CAS: 20651-73-4; 4-Butylbenzonitrile

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CAS号623-03-0 对氯苯腈 | CAS号4426-47-5 正丁基硼酸 | CAS号15451-33-9 4-(4-CYANOPHENY... | CAS号109-72-8 正丁基锂 | CAS号6638-68-2 1,3,2-Dioxaboro... | CAS号138373-10-1 (4-cyanophenyl)... | CAS号693-04-9 正丁基氯化镁 | CAS号623-26-7 对苯二甲腈 | CAS号109-65-9 正溴丁烷 | CAS号57802-79-6 4-正丁基苄胺 | CAS号38454-28-3 4-正丁基苯甲酸 4-己氧基苯酯 | CAS号29147-98-6 4-正丁基苯甲脒盐酸盐 | CAS号35684-23-2 p-Butylbenzoic ... | CAS号20651-71-2 4-丁基苯甲酸

📜4-丁基苯酚置于吡啶,Aluminum (III) Chloride,Bis(1,5-Cyclooctadiene)Nickel (0),三乙胺,4,5-双二苯基膦-9,9-二甲基氧杂蒽体系中,用 二氯甲烷,甲苯 用作溶剂,化学反应 2.0H,反应生成4-N-丁基苯甲腈
参考文献:丁腈对镍催化的芳基氯化物和三氟甲磺酸酯的氰化反应:将逆向氢氰化与交叉偶联合并
标题:丁腈对镍催化的芳基氯化物和三氟甲磺酸酯的氰化反应:将逆向氢氰化与交叉偶联合并
摘要:我们描述了芳基(假)卤化物的镍催化氰化反应,该反应采用丁腈作为氰化试剂代替剧毒的氰化物盐.将逆向氢氰化和交叉偶联相结合的双催化循环可将多种芳基氯和芳基/乙烯基三氟甲磺酸转化为相应的腈.该新反应为安全制备芳基氰化物提供了战略上独特的方法,芳基氰化物是农业化学和药物化学中必不可少的化合物.
Doi:10.1002/anie.201707517

专利信息

专利号:US-4536599-A
优先权日:1978-08-22
标题:Synthesis of amine derivatives
发明人：MASUKO FUJIO; KATSURA TADASHI
权利人:SUMITOMO CHEMICAL CO
摘要:An amine of the formula, ##STR1## wherein R 1 , R 2 , R 3 , R 4 and R 5 are each hydrogen, alkyl or the like and n is 1, 2 or 3, including α-phenyl-β-(p-tolyl)-ethylamine, which is useful as an optically resolving agent, an intermediate of medicines and the like, is effectively produced by a novel process comprising hydrolysis of the corresponding nitrile of the formula, ##STR2## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above, followed by alkali-decomposition of the resulting amide of the formula, ##STR3## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above. An amide including the above one is effectively produced by hydrolysis of the corresponding nitrile in the presence of a base and hydrogen peroxide using an organic quaternary ammonium salt and/or a tertiary amine as a catalyst.

专利号:EP-0008532-A1
优先权日:1978-08-22
标 题 :Synthesis of amines

专利号:EP-0008532-B1
优先权日:1978-08-22
标 题 :Synthesis of amines

专利号:EP-0040896-A2
优先权日:1978-08-22
标 题 :Synthesis of amides

专利号:CN-103857667-A
优先权日:2011-10-22
标 题 :Composition, Synthesis and Application of a Group of Hydantoin Derivatives