CAS: 5339-85-5; 2-(2-Aminophenyl)Ethanol

上下游产品

2-nitro-benzeneethanol 2-(2-nitrophenyl)ethyl nitrate formaldehyd 1-methyl-2-nitrobenzene N-[2-(2-hydroxy-ethyl)-anilinomethyl]-phthalimideN-[2-(2-hydroxy-ethyl)-anilinomethyl]-phthalimide 2-methylsulfanyl-phenethyl alcohol 1-indoline 2.3-dihydrobenzofuran

甲基硝基苯置于氢气,Potassium Hydroxide体系中,用 甲醇,水,二甲基亚砜 作为反应溶剂,20.0 °C,300.01 Kpa 条件下,反应 4.0H,反应生成 2-氨基苯乙醇
参考文献:镍催化氨基醇及醇类直接合成n-取代吲哚
标题:镍催化氨基醇及醇类直接合成n-取代吲哚
摘要:报道了在无添加剂和无碱条件下从氨基醇和醇合成n-取代吲哚的单锅级联方法,释放的水是唯一的化学计量副产物.市售的稳定型 Ni(Otf) 2盐与 1,2-双(二环己基膦基)乙烷 (Dcype) 相结合,对于这种前所未有的催化转化非常有效.在反应条件下使用范围广泛的底物,包括芳香族和脂肪族伯醇,环状和非环状仲醇以及各种取代的 2-氨基苯基乙醇,以提供各种n-烷基化吲哚.机理研究表明,反应通过串联n-通过氢自动转移进行烷基化,然后是n-烷基化醇中间体的环化.
DOI:10.1021/acs.Orglett.2C03617

专利信息

专利号:US-2023348492-A1
优先权日:2020-05-04
标题:Photochemical synthesis of marmycin analogues through a new photochemical reaction involving carbonyl compounds
发明人：SIVAGURU JAYARAMAN; KANDAPPA SUNIL KUMAR; VALLOLI LAKSHMY KANNADI
权利人:BOWLING GREEN STATE UNIV
摘要:Photochemical reactivity of carbonyl compounds leading to the synthesis of the Marmycin core is described. The photochemical reactivity involves an excited state reaction that provides convenient access to bicyclic compounds. The disclosed reactivity is a new photochemical pathway involving 1,3-dicarbonyl compounds and amines as well as for enaminones.

专利号:US-6235871-B1
优先权日:1997-12-03
标题:Synthesis of oligoarylamines, and uses and reagents related thereto
发明人：SINGER ROBERT A; SADIGHI JOSEPH P; BUCHWALD STEPHEN L; MACKEWITZ THOMAS
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The transition metal-catalyzed amination of aryl halides, in conjunction with an orthogonal protective group scheme, forms the basis of two routes to oligoaniline precursors. The oligoaniline precursors are soluble in a variety of common organic solvents, and are easily converted to the deprotected oligoanilines. The method allows the preparation of oligoanilines of even or odd chain lengths, and the incorporation of a variety of functional groups into the oligomers. Polyanilines of low polydispersity can also be prepared by this method.

专利号:US-4886887-A
优先权日:1985-11-08
标 题 :Process for the preparation of indolines
发明人：AEBLI BEAT M; GREMMELMAIER CLAUDE
权利人:CIBA GEIGY CORP
摘要:Indolines of the formula ##STR1## wherein R 1 is hydrogen or C 1 -C 4 alkyl and each of R 2 and R 3 independently of the other is hydrogen, C 1 -C 4 alkyl or phenyl, are prepared by cyclodehydrating a 2-(2'-aminophenyl)ethanol of formula ##STR2## wherein R 1 , R 2 and R 3 are as defined above, at 150°-350° C. in the presence of an amorphous aluminum silicate. n The indolines of the above formula are useful intermediates for the synthesis of plant protective agents.

