CAS: 7283-09-2; (2R,3R,4R,5S,6R)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2,3,4,5-Tetraol

该化合物是六种六人环状甘蔗环状环状,是一种光化糖.它的特征是其环状结构,有五种碳原子和一个氧原子组成环状. 亚麻鼠表示,亚马逊碳(C1)的氢氧基体组位于环形上方,这是其立体化学特征的一个特征. 这个化合物是水中溶解的白晶状固体,反映了其多氢化(-OH)组的极性. -D-Aloperanose在各种生物化学过程中发挥作用,可以参与合成玻璃表面和其他碳水化合物衍生物. 它的甜度和再活性使其对食物化学和生物化学具有兴趣. 此外,它可以参与对多元石化结构至关重要的石化结合形成. 与许多糖一样,它可以发生突变,导致蛋状之间的平衡.

结构式图片

相似化合物

10257-28-0 530-26-7 492-66-0

上下游产品

formaldehydephenlyl-O-β-D-pyranosyl allosideD-allose 6-O-laurate gluconolactone

合成工艺路线路线简述

  • 合成目标产物 Beta-D-Allose 主要起始原料 Helicid
  • (文献来源)合成步骤主要原料 Helicid
📜A-无水葡萄糖酯置于sodium Tetrahydroborate,[(2,9-Dimethyl-1,10-Phenanthroline)-Pd(μ-Oac)]2(Otf)2,对苯醌体系中,用 水,二甲基亚砜 作为反应溶剂,化学反应 2.0H,反应生成 β-D-别吡喃糖
参考文献:通过区域选择性氧化和还原作用,C3葡萄糖的差向异构
标题:通过区域选择性氧化和还原作用,C3葡萄糖的差向异构
摘要:钯催化的氧化可以选出葡萄糖中c3处的仲羟基,从而避开了c6处更容易接近的羟基和反应性更高的异头羟基.氧化然后还原导致异位糖或异丁醇,每一种都是在生物技术中很重要的稀有糖.同样,N-乙酰氨基葡糖在c3处被选择性地氧化.这些结果表明,葡萄糖和n-乙酰氨基葡糖是最容易获得的手性结构单元,在均相催化中可以是通用底物.
DOI:10.1021/acs.Joc.6B02074

海关参考信息

专利信息


专利号:US-2022395800-A1
优先权日:2019-11-04
标题:Device for automated synthesis of oligo- and polysaccharides
发明人:SEEBERGER PETER H; DANGLAD FLORES JOSE; LE MAI HOANG KIM; PARDO VARGAS ALONSO; SLETTEN ERIC; SALWICZEK MARIO
权利人:MAX PLANCK GESELLSCHAT ZU RFERDERUNG DER WSS E V; GlycoUniverse GmbH & Co KG&A
摘要:The present invention generally relates to automated synthesis technology, and more particularly, to a device and method for automated synthesis of oligo- and polysaccharides on a solid support. In particular the present invention relates to a device for automated synthesis of oligo- and polysaccharides on a solid support comprising a reaction vessel, a reagent storing component, a reagent delivery system, a cooling device for cooling reaction vessel, and a pre-cooling device for pre-cooling the reagents to be supplied.

专利号:EP-3835306-A1
优先权日:2019-12-13
标题:Microwave-assisted method for synthesis of oligo- and polysaccharides on solid phase
权利人:MAX PLANCK GESELLSCHAFT
摘要:The present invention relates to a method for synthesizing oligo- and polysaccharides using microwave radiation, in particular to a method and a device for automated synthesis of oligo- and polysaccharides.

专利号:US-2025019350-A1
优先权日:2023-06-16
标题 :Synthesis of the prostate specific membrane antigen (psma) radiolabeled inhibitor [18f]dcfpyl
发明人:BENITES PEDRO; ROBINSON SIMON P; SIEGLER ROBERT W
权利人:PROGENICS PHARM INC
摘要:Provided herein are methods and related compositions, including kits, for the improved synthesis, preparation and/or storage of [18F]DCFPyL. Also provided are methods of using [18F]DCFPyL, such as for imaging.

专利号:US-12122769-B2
优先权日:2017-10-19
标题 :Synthesis of antibacterial aminoglycoside analogs
发明人:TREND RAISSA; DAPPEN MICHAEL; HENRY CHRISTOPHER E; GOLDBLUM ADAM AARON; AGGEN JAMES BRADLEY; MENDONÇA RICARDO FILIPE DE JESUS GONÇALVES; SARDINHA JOÃO CARLOS FALCÃO
权利人:CIPLA USA INC
摘要:The present disclosure relates to novel methods for preparing antibacterial aminoglycoside compounds, as well as to related intermediates, and crystal forms thereof, useful in such methods.

专利号:US-2022387957-A1
优先权日:2019-11-04
标 题 :Microwave-assisted method for synthesis of oligo- and polysaccharides on solid phase

专利号:US-11453658-B2
优先权日:2017-10-19
标 题 :Synthesis of antibacterial aminoglycoside analogs

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Wever, R.; Babich, L.; Hartog, A. F., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 1, 226.
参考文献:10.1007/s00232-003-0626-y
摘要:Veyhl M, Wagner CA, Gorboulev V, Schmitt BM, Lang F, Koepsell H. Downregulation of the Na(+)- D-glucose cotransporter SGLT1 by protein RS1 (RSC1A1) is dependent on dynamin and protein kinase C. J Membr Biol. 2003 Nov 01;196(1):71–81. doi: 10.1007/s00232-003-0626-y.
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