CAS: 10255-95-5; 2-Phenylmalonamide

该化合物其结构特征为:以苯基组物替代了马龙胺骨干;该化合物一般是白色的,以在有机合成和药用化学中的潜在用途而著称;它拥有能够参与各种化学反应的功能组,使其成为合成更复杂的分子的多功能中间体;氨基功能组的存在有助于其形成氢联结的能力,影响其溶解性和再活性;此外,二-苯甲胺可能展示生物活动,可以用于药物应用,其熔点,沸点和溶性特性可以因纯度和环境条件而变化;应查阅安全数据,以适当处理化合物,因为如果浸入或吸入,可能会对健康造成危害;

结构式图片

相似化合物

3041-40-5 771-84-6 5841-70-3

上下游产品

pyridine benzaldehyde formamide dimethyl 2-phenylmalonate 5-phenyl-2,4,6-pyrimidinetrione 4-phenyl-pyrrolidine-2,3,5-trione 8-methyl-3-phenyl-quinoline-2,4-diol H-pyrimidine-4,6-dione5-phenyl-1H-pyrimidine-4,6-dione

合成工艺路线路线简述

  • 合成目标产物 2-Phenylmalonamide 主要起始原料 Dimethylphenylmalonate
  • (文献来源)合成步骤主要原料 Dimethylphenylmalonate
📜Dimethyl 2-Phenylmalonate置于ammonium Hydroxide体系中,化学反应生成2-苯基丙二酰胺
参考文献:Budesinsky,Z. Et Al.,Collection Of Czechoslovak Chemical Communications,1965,Vol. 30,P. 3730-3743
标题:Budesinsky,Z. Et Al.,Collection Of Czechoslovak Chemical Communications,1965,Vol. 30,P. 3730-3743

专利信息


专利号:US-11180508-B2
优先权日:2017-12-05
标 题:Chemical process for the synthesis of herbicidal pyrazolidinedione compounds
发明人:MORRIS JAMES ALAN; SHAFIR ALEXANDR; GONU MALLIKHARJUNA; BILAL IFFAT; SALE DAVID ALEXANDER
权利人:SYNGENTA PARTICIPATIONS AG
摘要:The present invention relates to a novel process for the synthesis of herbicidal pyrazolidinedione compounds. In particular, a process for the preparation of a compound of formula (I), wherein R1, R2 and R3 are as defined herein. The present invention further relates to novel intermediate compounds utilized in said process, and methods for preparing said intermediate compounds.

专利号:EP-3720861-A1
优先权日:2017-12-05
标 题:Chemical process for the synthesis of herbicidal pyrazolidinedione compounds

专利号:WO-2019110613-A1
优先权日:2017-12-05
标 题 :Chemical process for the synthesis of herbicidal pyrazolidinedione compounds

专利号:CA-3084563-A1
优先权日:2017-12-05
标 题:Chemical process for the synthesis of herbicidal pyrazolidinedione compounds

专利号:US-2021171540-A1
优先权日:2017-12-05
标题:Chemical process for the synthesis of herbicidal pyrazolidinedione compounds

专利号:EP-3720861-B1
优先权日:2017-12-05
标题 :Chemical process for the synthesis of herbicidal pyrazolidinedione compounds

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 147.
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