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专利信息
专利号:WO-2023105497-A1
优先权日:2021-12-10
标题:Synthesis of glp-1 analogues
发明人:GODHA ATUL KASTURCHAND; NARAYANASWAMY SATHYA VANGANUR; BHAGYARAJ ARETI VENKATA; BAVADEKAR ASLAM JAHANGIR; LAKSHMANAPPA RUDRESH; NAGOOR SHEIKSYEDALI; MURUGAN RANJITHKUMAR; GADAKH AMOL VASANTRAO; SAMBASIVAM GANESH
权利人:ANTHEM BIOSCIENCES PVT LTD
摘要:The present invention provides a method of preparation of GLP-1 peptides by using different peptide fragments having amino acid sequences SEQ ID NO:1 (Fragment IG), SEQ ID NO:2 (Fragment SG), Fragment BG, SEQ ID NO:3, and SEQ ID NO:4 5 and combinations thereof. The method of preparation is environmentally benign, simple, straightforward, and efficient and provides the end product in high yield and purity. The purification method of the peptides is also described.
专利号:CN-113444164-B
优先权日:2021-06-29
标题 :A kind of method for solid-phase synthesis of semaglutide
专利号:WO-2024156694-A1
优先权日:2023-01-24
标 题:Method for synthesizing polypeptides
发明人:GLAFFIG MARKUS; HENNIG RABEA; HANSEN ANNA METTE; FOMSGAARD JENS; PAWLAS JAN
权利人:BOEHRINGER INGELHEIM INT
摘要:The present invention relates to a method for synthesizing a polypeptide based on solid phase peptide synthesis, the polypeptide comprising a backbone, the backbone comprising one amino acid moiety Δ selected from diamino alkanoic acids comprising from 3 up to 10 carbon atoms and one peptide side chain covalently attached to the amino acid moiety Δ, the amino acid moiety Δ being coupled to an amino acid moiety W of the backbone, the method comprising at least one reaction cycle comprising providing an amino acid building block, activating the amino acid building block in absence of a solid phase at a defined temperature and time period, and coupling the amino acid building block to the backbone.
专利号:CN-112010961-B
优先权日:2019-05-31
标题 :A kind of solid-liquid synthesis method of semaglutide
专利号:CN-119823233-A
优先权日:2025-03-18
标题:Synthesis method of retaglutide and retaglutide
专利号:CN-116120427-B
优先权日:2023-01-30
标题 :Semex lattice Synthesis method of lupeptide