CAS: 1121-58-0; 4-(Methylamino)Pyridine

相似化合物

98400-69-2 1122-58-3 1122-58-3

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CAS号19524-06-2 4-溴吡啶盐酸盐 | CAS号74-89-5 氨基甲烷 | CAS号7379-35-3 4-氯吡啶盐酸盐 | CAS号1120-87-2 4-溴吡啶 | CAS号504-24-5 4-氨基吡啶 | CAS号541-41-3 氯甲酸乙酯 | CAS号626-61-9 4-氯吡啶 | CAS号2196-95-4 2,2'-diphenyl-Δ... | CAS号50-00-0 甲醛 | CAS号5421-92-1 4-吡啶基吡啶氯盐酸盐 | CAS号16219-99-1 4-nitrosomethyl... | CAS号1633-41-6 4-甲氨基-3-硝基吡啶 | CAS号1158958-94-1 双[甲基-(4-吡啶基)硫代氨... | CAS号80028-41-7 Hexanoic acid,6...

4-(Methylamino)Pyridine-2,6-Dicarboxylic Acid 反应生成4-甲氨基吡啶
参考文献:Koenigs; Friedrich; Jurany,Chemische Berichte,1925,Vol. 58,P. 2574
标题:Koenigs; Friedrich; Jurany,Chemische Berichte,1925,Vol. 58,P. 2574

专利信息

专利号:US-5554725-A
优先权日:1994-09-14
标题:Synthesis of dolastatin 15
发明人：PETTIT GEORGE R
权利人:UNIV ARIZONA
摘要:The present invention relates to the synthesis of natural (-)- dolastatin and the elucidation of the absolute configuration of this important sea hare constituent. A segment synthetic strategy was utilized for obtaining the Dolabella auricularia (Indian Ocean sea hare) depsipeptide dolastatin 15. Reaction of protected (S)-Hiva-(S)-Phe (2c) with isopropenyl chloroformate followed by Meldrum's ester, cyclization (2c→3a) of the product in toluene and finally methylation afforded the key (S)-dolapyrrolidine (Dpy) derivative (3b). Condensation of tripeptide (8) with the three unit Dpy segment (5b) followed by deprotection and coupling (diethyl phosphorocyanidate) led to dolastatin 15 in 11% overall yield. The powerful and selective activity of dolastatin 15 against the U.S. National Cancer Institute's panel of human cell lines is reported.

专利号:US-7157477-B2
优先权日:2000-10-25
标题 :Aliphatic amino-substituted demethoxylated hypocrellins and their synthesis
发明人：ZHANG MANHUA; XU SHANGJIE; WU TAO; CHEN SHEN; SHEN TAO
权利人:INST OF PHOTOGRAPHIC CHEMISTRY
摘要:The invention involves a methods and compositions for use in photodynamic therapy. Novel perylenequinone derivatives, conjugates comprising perylenequinone derivatives and a binding agent, and methods of treatment using these compositions are disclosed. The present invention relates to the field of photosensitizers possessing photodynamic activities. They possess high photodynamic activities and low dark toxicities, which makes them as more potent photodynamic agents than HPD against cancer and AIDS virus.

专利号:US-5128489-A
优先权日:1989-10-05
标题:Process for production of optically active 2-(tetrahydropyran-2-yloxy)-1-propanol
发明人：KUMOBAYASHI HIDENORI; TACHIKAWA AKIO; OKEDA YOSHIKI; FUJIWARA TOSHIHIRO
权利人:TAKASAGO PERFUMERY CO LTD; DAIICHI SEIYAKU CO
摘要:A process for production of an optically active isomer of 2-(tetrahydropyran-2-yloxy)-1-propanol represented by formula (I): ##STR1## is disclosed, which comprises reacting an optically active isomer of a 1-acyloxy-2-propanol represented by formula (II): ##STR2## wherein R is a substituted or unsubstituted aryl group, with 3,4-dihydro-2H-pyran to obtain an optically active isomer of a 1-acyloxy-2-(tetrahydropyran-2-yloxy)propane represented by formula (III): ##STR3## wherein R is as defined above, and hydrolyzing the compound (III) to eliminate the acyl group. The optically active isomer of 2-(tetrahydropyran-2-yloxy)-1-propanol represented by formula (I) is an intermediate for synthesis of pyridobenzoxazine derivatives useful as a synthetic antibacterial agent, particularly an optically active isomer of ofloxacin.

专利号:US-9006347-B2
优先权日:2011-09-08
标 题 :Method of synthesising polycarbonates in the presence of a bimetallic catalyst and a chain transfer agent
发明人：WILLIAMS CHARLOTTE K; KEMBER MICHAEL; BUCHARD ANTOINE; JUTZ FABIAN
权利人:IMP INNOVATIONS LTD
摘要:The invention provides a process for the synthesis of a polycarbonate, the process comprising the step of reacting carbon dioxide with at least one epoxide in the presence of a catalyst of formula (I) and a chain transfer agent. The invention also provides a polymerization system for the copolymerization of carbon dioxide and at least one epoxide comprising a catalyst of formula (I) and a chain transfer agent, polycarbonates produced by the inventive process, a block copolymer comprising a polycarbonate produced by the inventive process, and a method of producing the block copolymer. The invention also relates to novel catalysts of formula (III).

专利号:US-6069243-A
优先权日:1998-10-06
标 题 :Process for oligonucleotide synthesis
发明人：SCOZZARI ANTHONY
权利人:ISIS PHARMACEUTICALS INC
摘要:The present invention describes methods for linking phosphoramidite nucleosides to a solid support-bound nucleoside. This invention presents novel processes for synthesizing oligonucleotides. Acetonitrile having a water content between 30 ppm and about 1250 ppm is used as the solvent for the washing steps in solid phase oligonucleotide synthesis, or is used as a solvent for the capping reagent or oxidizing reagent. The processes of the present invention are amenable to large-scale, economic oligonucleotide synthesis using the phosphoramidite method.

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人：BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.