CAS: 4891-38-7; Methyl Phenylpropiolate

上下游产品

methanol phenylpropyolic acid diazomethane phenyl(phenylethynyl)tellane4-phenyl-1H-pyrazole-3-carboxylic acid methyl ester methyl 3-phenyl-1H-pyrazole-4-carboxylate (2)H-pyrazole-3-carboxylic acid methyl ester4,5-diphenyl-1(2)H-pyrazole-3-carboxylic acid methyl ester hepta-2,5-diene-2-carboxylatemethyl 3-phenylbicyclo2.2.1hepta-2,5-diene-2-carboxylate

📜(碘乙炔基)苯置于3,4-Benzo-1,1,2,2-Tetraethyl-1,2-Disilacyclobutene,Cesium Fluoride体系中,用 乙醚,N,N-二甲基甲酰胺 作为反应溶剂,20.0 °C,101.33 Kpa 条件下,反应 2.17H,反应生成 苯丙炔酸甲酯
参考文献:A Strained Disilane-Promoted Carboxylation Of Organic Halides With Co2 Under Transition-Metal-Free Conditions
标题:A Strained Disilane-Promoted Carboxylation Of Organic Halides With Co2 Under Transition-Metal-Free Conditions
摘要:By Using A Strained Four-Membered Ring Disilane (3,4-Benzo-1,1,2,2-Tetraethyldisilacyclobutene) And Csf,A Wide Range Of Aryl,Alkenyl,Alkynyl,Benzyl,Allyl,And Alkyl Halides Was Successfully Carboxylated Under An Ambient Co2 Atmosphere (Co2 Balloon) At Room Temperature Within 2 H. In This Carboxylation,A Highly Reactive Silyl Anion,Which Is Generated From The Disilane And Csf,Is A Key To Facilitating The Formation Of A Carbanion Equivalent. The Resulting Anionic Species Can Be Trapped With Co2 To Produce Carboxylic Acids With High Efficiency.
DOI:10.1021/acs.Orglett.5B02645

专利信息

专利号:US-8153839-B2
优先权日:2005-09-14
标题:Method for synthesis of keto acids or amino acids by hydration of acetylene compound
发明人：OGO SEIJI; FUKUZUMI SHUN-ICHI
权利人:OGO SEIJI; FUKUZUMI SHUN-ICHI; JAPAN SCIENCE & TECH AGENCY
摘要:An object of the present invention is to provide a method for synthesis of keto acids by hydration of an acetylene compound (acetylene-carboxylic acids) under mild conditions free from harmful mercury catalysts and a method for synthesis of amino acids from acetylene-carboxylic acids in a single container (one-pot or tandem synthesis). In one embodiment of the method according to the present invention for synthesis of keto acids, acetylene-carboxylic acids is hydrated in the presence of a metal salt represented by General Formula (1), n nwhere M 1 represents an element in Group VIII, IX, or X of the periodic table, and X 1 , X 2 , or X 3 ligand represents halogen, H 2 O, or a solvent molecule, and k represents a valence of a cation species, and Y represents an anion species, and L represents a valence of the anion species, and each of K and L independently represents 1 or 2, and k×m=L×n.

专利号:EP-1932824-A1
优先权日:2005-09-14
标题:Method for synthesis of keto acid or amino acid by hydration of acethylene compound

专利号:US-2009216044-A1
优先权日:2005-09-14
标 题:Method for synthesis of keto acids or amino acids by hydration of acetylene compound

专利号:WO-2007032409-A1
优先权日:2005-09-14
标题 :Method for synthesis of keto acid or amino acid by hydration of acethylene compound

专利号:CN-103443101-A
优先权日:2011-03-10
标题 :Compound with fluorescent chromophore, ion concentration sensor containing compound, reagent containing compound, kit with reagent, precursor of compound, and synthesis method of compound

专利号:CN-118724798-A
优先权日:2024-07-18
标题 :Efficient synthesis method of (Z) -N-alkenyl-2-pyridone compound