CAS: 51576-04-6; L-Isoleucic Acid

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CAS号1460-34-0 3-甲基-2-氧代戊酸 | CAS号95-14-7 苯并三氮唑 | CAS号1374640-37-5 N-[2-(4-hydroxy...

合成工艺路线路线简述

    📜(S)-2-甲基丁醛置于palladium On Activated Charcoal Sodium Hydroxide,Sodium Azide,硫酸,氢气,Sodium Nitrite体系中,用 甲醇,乙二醇二甲醚,乙酸乙酯,N,N-二甲基甲酰胺 作为反应溶剂,-10.0~25.0 °C,101.33 Kpa 条件下,反应 62.0H,反应生成 (2S3S)-2-羟基-3-甲基戊酸
    参考文献:Lloyd-Williams,Paul; Monerris,Patricia; Gonzalez,Isabel,Journal Of The Chemical Society. Perkin Transactions I,1994,# 14,P. 1969-1974
    标题:Lloyd-Williams,Paul; Monerris,Patricia; Gonzalez,Isabel,Journal Of The Chemical Society. Perkin Transactions I,1994,# 14,P. 1969-1974

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    专利信息


    专利号:US-6380156-B1
    优先权日:1996-10-24
    标 题:Total synthesis of the amino hip analogue of didemnin A
    发明人:RINEHART KENNETH L; KATAUSKAS ALEXANDRA J
    权利人:UNIV ILLINOIS
    摘要:Disclosed is a synthetic method for the preparation of analogs of Didemnin A (1), particularly the Amino-Hip analog of Didemnin A, also known as 'AipDidemnin A' (8). These compounds have the following structures:

    专利号:JP-2001504814-A
    优先权日:1996-10-24
    标题:Total Synthesis of Amino Hip Analogs of Didemnin A

    专利号:WO-9817302-A1
    优先权日:1996-10-24
    标题:Total synthesis of the amino hip analogue of didemnin a

    专利号:US-11787900-B2
    优先权日:2021-11-08
    标题 :Biodegradable sustainable polyesters
    发明人:PRATHER KRISTALA L JONES; PLATA DESIREE; OLSEN BRADLEY D; JOO WONTAE; AV-RON SARAH; BANNISTER K'YAL RASEAN; TANTAWI OMAR
    权利人:MASSACHUSETTS INST TECHNOLOGY
    摘要:Disclosed is a copolymer comprising a hydroxyacid, wherein the copolymer is biodegradable with a decomposition temperature is substantially higher than its melting temperature. Also disclosed is a method of synthesis of a poly(pivalolactone-co-caprolactone) copolymer.

    专利号:DE-69723728-T2
    优先权日:1996-10-24
    标题:TOTAL SYNTHESIS OF THE AMINO HIP ANALOG OF DIDEMNIN A

    专利号:US-3047585-A
    优先权日:1960-10-28
    标题 :Synthesis of 3-indolealkanoic acids
    发明人:JOHNSON HERBERT E
    权利人:UNION CARBIDE CORP

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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Facile Synthesis Of α-Hydroxy Carboxylic Acids From The Corresponding α-Amino Acids
    作者:Nicolai Stuhr-Hansen,Shahrokh Padrah,Kristian Strømgaard |发布日期:2014.7
    摘要:Procedure Is Developed For The Synthesis Of α-Hydroxy Carboxylic Acids By Treatment Of The Corresponding Protonated α-Amino Acid With Tert-Butyl Nitrite In 1,4-Dioxane-Water. The Amino Moiety Must Be Protonated And Located α To A Carboxylic Acid Function In Order To Undergo Initial Diazotization And Successive Hydroxylation, Since Neither β-Amino Acids Nor Acid Derivatives Such As Esters And Amides Undergo

    合成参考文献


    参考文献:10.1007/s11274-017-2337-z
    摘要:Jiang H, Ji C, Sui J, Sa R, Wang X, Liu X, Guo TL. Antibacterial and antitumor activity of Bogorol B-JX isolated from Brevibacillus laterosporus JX-5. World Journal of Microbiology and Biotechnology. 2017 Sep 18;33(10):177. doi: 10.1007/s11274-017-2337-z.
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