CAS: 4295-36-7; 2,3-Dihydroquinolin-4(1H)-One

相似化合物

71412-22-1 179898-00-1 24206-39-1

上下游产品

1-乙酰基-2,3-二氢喹啉-4-酮 1-Acetyl-2,3-Dihydroquinolin-4(1H)-One 64142-63-8
4-氧代-1,2,3,4-四氢喹啉-3-羧酸甲酯 1,2,3,4-Tetrahydro-4-Oxochinolin-3-Carbonsaeure-Methylester 1136-75-0
4-氧代-3,4-二氢-2H-喹啉-1-羧酸叔丁酯 Tert-Butyl 4-Oxo-3,4-Dihydroquinoline-1(2H)-Carboxylate 179898-00-1

3-(2-Aminophenyl)Propyn-1-Ol置于tin(Ll) Chloride体系中,用 水,叔丁醇 作为反应溶剂,化学反应 1.0H,以66%的收率获得产物2,3-二氢-1H-喹啉-4-酮
参考文献:Synthetic Studies On Plakinidines
标题:Synthetic Studies On Plakinidines
摘要:
DOI:10.3987/com-18-S(F)26

专利信息

专利号:US-6664396-B1
优先权日:2002-06-27
标 题 :One step synthesis for quinacridone compounds
发明人：COSIMBESCU LELIA
权利人:EASTMAN KODAK CO
摘要:Disclosed is a process for forming a N,N'-diarylquinacridone compound comprising the step of reacting a N,N'-unsubstituted quinacridone compound with a haloaryl compound in the presence of a metal or metal compound to arylate the N and N' positions and form the corresponding N,N'-diarylquinacridone compound. The process is versatile and provides high yields and purity for the synthesis of N,N'-diarylquinacridone compounds.

专利号:US-7026481-B2
优先权日:2002-06-27
标题 :Synthesis for quinacridone compounds
发明人：COSIMBESCU LELIA; SHI JIANMIN
权利人:EASTMAN KODAK CO
摘要:Disclosed is a process for forming a N,N′-diarylquinacridone compound comprising the step of reacting a 1,4-dialkylcarboxylate-2,5-bis(N-arylamino) benzene with an iodoaryl compound to form the corresponding 2,5-bis(N-diarylamino) compound. The process is versatile and provides high yields and purity for the synthesis of N,N′-diarylquinacridone compounds.

专利号:US-4412075-A
优先权日:1981-01-16
标题 :Process for the preparation of quinolin-4-ones
发明人：BAUDOUIN MICHEL; DESBOIS MICHEL
权利人:RHONE POULENC SANTE
摘要:1,2,3,4-Tetrahydroquinolin-4-ones of the formula: ##STR1## wherein R represents a hydrogen or halogen atom, an alkyl radical (1 to 4 carbon atoms), an alkoxy radical (1 to 4 carbon atoms) or the trifluoromethyl radical, and R 1 represents a hydrogen atom, an alkyl radical (1 to 4 carbon atoms) or the trifluoromethyl radical, are prepared by cyclizing a 3-anilinopropionic acid of the formula: ##STR2## (wherein R and R 1 are as hereinbefore defined) in a mixture of hydrofluoric acid and boron trifluoride. n The quinolinone products are useful intermediates in the synthesis of therapeutically active substances.

专利号:WO-2015131100-A1
优先权日:2014-02-28
标题:Ligand-controlled c(sp3)-h arylation and olefination in synthesis of unnatural chiral alpha amino acids
发明人：YU JIN-QUAN
权利人:SCRIPPS RESEARCH INST
摘要:The use of ligands to tune the reactivity and selectivity of transition metal-catalysts for C(-sp3)-H bond functionalization is a central challenge in synthetic organic chemistry. Herein, we report a rare example of catalyst-controlled C(sp3)-H arylation using pyridine and quinoline derivatives: the former promotes exclusive monoarylation, whereas the latter activates the catalyst further to achieve diarylation. Successive application of these ligands enables the sequential diarylation of a methyl group in an alanine derivative with two different aryl iodides, affording a wide range of β-Ar-p-Ar ' -cc-amino acids with excellent levels of diastereoselectivity (d.r. > 20:1). Both configurations of the β-chiral center can be accessed by choosing the order in which the aryl groups are installed. The use of a quinoline derivative as a ligand also enables C(sp3)-H olefination of a protected alanine.

专利号:WO-2007072476-A2
优先权日:2005-12-23
标题 :Methods of preparing a crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-2(1h)-quinolinone and the use thereof in the synthesis of aripiprazole

专利号:CN-1513838-A
优先权日:2003-08-08
标题:One-pot synthesis of aripiprazole