CAS: 6004-60-0; 1-Cyclopentylethanone

相似化合物

52829-98-8 4971-18-0 167303-65-3

上下游产品

2-甲基环己酮 2-Methylcyclohexanone 583-60-8
2-乙酰基环戊酮 2-Acetylcyclopentanaone 1670-46-8
3-乙酰基环戊酮 3-Acetylcyclopentanone 84602-27-7
环己烷基甲醛 Cyclohexanecarbaldehyde 2043-61-0
1-(1-羟基环戊基)-乙酮 1-Acetylcyclopentanol 17160-89-3

1-Methyl-1,2-Cyclohexanediol置于氧气,氘体系中,用45.3%的收率获得产物环戊基乙酮
参考文献:顺式和反式-1-甲基环己烷-1,2-二醇的气相频哪醇重排中的立体化学效应
标题:顺式和反式-1-甲基环己烷-1,2-二醇的气相频哪醇重排中的立体化学效应
摘要:顺式和反式-1-甲基-1,2-环己二醇的气相频哪醇重排.通过辐射分解方法研究了在100-760 Torr的压力下由d 3 +和c N H 5 +(n = 1,2)促进的碳原子.在所有条件下,2-甲基-环己酮是主要产物,由两种底物通过不同的频哪醇重排和相应的主要中间体(例如0质子化的1-甲基-1-环戊烷甲醛)的连续快速异构化而产生.该结论基于以频哪醇为参考底物的竞争实验的动力学分析,该实验是在有或没有添加碱(nme 3)的高压(760 Torr)下进行的,3 Torr).表明频哪醇重排速率明显取决于二醇的立体化学特征.因此,反式二醇比顺式异构体重排更快,后者反式异构化比频哪醇更快,表明反平面ch 2迁移到反式(k2)的邻级叔c-Oh 2 +中心比h快五倍以上.顺式(k3)迁移.分析不同ch 2部分在反式(k2> K1)中的相对迁移能力,可以排除在这些气相频哪醇重排中可观的邻氨基苯甲酸酯助剂.
DOI:10.1016/s0040-4020(01)86188-3

专利信息

专利号:US-5225591-A
优先权日:1992-07-28
标题 :Process for making 1-cyclopentylalyl amines useful for the synthesis of sweeteners
发明人：SWEENY JAMES G; D ANGELO LIHONG L
权利人:COCA COLA CO
摘要:The disclosed process relates to a method for preparing 1-cyclopentylalkyl amines, useful in the synthesis of artificial sweeteners, by reducing an azanorbornene in a high-yield one-step reduction of an azanorbornene, wherein the method involves use of a solvent reductant system with catalyst that is compatible with the production of edible food compositions.

专利号:US-7951905-B2
优先权日:2006-09-18
标 题 :Synthesis of carbohydrate-templated amino acids and methods of using same
发明人：SCHWEIZER FRANK; ZHANG KAIDONG; OWENS NEIL; ZHANEL GEORGE
权利人:UNIV MANITOBA
摘要:The present invention generally relates to tetrahydropyranyl-derivatized amino acids, their syntheses and their incorporation into peptides and peptidomimetics. The tetrahydropyran moiety constrains the side chain of an amino acid, thereby providing a molecule that may act as a sugar- or amino acid-mimetic as well as a scaffold for combinatorial synthesis.

专利号:US-9724682-B2
优先权日:2013-02-26
标 题 :Synthesis of acyclic and cyclic amines using iron-catalyzed nitrene group transfer
发明人：BETLEY THEODORE ALEXANDER; HENNESSY ELISABETH THERESE
权利人:HARVARD COLLEGE
摘要:The present invention provides novel synthetic methods for making acyclic secondary amines by reacting an azide with a compound bearing one or more C—H groups, catalyzed by a Fe II -dipyrromethene complex. The acyclic secondary amines are thought to be formed through an intermolecular nitrene transfer. Also provided herein are methods of synthesizing protected (e.g., Boc- or Fmoc-protected) cyclic secondary amines (e.g., 5-, 6-, and 7-membered cyclic secondary amines) by reacting an azide that bears one or more C—H groups, catalyzed by a Fe II -dipyrromethene complex. The protected cyclic secondary amines are thought to be formed through an intramolecular nitrene transfer and may be subsequently deprotected to yield cyclic secondary amines.

专利号:US-6005103-A
优先权日:1993-11-19
标题 :Pyrone derivatives as protease inhibitors and antiviral agents
发明人：DOMAGALA JOHN MICHAEL; LUNNEY ELIZABETH; PARA KIMBERLY SUZANNE; PRASAD JOSYULA VENKATA NAGENDR; TAIT BRADLEY DEAN
权利人:WARNER LAMBERT CO
摘要:The present invention relates to novel tri- and tetrasubstituted pyrones and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The pyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized pyrones and of related structures.

专利号:DE-1593081-A1
优先权日:1965-09-09
标题:Process for the preparation of intermediates for the synthesis of steroids of the oestrane series and compounds of this kind

专利号:US-2011124634-A1
优先权日:2008-05-13
标 题:Bioactive compounds for treatment of cancer and neurodegenerative diseases
发明人：SUN CONNIE L; LI XIAOYUAN
权利人:PONIARD PHARMACEUTICALS INC
摘要:The invention provides bioactive compounds for the treatment of various malconditions such as cancer and neurodegenerative diseases including Alzheimer's disease. The chemical compounds as disclosed herein are found to show bioactivity in bioassays related to these conditions. Pharmaceutical compositions, combinations and methods of synthesis are provided, as are methods of using the compound, compositions and combinations in the treatment of the diseases.