专利号:US-12139504-B2 优先权日:2022-08-09 标 题:Vanadium alkylidene complex, synthesis and use thereof 发明人:BUKHRYAKOV KONSTANTIN; BELOV DMITRY 权利人:BUKHRYAKOV KONSTANTIN; BELOV DMITRY; THE FLORIDA INTERNATIONAL UNIV BOARD OF TRUSTEES 摘要:The subject invention provides catalytical compounds/complexes, compositions comprising such compound/complex, synthesis of the compounds/complexes, and methods of using such compounds/complexes as catalysts in, for example, RCM reactions. Specifically, the subject invention provides the synthesis of the first catalytically active V oxo alkylidene, VO(CHSiMe 3 )(PEt 3 ) 2 Cl, which exhibits superior performance compared to other analogs.
专利号:US-9255117-B2 优先权日:2006-07-13 标题 :Synthesis of terminal alkenes from internal alkenes and ethylene via olefin metathesis 发明人:SCHRODI YANN 权利人:MATERIA INC 摘要:This invention relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by a selected olefin metathesis catalyst. In one embodiment of the invention, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting an olefinic substrate comprised of at least one internal olefin with ethylene, in the presence of a metathesis catalyst, wherein the catalyst is present in an amount that is less than about 1000 ppm relative to the olefinic substrate, and wherein the metathesis catalyst has the structure of formula (II) n nwherein the various substituents are as defined herein. The invention has utility, for example, in the fields of catalysis, organic synthesis, and industrial chemistry.
专利号:US-2023183177-A1 优先权日:2020-04-24 标题:Enantioselective chemo-enzymatic synthesis of optically active amino amide compounds 发明人:GRILL BIRGIT; WINKLER MARGIT; SCHWAB HELMUT; STROHMEIER GERNOT; DONSBACH KAI; WALDVOGEL SIEGFRIED R; ARNDT SEBASTIAN; WEIS DOMINIK 权利人:PHARMAZELL GMBH 摘要:The present invention relates to a novel biocatalytic process for the stereoselective preparation of alpha amino amide compounds catalyzed by NHase enzymes. A further aspect of the invention relates to novel NHase enzymes as well as further improved NHase enzyme mutants, nucleic acid molecules encoding these enzymes, recombinant microorganisms suitable for preparing such enzymes and mutants. Another aspect of the invention relates to a chemo-biocatalytic process for the preparation of lactam compounds comprising the new catalytic process for the preparation of alpha amino amide compounds catalyzed by NHase enzymes, as well as the chemical oxidation of the alpha amino amide by applying certain chemical oxidation catalysts suitable for converting the alpha amino amide under retention of its stereochemical configuration to the respective lactam. The novel chemo-biocatalytic process is particularly suited for the synthesis of valuable pharmaceutical compounds, like in particular (S)-Levetiracetam.
专利号:US-2019228842-A1 优先权日:2017-11-17 标 题 :Recipe for the synthesis of metastable structures using topologically assembled precursors 发明人:JENA PURUSOTTAM; FANG HONG 权利人:UNIV VIRGINIA COMMONWEALTH 摘要:Methods of planning and executing the synthesis of metastable materials are provided. Topologically assembled precursors having potential energy surfaces in which the volumes of potential wells of certain local minima are increased are created in silico. The precursor molecules are used to synthesize, e.g. two-dimensional metastable carbon materials such as penta-graphene comprised entirely of pentagons, O-graphene comprised of five- and eight-membered rings, and R-graphene comprised of four-, six- and eight-membered rings.
专利号:US-9382189-B2 优先权日:2013-02-08 标题:Synthesis of a branched unsaturated compound by means of cross metathesis 发明人:DUBOIS JEAN-LUC; COUTURIER JEAN-LUC 权利人:ARKEMA FRANCE 摘要:The invention relates to a method for the synthesis of a branched unsaturated fatty compound, said method comprising the metathesis, in the presence of a metathesis catalyst, of a linear unsaturated fatty compound and a branched olefin. The branched unsaturated fatty compound is used in particular for the production of at least one of the following products: dielectric fluids, specialty surfactants, emulsifiers, frictions agents, antistatic additives, antifogging additives, mould release agents, pigment dispersants, high-performance lubricants, waxes and wax emulsifiers, polymer conversion additives, PVC stabilizing agents, inks, resins, paints, varnishes, solvents, lipsticks, creams for the skin, deodorants, particularly stick deodorants, hair dyes, shampoos and other liquid soaps, shaving foam, laundry detergents, cleaning agents, fabric softeners, and mixtures of same.
专利号:US-11306041-B2 优先权日:2017-03-30 标 题:Catalytic synthesis of super linear alkenyl arenes using rhodium catalysts 发明人:SCHINSKI WILLIAM; GOLDMAN ALAN; GUNNOE THOMAS B; WEBSTER-GARDINER MICHAEL S; SCHWARTZ NICHOLE 权利人:UNIV VIRGINIA PATENT FOUNDATION 摘要:Catalytic methods for synthesis of super linear alkenyl arenes and alkyl arenes are provided. The methods are capable of synthesizing super linear alkyl and alkenyl arenes from simple arene and olefin starting materials and with high selectivity for linear coupling. Methods are also provided for making a 2,6-dimethylnapthalene (DMN) or 2,6-methylethylnapthalene (MEN).