专利号:US-10125226-B2
优先权日:2013-06-05
标 题 :Scale-up process of bifunctionalized triblock copolymers with secondary and tertiary amines, with application in dewatering and desalting of heavy crude oils
发明人：FLORES SANDOVAL CESAR ANDRES; FLORES OROPEZA EUGENIO ALEJANDRO; LOPEZ ORTEGA ALFONSO; HERNANDEZ CORTEZ JOSE GONZALO; ESTRADA BUENDIA ARISTEO; CASTRO SOTELO LAURA VERONICA; REYES MARTINEZ REYNA; ALVAREZ RAMIREZ FERNANDO; ESTRADA MARTINEZ ARQUIMEDES; VAZQUEZ MORENO FLAVIO SALVADOR
权利人:MEXICANO INST PETROL
摘要:A chemical synthesis process is provided for the functionalization of monodispersed triblock copolymer (POEw-POPy-POEw) with secondary or tertiary amines at a semi-industrial level in glass reactors having a capacity between 1 L and 100 L. The process includes two stages where the first stage uses an alkylsulfonyl or arylsulfonyl chloride to obtain better leaving groups, and the second stage is the nucleophilic substitution with secondary or tertiary amines, to obtain the bifunctionalized triblock copolymers. The main advantage for this process is to reduce the quantity of unitary process done in each stage, the optimization of reaction times, and the stoichiometric relationships.

专利号:EP-0844261-A1
优先权日:1996-11-21
标题:Dispersions containing polyurethanes with carbonyl groups in ketone function
发明人：KOKEL NICOLAS DR; GULBINS ERICH DR; RAU MARIA GYOPAR DR; FISCHER GERHARD
权利人:BASF AG
摘要:R 1 , R 2 , R 3 jeweils Wasserstoff, C 1 - bis C 24 -Alkyl oder C 6 - bisnC 24 -Alkenyl R 4 Wasserstoff R 5 , R 6 a) gemeinsam C 4 - bis C 10 -Alkandiyl, b) jeweils C 2 - bis C 10 -Alkyl, C 5 - bis C 8 -Cycloalkylnoder C 7 - bis C 20 -Aralkyl, c) jeweils ein hydroxylterminiertes Poly-(C 2 - bisnC 4 -alkylenoxid), oder d) ein Rest R 5 oder R 6 die unter (a) bis (c) angegebenenBedeutung und der andere Rest Wasserstoffnoder ein Rest der Formel IIn nin der X C 2 - bis C 6 -Alkandiyl bedeutet und R 7 gleichbedeutend ist mit R 5 oder R 6 mit der Ausnahme,ndaß R 7 nicht ein Rest der Formel II bedeutet, nwobei n die Reste R 5 und R 6 in jedem der Fälle (a) bis (d) insgesamtneine (1) an ein aliphatisches C-Atom gebundene Hydroxylgruppenntragen, gegebenenfalls der Rest R 5 und/oder R 6 1 oder 2 aromatischngebundene Hydroxylgruppen oder 1 Nitril-, tertiäre Amino-,nCarbonsäure- oder Sulfonsäuregruppe, die gegebenenfalls innForm ihrer Salze vorliegen, trägt, und die mittlere Funktionalität (F) aller Aufbaukomponenten desnPolyurethans (A), bezogen auf die Funktionalitäten, die beimnAufbau des Polyurethans (A) in einer Additionsreaktion miteinandernreagieren, 1,5 bis 2,2 beträgt. Aqueous dispersions containing a polyurethane (A) with structural units which differ from compounds of the formula (I) in which the substituents have the following meaning: R 1 , R 2 , R 3 in each case hydrogen, C 1 - to C 24 -alkyl or C 6 - to C 24 -alkenyl R 4 hydrogen R 5 , R 6 a) together C 4 - to C 10 -alkanediyl, b) in each case C 2 to C 10 alkyl, C 5 to C 8 cycloalkyl or C 7 to C 20 aralkyl, c) in each case a hydroxyl-terminated poly (C 2 - to C 4 -alkylene oxide), or d) a radical R 5 or R 6 has the meaning given under (a) to (c) and the other radical is hydrogen or a radical of the formula II in the X C 2 - to C 6 -alkanediyl means and R 7 is equivalent to R 5 or R 6 with the exception that R 7 does not represent a radical of the formula II, in which the radicals R 5 and R 6 in each of cases (a) to (d) carry a total of one (1) hydroxyl groups bonded to an aliphatic carbon atom, optionally the radical R 5 and / or R 6 carries 1 or 2 aromatically bound hydroxyl groups or 1 nitrile, tertiary amino, carboxylic acid or sulfonic acid group, which are optionally present in the form of their salts, and the average functionality (F) of all structural components of the polyurethane (A), based on the functionalities which react with one another during the synthesis of the polyurethane (A) in an addition reaction, is 1.5 to 2.2.

专利号:EP-3177589-A1
优先权日:2014-08-06
标题 :Method for the synthesis of mirabegron and its derivatives