CAS: 14221-48-8; Ammonium Hexacyanoferrate(3-)

专利信息

专利号:WO-2024059703-A1
优先权日:2022-09-16
标题:Covalently modified template-independent dna polymerase and methods of use thereof
发明人：SPRACHMAN MELISSA M; BRYAN CASSIE M; GRISWOLD JR; DOE ROBERT E; MORAN ISAAC; RECORDS WILLIAM C; MAGYAR ANDREW P; RODRIGUEZ JUAN CARLOS; COLEMAN RACHEL; DOYLE ROBERT
权利人:CHARLES STARK DRAPER LABORATORY INC
摘要:Provided herein are engineered terminal deoxynucleotidyl transferase (TdT) proteins with certain modifications, including mutations to confer thermal stability and to install an exposed amino acid residue to which a small molecule can be covalently tethered via bioconjugate chemistries such as click chemistry. Also provided herein are methods of nucleic acid molecule synthesis using engineered TdTs and nucleotide molecules attached to redox-cleavable linkers, wherein the engineered TdT incorporates the nucleotide molecule into a nucleic acid strand and is separated from the nucleotide molecule when the redoxcleavable linker is cleaved upon exposure to suitable electrochemical conditions. Also provided herein are engineered TdTs covalently attached to a nucleotide molecule via a tether and also nucleotide molecules comprising a redox-cleavable linker. Further provided herein are systems for enzymatic DNA synthesis comprising an engineered TdT, a redox-cleavable linker a redox shuttle solution, and two or more electrodes.

专利号:US-2004063568-A1
优先权日:2000-10-26
标题 :Method for the production of form-selective catalysts and use thereof
发明人：KUHNLE ADOLF; DUDA MARK; SEELBACH KARSTEN; HASENZAHL STEFFEN; TANGER UWE; JOST CARSTEN; KLEMM ELIAS; REITZMANN ANDREAS
摘要:The invention relates to a process for manufacturing zeolite catalysts containing subgroup metals by hydrothermal synthesis with subsequent calcination, which is characterized in that the subgroup metals are used in hydrothermal synthesis in the form of carbonyl, isonitrile or cyanocomplexes. n The catalysts thus produced can be used as a catalyst for removing nitrogen or for oxidizing organic compounds.