专利号:US-4617409-A 优先权日:1984-06-29 标题 :Aminomethyltriorganotin compounds, preferably α-mono or disubstituted; and the method of preparation 发明人:ELISSANDO BERNARD; PEREYRE MICHEL; QUINTARD JEAN-PAUL 权利人:CENTRE NAT RECH SCIENT 摘要:The invention concerns a method of preparation of aminomethyltriorganotin compounds, preferably α-mono or disubstituted, the new tin compounds obtained thereby and an application of said tin compounds to the synthesis of aminomethylorganometallic compounds and to the regiospecific preparation of β-aminoalcohols. The intermediate tin and metallic compounds are new. The method for preparing the tin compounds comprises reacting an iminium salt with a corresponding stannylanion, preferably a triorganostannylanion. This method provides best yields and provides regiospecific β-aminoalcohols useful by having in most cases a large spectrum of pharmacological activities.