专利号:US-5272138-A 优先权日:1988-02-12 标 题:Naturally occurring gangliosides containing de-N-acetyl-sialic acid and their applications as modifiers of cell physiology 发明人:HAKOMORI SEN-ITIROH; NORES GUSTAVO A; HANAI NOBUO; DOHI TAEKO; LEVERY STEVEN B; SALYAN MARY ELLEN K; NOJIRI HISAO 权利人:BIOMEMBRANE INST 摘要:A method for preparing de-N-acylated forms of an N-acyl sugar-containing glycosphingolipid and lyso forms of glycosphingolipid comprising hydrolyzing the glycosphingolipids under mild alkaline conditions such that the N-acyl group of the sugar moiety is preferentially hydrolyzed. Substantially pure gangliosides containing de-N-acetyl-sialic acid isolated from natural sources. A culture medium for stimulating growth of human and animal cells comprising: essential nutrients for cell growth, and a cell growth stimulatory amount of one or more gangliosides containing de-N-acetyl-sialic acid. A method for stimulating growth of human and animal cells cultured in vitro with a cell growth stimulatory amount of one or more gangliosides containing de-N-acetyl-sialic acid. A medicament and method for stimulating or inhibiting growth of human and animal cells by stimulating or inhibiting the production of growth stimulators selected from the group consisting of gangliosides containing de-N-acetyl-sialic acid, substances that promote synthesis of gangliosides containing de-N-acetyl-sialic acid and pharmaceutically acceptable salts thereof.
专利号:WO-2004084827-A2 优先权日:2003-03-21 标 题:Reduction of zinc-induced neurotoxic injury by blockade of nitric oxide synthesis
专利号:CN-104640447-B 优先权日:2012-07-24 标 题:Contains 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or its derivatives and inhibits VLCFA synthesis and fatty acids/lipids Herbicidal compositions of synthetic herbicides
1. Carere A, Ortali VA, Cardamone G, Morpurgo G. Mutagenicity of dichlorvos and other structurally related pesticides in Salmonella and Streptomyces. Chem Biol Interact. 1978 Sep;22(2-3):297-308. doi: 10.1016/0009-2797(78)90134-5.
合成参考文献
摘要:Farm Chemicals Handbook., -(C161), 1991 摘要:Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966., -(817), 1966 摘要:Pesticide Index, Frear, E.H., ed., State College, PA, College Science Pub., 1969, 5(167), 1976