该化合物是属于三苯乙烷染料类别的合成染料,其特点是充满活力的蓝色颜色,通常用作生物污点,特别是在生理学和微生物学中,因为它能够选择性地污损活细胞和某些细胞成分,染料具有分理性质,能够与核酸和磷酰胺等具有负电荷的细胞结构捆绑在一起.Janus Green B在水中溶解,具有不同的吸收频谱,因此对各种分析应用有用.除了污点外,还研究了其在光动疗法和红毒指标方面的潜在作用.然而,在处理Janus Green B时,应谨慎行事,因为它可能构成健康风险,包括潜在的毒性和环境关切.
专利号:US-11045458-B2 优先权日:2018-07-23 标 题:Synthesis of small molecule histone deacetylase 6 degraders, compounds formed thereby, and pharmaceutical compositions containing them 发明人:TANG WEIPING; Yang Ka; WU HAO 权利人:WISCONSIN ALUMNI RES FOUND 摘要:Histone deacetylase (“HDACâ€?)-selective inhibitors covalently bonded to a linker covalently bonded to an E3 ubiquitin ligase ligand, and salts thereof; pharmaceutical compositions containing them; methods of using the composition to inhibit neoplastic cell growth in mammals, including humans.
专利号:US-11059815-B2 优先权日:2018-07-23 标 题:Synthesis of small molecule histone deacetylase 6 degraders, compounds formed thereby, and pharmaceutical compositions containing them 发明人:TANG WEIPING; Yang Ka; WU HAO; ZHANG ZHONGRUI 权利人:WISCONSIN ALUMNI RES FOUND 摘要:Histone deacetylase (“HDACâ€?)-selective inhibitors covalently bonded to a linker covalently bonded to an E3 ubiquitin ligase ligand, and salts thereof; pharmaceutical compositions containing them; methods of using the composition to inhibit neoplastic cell growth in mammals, including humans.
专利号:US-10882842-B2 优先权日:2017-02-09 标 题:Pyridinium compounds, a synthesis method therefor, metal or metal alloy plating baths containing said pyridinium compounds and a method for use of said metal or metal alloy plating baths 发明人:JAGANNATHAN RANGARAJAN; ADOLF JAMES; WU JUN; KOHLMANN LARS; BRUNNER HEIKO 权利人:ATOTECH DEUTSCHLAND GMBH 摘要:The present invention concerns pyridinium compounds, a synthesis method for their preparation, metal or metal alloy plating baths containing said pyridinium compounds and a method for use of said metal or metal alloy plating baths. n The plating baths are particularly suitable for use in filling of recessed structures in the electronics and semiconductor industry including dual damascene applications.
专利号:US-2020190079-A1 优先权日:2018-07-23 标题 :Synthesis of small molecule histone deacetylase 6 degraders, compounds formed thereby, and pharmaceutical compositions containing them
专利号:US-2020022966-A1 优先权日:2018-07-23 标题 :Synthesis of small molecule histone deacetylase 6 degraders, compounds formed thereby, and pharmaceutical compositions containing them
专利号:US-2021322398-A1 优先权日:2018-07-23 标题:Synthesis of small molecule histone deacetylase 6 degraders, compounds formed thereby, and pharmaceutical compositions containing them
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合成参考文献
参考文献:10.1016/0165-0270(93)90105-z 摘要:Yack JE. Janus Green B as a rapid, vital stain for peripheral nerves and chordotonal organs in insects. J Neurosci Methods. 1993 Aug;49(1-2):17–22. doi: 10.1016/0165-0270(93)90105-z.