CAS: 115-67-3; 5-Ethyl-3,5-Dimethyloxazolidine-2,4-Dione

该化合物是一种化学化合物,其特点是氧化氮和氧原子,其结构为五人环,含有氮和氧原子,这种化合物一般显示白色和非白晶状晶状,可溶于有机溶剂,因其在医药化学中的潜在应用,特别是作为合成各种药物的一个构件,而已知该化合物在各种药物中的潜在应用,乙基和二甲基替代成分的存在有助于其独特的化学特性,影响其再活性和与生物系统的互动.此外,这一类化合物可能展示出有趣的生物活动,包括抗微生物或抗硫酸盐特性,使其对药物开发具有兴趣.应当参考安全数据,以便处理和接触准则,如任何化学物质一样,确保适当的实验室做法.

结构式图片

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号77-78-1 硫酸二甲酯 | CAS号74-88-4 碘甲烷

合成工艺路线路线简述

    📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于四氯化碳,水,氯体系中,化学反应生成甲乙双酮
    参考文献:Davies Et Al.,Journal Of The Chemical Society,1950,P. 34
    标题:Davies Et Al.,Journal Of The Chemical Society,1950,P. 34

    海关参考信息

    专利信息


    专利号:US-2008214827-A1
    优先权日:2004-02-03
    标 题:Synthesis of Cyanoimino-Benzoimidazoles
    发明人：GOEHRING R RICHARD; WHITEHEAD JOHN; SHAO BIN
    权利人:EURO CELTIQUE SA
    摘要:Disclosed in certain embodiments is a process for synthesizing a compound of formula (V) and salts thereof.

    专利号:US-6030613-A
    优先权日:1995-01-17
    标题:Receptor specific transepithelial transport of therapeutics
    发明人：BLUMBERG RICHARD S; SIMISTER NEIL E; LENCER WAYNE I
    权利人:BRIGHAM & WOMENS HOSPITAL; UNIV BRANDEIS
    摘要:The present invention relates in general to methods and products for initiating an immune response against an antigen, and in particular relates to transepithelial delivery of antigens to provoke tolerance and immunity. The present invention further relates to methods and products for the transepithelial delivery of therapeutics. In particular, the invention relates to methods and compositions for the delivery of therapeutics conjugated to a FcRn binding partner to intestinal epithelium, mucosal epithelium and epithelium of the lung. The present invention further relates to the synthesis, preparation and use of the FcRn binding partner conjugates as, or in, pharmaceutical compositions for oral systemic delivery of drugs and vaccines.

    专利号:CA-2555219-A1
    优先权日:2004-02-03
    标 题 :Synthesis of cyanoimino-benzoimidazoles

    专利号:US-7547436-B2
    优先权日:1995-01-17
    标 题:Receptor specific transepithelial transport of therapeutics
    发明人：BLUMBERG RICHARD S; LENCER WAYNE I; SIMISTER NEIL E
    权利人:BRIGHAM & WOMENS HOSPITAL; UNIV BRANDEIS
    摘要:The present invention relates in general to methods and products for initiating an immune response against an antigen, and in particular relates to transepithelial delivery of antigens to provoke tolerance and immunity. The present invention further relates to methods and products for the transepithelial delivery of therapeutics. In particular, the invention relates to methods and compositions for the delivery of therapeutics conjugated to a FcRn binding partner to intestinal epithelium, mucosal epithelium and epithelium of the lung. The present invention further relates to the synthesis, preparation and use of the FcRn binding partner conjugates as, or in, pharmaceutical compositions for oral systemic delivery of drugs and vaccines.

    专利号:US-8945508-B2
    优先权日:2009-10-13
    标 题 :Dendrimer compositions and methods of synthesis
    发明人：BAKER JR JAMES R; HUANG BAOHUA
    权利人:BAKER JR JAMES R; HUANG BAOHUA; UNIV MICHIGAN
    摘要:The present invention relates to novel dendrimer compounds and methods of synthesizing the same. In particular, the present invention is directed to novel polyamidoamine (PAMAM) dendrimers, novel dendrimer branching units, methods for synthesizing such novel PAMAM dendrimers and functionalized dendrimers, as well as systems and methods utilizing the dendrimers (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease diagnosis and/or therapy, etc.))).

    专利号:WO-2005075459-A1
    优先权日:2004-02-03
    标题:Synthesis of cyanoimino-benzoimidazoles

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    主要参考文献


    1: Best K. Epilepsy drugs may reduce method effectiveness. Netw Res Triangle Park N C. 1999 Winter;19(2):12. 168(6 Pt 2):2027-32. doi: 10.1016/s0002-9378(12)90945-x. 99(4):253-61. doi: 10.1007/BF00204436.
    94:39-43. 4(5):481-90. Italian. 4(8):576-83. doi: 10.1248/bpb1978.4.576. 76(6):827. 37(10):1333-8. 131(12):1389-92. doi: 10.1001/archpedi.1977.02120250071012. 60(3):635-41. 77(8):11. Danish. 64(10):1702-3. doi: 10.1002/jps.2600641027. 2(7666):261-2. doi: 10.1016/s0140-6736(70)92608-5. 202(9):893-4.
    30:601-7. 79(6):243-5. 253(4):138-43. doi: 10.1056/NEJM195507282530405. dimedione as compared with tridione, paradione and milontin in clinical use]. Ugeskr Laeger. 1955 Mar 24;117(12):350-4. Danish. 113(2):238-40. 113(2):178-85.

    合成参考文献


    摘要:HOFFMAN DJ, CHUN AHC; J PHARM SCI 64(OCT) 1702-3 (1975)
    摘要:Weast, R.C. (ed.). Handbook of Chemistry and Physics. 60th ed. Boca Raton, Florida: CRC Press Inc., 1979., p. C-501
    摘要:Hardman, J.G., L.E. Limbird, P.B. Molinoff, R.W. Ruddon, A.G. Goodman (eds.). Goodman and Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York, NY: McGraw-Hill, 1996., p. 478
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