CAS: 14376-79-5; 3,3,5,5-Tetramethylcyclohexanone

相似化合物

2979-19-3 126-81-8 2320-30-1

上下游产品

3,5,5-Trimethylcyclohex-2-en-1-one methylmagnesium bromide ethanol 1-hydroxy-3,3,5,5-tetramethyl-cyclohexanecarbonitrile 1,3,3,5,5-pentamethylcyclohexanol hydroxymethylene-2 tetramethyl-3,3,5,5 cyclohexanone-1 3,3,5,5-tetramethyl cyclohexanol 2-bromo-3,3,5,5-tetramethylcyclohexanone

📜1,3,3-Trimethyl-Bicyclo<4.1.0>Heptanon-(5)置于n,N-二甲基丙烯基脲,Samarium Diiodide体系中,用 四氢呋喃 用作溶剂,化学反应 0.08H,以34%的收率获得3,3,5,5-四甲基环己酮
参考文献:双环[4.1.0]酮的一些新型电子转移介导的级联开环反应
标题:双环[4.1.0]酮的一些新型电子转移介导的级联开环反应
摘要:描述了由碘化sa(II)和其他电子转移剂介导的环丙基酮的自由基开环反应.该策略允许串联重排环化反应以及通过各种亲电试剂捕获所得resultant(III)烯醇化物,以构建复杂的双环系统.
Doi:10.1016/0040-4020(96)00635-7

专利信息

专利号:US-4895996-A
优先权日:1988-10-17
标 题 :Synthesis of alkenes from enamines via hydroboration
发明人：GORALSKI CHRISTIAN T; SINGARAM BAKTHAN; BROWN HERBERT C
权利人:PURDUE RESEARCH FOUNDATION; DOW CHEMICAL CO
摘要:Alkenes are prepared by the hydroboration of enamines followed by an elimination reaction to form the alkene. This process has wide applicability and is useful for the stereospecific synthesis of [Z] isomers. It is preferred to use 9-borabicyclo[3.3.1 nonane as the hydroborating agent and to use methanol to catalyze the elimination reaction.

专利号:US-8759581-B2
优先权日:2009-06-29
标 题 :Method of preparing 1-chloroacetamido-1,3,3,5,5-pentamethylcyclohexane
发明人：KOLLER HERBERT; PYERIN MICHAEL
权利人:KOLLER HERBERT; PYERIN MICHAEL; MERZ PHARMA GMBH & CO KGAA
摘要:Method of preparing 1-chloroacetamido-1,3,3,5,5-pentamethylcyclohexane, an intermediate in the synthesis of 1-amino-1,3,3,5,5-pentamethylcyclohexane (Neramexane) or a pharmaceutically acceptable salt thereof, comprising step (iii):n (iii) reacting 1-hydroxy-1,3,3,5,5-pentamethylcyclohexane with chloroacetonitrile in the presence of an acid,n nwherein 1-hydroxy-1,3,3,5,5-pentamethylcyclohexane is employed in step (iii) as obtained in the reaction of a methylmagnesium halide with 3,3,5,5-tetramethylcyclohexanone without having been subjected to a purification step.

专利号:US-5908944-A
优先权日:1991-09-27
标题 :Methylation or ethylation agent and process for 1,4-addition of a methyl or ethyl group to an α, β-unsaturated keto compound
发明人：WESTERMANN JUERGEN; NICKISCH KLAUS
权利人:SCHERING AG
摘要:This invention describes a new methylation or ethylation agent containing trimethyl aluminum or dimethyl zinc or triethyl aluminum as methyl or ethyl source, which additionally contains catalytic amounts of one or more copper(I) and/or copper(II) compounds as well as a process for the 1,4-addition of a methyl or ethyl group to an α,β-unsaturated or an α,β-double unsaturated ketone or an α,β-unsaturated aldehyde using the agent according to the invention. n By using only catalytic amounts of copper and a CKW (chlorinatedhydrocarbon)-free reaction medium, the new methylation/ethylation agent/process is distinguished by its environmental compatibility and it is, for example, suitable for the production of initial products for the synthesis of biologically effective compounds.

专利号:US-8784847-B2
优先权日:2009-04-17
标 题 :Synthesis of 1-amino-1,3,3,5,5,-cyclohexane mesylate
发明人：HENRICH MARKUS; NEGURA SIMONA; TASI GERGELY; KOCSAN PAL; SBROGIO FEDERICO; PYERIN MICHAEL; KOLLER HERBERT
权利人:HENRICH MARKUS; NEGURA SIMONA; TASI GERGELY; KOCSAN PAL; SBROGIO FEDERICO; PYERIN MICHAEL; KOLLER HERBERT; MERZ PHARMA GMBH & CO KGAA
摘要:Process for manufacturing 1-amino-1,3,3,5,5-pentamethylcyclohexane mesylate comprising step (i):n (i) reacting 1-amino-1,3,3,5,5-pentamethylcyclohexane with methane sulfonic acid in a solvent or a mixture of two or more solvents selected from anisole, cumene, pentane, hexane, heptane, isooctane, methyl acetate, propyl acetate, isopropyl acetate, n-butyl acetate, isobutyl acetate, methyl ethyl ketone, methyl isopropylketone, methyl isobutyl ketone, dimethyl sulphoxide, tetrahydrofuran, methyltetrahydrofuran, 1,1-diethoxypropane, 1,1-dimethoxymethane, and 2,2-dimethoxypropane.

专利号:JP-6076736-B2
优先权日:2009-04-17
标 题:Synthesis of 1-amino-1,3,3,5,5-pentamethylcyclohexane mesylate

专利号:US-2012100184-A1
优先权日:2009-04-17
标 题 :Synthesis of 1-amino-1,3,3,5,5,-cyclohexane mesylate