- 英文名称1H-Indole-5-Sulfonic Acid, 2-(1,3-Dihydro-3-Oxo-5-Sulfo-2H-Indol-2-Ylidene)-2,3-Dihydro-3-Oxo-, Potassium Salt (1:2)
- 中文名称靛蓝二磺酸二钾盐
- IUPAC名称potassium 3,3'-dioxo-[2,2'-biindolinylidene]-5,5'-disulfonate
- 其它别名Indigodisulfonate Dipotassium Salt; Indigodisulfonic Acid Dipotassium Salt; Indigodisulfonic Acid, K Salt; 3,3'-Dioxo[δ2,2'-Biindoline]-5,5'-Disulfonic Acid Dipotassium Salt; Indigodisulfonicaciddipotassiumsalt>1H-Indole-5-Sulfonic Acid, 2-(1,3-Dihydro-3-Oxo-5-Sulfo-2H-Indol-2-Ylidene)-2,3-Dihydro-3-Oxo-, Potassium Salt (1:2); Indigodisulfonicaciddipotassiumsal; Potassium (E)-3,3′-Dioxo-[2,2′-Biindolinylidene]-5,5′-Disulfonate
- CAS编号13725-33-2
- MFCD编号:MFCD00067311
- 分子式:C16H8K2N2O8S2分子量:498.58
- 产品CID: 579054
- 产品分类化学试剂 → 有机试剂 → 磺酸盐/亚磺酸盐
- 相似结构搜索
- InChIKey: PLXHLMUZUKUFAR-QDBORUFSSA-L
- InChI=1S/C16H10N2O8S2.2K/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2
- 计算化学: 氢键受体数9.0氢键供体数2.0可旋转键数1.0
海关参考信息
- 2902600000-乙苯
2912110000-甲醛
2912120000-乙醛
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专利信息
专利号:WO-2024097977-A1
优先权日:2022-11-04
标题:Silk nanoparticle synthesis: tuning size, dispersity, and surface chemistry for drug delivery
发明人:SHAIDANI SAWNAZ; FALCUCCI THOMAS; FOSTER OLIVIA; SAHOO JUGAL KISHORE; HASTURK ONUR; KAPLAN DAVID L; JACOBUS CHARLOTTE S
权利人:TUFTS COLLEGE
摘要:Methods disclosed herein relate to generating silk nanoparticles with a low polydispersity index (PDI). Methods include adding a silk solution dropwise into a volatile solvent that is miscible with water, thereby forming a precipitate-bearing solution and applying shear forces to the precipitate-bearing solution for a length of time sufficient to achieve evaporation of at least 95% of the volatile solvent, thereby producing a population of silk fibroin nanoparticles in water having a polydispersity index (PDI) of 0.35 or less, including but not limited to, a PDI of 0.330 or less, 0.325 or less, 0.315 or less, 0.310 or less, 0.30 or less, 0.275 or less, 0.250 or less, 0.225 or less, or 0.200 or less. Parameters related to silk fibroin molecular weight, silk fibroin concentration, shear force application, and temperature may all be modified to achieve silk nanoparticles of a particular size exhibiting particular PDIs.