CAS: 77168-37-7; 2-(2-(Methylthio)Pyrimidin-4-yl)Malonaldehyde

该化合物是一种化学化合物,其特征为:其火利因环状结构,由甲基硫基组和杂质杂交替代.该化合物通常具有与七环化合物有关的特性,包括因其在各种生物化学过程中的作用而闻名的青糖环的存在而可能具有的生物活动.甲基基奥组可能影响化合物的溶性和再活动,而丙基苯组则表明存在甲酰胺功能,可以参与各种化学反应,例如凝聚和核分裂性添加.该化合物的分子结构可能会赋予特定的药用化学特性,包括因其在各种生物化学过程中的作用而闻名的亚麻利胺环的存在.此外,其稳定性,溶解性和再活性可能因环境条件和其他化学物种的存在而有所变化.

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    上下游产品

    CAS号14001-63-9 4-甲基-2-甲硫基嘧啶 | CAS号68-12-2 N,N-二甲基甲酰胺

    合成工艺路线路线简述

      📜4-甲基-2-甲硫基嘧啶,N,N-二甲基甲酰胺置于光气体系中,化学反应生成 2-(2-甲硫基嘧啶-4-基)丙二醛
      参考文献:Brown,Desmond J.; Cowden,William B.; Grigg,Geoffrey W.,Australian Journal Of Chemistry,1980,Vol. 33,# 10,P. 2291-2298
      标题:Brown,Desmond J.; Cowden,William B.; Grigg,Geoffrey W.,Australian Journal Of Chemistry,1980,Vol. 33,# 10,P. 2291-2298

      海关参考信息

      专利信息


      专利号:US-11225655-B2
      优先权日:2010-04-16
      标题:Bi-functional complexes and methods for making and using such complexes
      发明人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
      权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
      摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

      专利号:US-7772246-B2
      优先权日:2007-08-01
      标题:Pyrazole compounds as RAF inhibitors
      发明人:CUI JINGRONG JEAN; DEAL JUDITH GAIL; GU DANLIN; GUO CHUANGXING; JOHNSON MARY CATHERINE; KANIA ROBERT STEVEN; KEPHART SUSAN ELIZABETH; LINTON MARIA ANGELICA; MCALPINE INDRAWAN JAMES; PAIRISH MASON ALAN; PALMER CYNTHIA LOUISE
      权利人:PFIZER
      摘要:The present invention is directed to compounds of Formula (I), n nand to pharmaceutically acceptable salts thereof, their synthesis, and their use as Raf inhibitors.

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