceutically active agents such as Sitagliptin.

专利号:US-8053161-B2
优先权日:2006-09-25
标 题 :Resist composition, resin for use in the resist composition, compound for use in the synthesis of the resin, and pattern-forming method using the resist composition
发明人：WADA KENJI; SAEGUSA HIROSHI
权利人:FUJIFILM CORP
摘要:A resist composition comprises: (A) a resin capable of increasing its solubility in an alkali developer by action of an acid; (B) a compound capable of generating an acid upon irradiation with actinic ray or radiation; (C) a resin having at least one of a fluorine atom and a silicon atom; and (D) a solvent, wherein the resin (C) has a degree of molecular weight dispersion of 1.3 or less and a weight average molecular weight of 1.0×10 4 or less.

专利号:EP-2647640-A1
优先权日:2012-04-06
标 题:ß-boration of alkene and alkyne intermediates
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic chemistry, and in particular to the preparation of β-borated compounds. These β-boated compounds can be used as intermediates in the synthesis of pharmaceutically active agents such as Sitagliptin.

专利号:US-7902196-B2
优先权日:2005-03-17
标 题 :Synthesis of avrainvillamide, strephacidin B, and analogues thereof
发明人：MYERS ANDREW G; HERZON SETH B; WULFF JEREMY EARLE; SIEGRIST ROMAIN; SVENDA JAKUB; ZAJAC MATTHEW ALLEN
权利人:HARVARD COLLEGE
摘要:The syntheses of the natural products, avrainvillamide and stephacidin B, are provided. The α,β-unsaturated nitrone functionality of avrainvillamide and its 3-alkylidene-3H-indole 1-oxide core is shown to covalently and reversibly bond to heteroatom-based nucleophiles. This capability may allow these molecules to bind active site nucleophiles and may provide the basis for designing potent and selective enzyme inhibitors. Both avrainvillamide and its dimer stephacidin B have been reported to exhibit antiproliferative activity, and avrainvillamide has been reported to exhibit antimicrobial activity against multi-drug resistant bacteria. Avrainvillamide has been found to target cytoskeleton-linking membrane protein (CLIMP-63) thereby preventing cells from undergoing mitosis. The invention provides syntheses of these natural products as well as analogs of these natural products and their functional cores. The compounds of the invention may be used in the treatment of diseases such as cancer, autoimmune diseases, and bacterial infection.