CAS: 476-28-8; (1S,2S,3A1S,12Bs)-2,3A1,4,5,7,12B-Hexahydro-1H-[1,3]Dioxolo[4,5-J]Pyrrolo[3,2,1-De]Phenanthridine-1,2-Diol

上下游产品

CAS号69787-57-1 1-acetyl-2-chlo... | CAS号2492-05-9 1,2-Diacetoxyly... | CAS号6391-78-2 (1S,2S,3a(1)S,1... | CAS号7344-73-2 1-Acetoxylycorine | CAS号58700-92-8 1α-hydroxy-9,10... | CAS号58700-89-3 α-dihydrolycori... | CAS号58700-93-9 (1S,2S,3a(1)S,1... | CAS号71635-31-9 9,10-methanediy... | CAS号40360-71-2 Anhydrolycorinone | CAS号641-89-4 anhydrolycorine | CAS号40141-98-8 5-methyl-[1,3]d...

📜1α-Hydroxy-9,10-Methanediyldioxy-Galanth-2-En-7-One置于lithium Aluminium Tetrahydride,间氯过氧苯甲酸体系中,用 四氢呋喃,吡啶,氯仿 作为反应溶剂,化学反应生成 石蒜碱
参考文献:Tsuda,Y. Et Al.,Journal Of The Chemical Society. Perkin Transactions I,1979,P. 1358-1363
标题:Tsuda,Y. Et Al.,Journal Of The Chemical Society. Perkin Transactions I,1979,P. 1358-1363

专利信息

专利号:WO-2023241716-A1
优先权日:2022-06-16
标 题 :Method for inducing in-situ regeneration of mammal and use thereof
发明人：LI WEI; ZHOU QI; He zheng-quan; YUAN XUEWEI; LU ZONGBAO; WANG XIN; WANG SHUAI; LI YUFEI; WANG LIU
权利人:INST ZOOLOGY CAS; BEIJING INST FOR STEM CELL AND REGENERATIVE MEDICINE
摘要:Provided is use of a protein synthesis inhibitor in promoting regeneration and repair capacity of mammal tissues or complex structures or organs. The protein synthesis inhibitor is a small molecule compound, from any of cycloheximide or an Amaryllidaceae extract, capable of promoting regeneration of mammal tissues and organs.

专利号:US-4214092-A
优先权日:1979-02-21
标题:Rearrangement of acyloxy furans and thiophenes prepared from butenolides
发明人：KRAUS GEORGE A
权利人:UNIV IOWA STATE RES FOUND INC
摘要:A method of preparing acyloxy furans and thiophenes from butenolides comprising reacting a pre-selected butenolide with an acylating agent in the presence of a base to provide an acyloxy furan intermediate, which in turn undergoes rearrangement in the presence of Lewis Acids by cleavage of a carbon-oxygen bond, and addition of the cleaved moiety to the furan ring forming a carbon-carbon bond on the ring. The result is a heretofore unknown group of lactone type compounds which are biologically active, in and of themselves, and in addition offer use as versatile synthesis intermediates to achieve, by conventional synthesis methods heretofore unavailable compounds.

专利号:WO-2009140467-A1
优先权日:2008-05-15
标 题:Oxobenzindolizinoquinolines and uses thereof
发明人：CUSHMAN MARK S; CINELLI MARIS A; MORRELL ANDREW E; POMMIER YVES G
权利人:PURDUE RESEARCH FOUNDATION; CUSHMAN MARK S; US GOV HEALTH & HUMAN SERV; CINELLI MARIS A; MORRELL ANDREW E; POMMIER YVES G
摘要:The synthesis of aromathecins, substituted 12 H -5,l la-diazadibenzo[ b,h ]fluoren- 11 -ones is described. Use of these cytotoxic compounds and pharmaceutical compositions containing them for the treatment of cancer is described. Two novel processes for the synthesis of this system and a series of 14-substituted aromathecins as novel cytotoxic, topoisomerase I poisons are described.

专利号:US-2001024798-A1
优先权日:1998-06-11
标题:Biomimetic combinatorial synthesis
发明人：SHAIR MATTHEW D; LINDSLEY CRAIG W; PELISH HENRY E; SHEEHAN SCOTT M; GOESS BRIAN C; LAYTON MARK E; CHAN LAWRENCE K; CHEN CHUO; WESTWOOD NICHOLAS J
摘要:The present invention provides biomimetic compounds and libraries thereof, as well as methods for their production. In general, the inventive method involves the selection of a desired biological synthetic pathway and mimics that synthetic pathway utilizing modern synthetic tools. The structures formed from this method are preferably generated in fewer than four steps. These scaffold structures can then be functionalized to yield biomimetic compounds and libraries of compounds. In preferred embodiments, biomimetic compounds and libraries are generated from an oxidative phenolic coupling reaction. In other particularly preferred embodiments, the compounds and libraries of compounds are generated from cascade reactions to yield bicyclo [n. 3.1 ] ring systems, medium ring systems, and fused ring systems. In addition to compounds, libraries and methods for their production, the present invention also provides pharmaceutical compositions and methods and kits for determining one or more biological activities of the library members.

专利号:WO-2023241717-A1
优先权日:2022-06-16
标题:Substance for promoting regeneration and repair of organs of mammals and use thereof
发明人：LI WEI; ZHOU QI; He zheng-quan; LU ZONGBAO; WANG SHUAI; WANG XIN; YUAN XUEWEI; WANG LIU
权利人:INST ZOOLOGY CAS; BEIJING INST FOR STEM CELL AND REGENERATIVE MEDICINE
摘要:Provided is use of a substance capable of up-regulating ISG gene expression in preparing a drug or reagent for promoting the regeneration and repair capacity of tissues or complex structures or organs of mammals. The substance for up-regulating ISG gene expression is selected from one or two or more of an MAPK inhibitor, a retinoic acid receptor-related orphan receptor inhibitor, a protein synthesis inhibitor, and an interferon (IFNγ, β, λ) or alarmin (S100A8/A9) protein. The regeneration and repair refer to promoting the regeneration of tissues or complex structures or organs after tissue or organ resection or damage.

专利号:US-2011212986-A1
优先权日:2008-08-21
标题 :Anti-flavivirus therapeutic
发明人：SHI PEI-YONG; PUIG-BASAGOITI FRANCESC; PANKIEWICZ KRZYSZTOF W; FELCZAK KRZYSZTOF; CHEN LIQIANG
权利人:HEALTH RESEARCH INC; UNIV MINNESOTA
摘要:The present invention relates to anti-flavivirus compounds, including lycorine and derivatives thereof, and their use in treating a subject infected by a flavivirus. The present invention also relates to the use of the anti-flavivirus compounds for the prophylaxis of flavivirus infection. The present invention further relates to a method of suppressing viral RNA synthesis of a flavivirus. Also described is a method of preparing an anti-flavivirus compound for use in the treatment or prophylaxis of flavivirus infection.