CAS: 768-05-8; Pyrazinoic Acid Hydrazide

该化合物是有机化合物,其特点是其双子氨环结构,这是一个由六人组成的芳香环,内含两个氮原子.该化合物的特点是一种氢氮化功能组,该组是来自九子和一碳酸的反应.它一般是白色到白色的晶体固体,在极地溶剂中溶解.青子和氢氮的两种功能的存在都有助于其潜在的生物活动,因此引起药物研究的兴趣.该化合物可能具有抗微生物或抗氟化作用等特性,尽管具体的生物活动可能各不相同.其分子结构允许各种化学反应,使其成为有机合成的多种中间体.应当参考安全数据,以便处理和使用,如同任何化学物质一样,确保采取适当的预防措施.

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98-96-4 135691-54-2 41110-27-4

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    专利信息


    专利号:US-2024335442-A1
    优先权日:2021-08-02
    标 题:N-acylhydrazone compounds capable of inhibiting nav1.7 and/or nav1.8, processes for the preparation thereof, compositions, uses, methods for treatment using same, and kits
    发明人：BARREIRO GABRIELA; SANT'ANA DANILO PEREIRA DE; GAMBA LUIS EDUARDO REINA; FRAGA CARLOS ALBERTO MANSSOUR; BARREIRO ELIEZER JESUS DE LACERDA; LIMA LÃ?DIA MOREIRA
    权利人:EUROFARMA LABORATORIOS S A; UNIV FEDERAL DO RIO DE JANEIRO UFRJ
    摘要:N-acylhydrazone compounds that are Nav 1.7 and/or Nav 1.8 inhibitors, including N-acylhydrazone compounds of Formula (I), wherein the substituents R1 to R6 are independently selected from the groups defined in the specification, as well as to the processes for the preparation thereof, compositions comprising at least one of said compounds, uses, treatment methods for treating or preventing pain-related pathologies, and kits, and which are applicable in the fields of medicinal chemistry and organic synthesis, as well as in the treatment of pain-related disorders.

    专利号:CN-114835656-A
    优先权日:2022-05-13
    标 题:A kind of ethyl 1,3,4-oxadiazole acetate and its synthesis method

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    合成参考文献


    摘要:Blakemore, P. R., Science of Synthesis, (2005) 21, 891.
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