3-氯丙基三乙氧基硅烷 以 N-甲基乙酰胺 用作溶剂,以84.3%的收率获得4-三乙氧基硅基丁腈 参考文献:Method And Apparatus For The Preparation Of Cyanoalkyl-Alkoxysilanes 标题:Method And Apparatus For The Preparation Of Cyanoalkyl-Alkoxysilanes 摘要:一种制备氰基烷基烷氧基硅烷的方法,适用于大规模技术生产这些硅烷,即在溶剂存在下,氯烷基烷氧基硅烷与碱金属氰化物反应,在带有装载这些原料的手段和碱金属氯化物副产物的出口开口的搅拌反应器中进行,该反应器通过旁通阀门连接到具有叠加冷凝器的柱中.在反应器中的反应结束后,首先通过柱蒸馏出溶剂,然后蒸馏出主要部分的氰硅烷,然后通过旁路绕过柱蒸馏出剩余的氰硅烷.然后通过锁将碱金属氯化物从反应器中移除.
专利信息
专利号:WO-2023237381-A1 优先权日:2022-06-09 标题:Process for the synthesis of polyethylenes or copolymers of ethylene and 1,3-diene having a terminal ketone function 发明人:BOISSON CHRISTOPHE; D'AGOSTO FRANCK; DESGRANGES ARIANE; NGO ROBERT; JEAN-BAPTISTE-DIT-DOMINIQUE FRANÇOIS 权利人:MICHELIN & CIE; CENTRE NAT RECH SCIENT; ECOLE SUPERIEURE DE CHIMIE PHYSIQUE ELECTRONIQUE LYON; UNIV CLAUDE BERNARD LYON 摘要:The invention relates to a method for preparing a polyethylene having a terminal ketone function or a copolymer of ethylene and a 1,3-diene and optionally a vinyl aromatic compound which contains more than 50 mol% of ethylene and has a terminal ketone function; said method comprises a polymerization reaction of the monomers in the presence of a borohydrido-neodymocene complex and an organo-magnesium compound, followed by a coupling reaction with a compound having a nitrile function, and then a hydrolysis reaction.
专利号:US-10195599-B2 优先权日:2013-06-25 标题:Synthesis of functionalized carbon microspheres and their catalyst activity in C—O and C—N bond formation reactions 发明人:BIRADAR ANKUSH VENKATRAO; UMBARKAR SHUBHANGI BHALCHANDRA; DONGARE MOHAN KERABA 权利人:COUNCIL SCIENT IND RES 摘要:Disclosed herein is a simple process for functionalization/grafting of carbon microspheres obtained from bagasse with various active functional groups onto it and use of the same as catalyst for various organic reactions, having very high selectivity and conversion rate.
专利号:US-7815883-B2 优先权日:2008-12-23 标题:Preparation of organic-functionalized mesoporous silica with platelet morphology and short mesochannels 发明人:CHENG SOOFIN; CHEN SHIH-YUAN; CHEN CHIN-CHANG 权利人:UNIV NAT TAIWAN 摘要:A facile synthesis route for preparing SBA-15 silica of platelet shape and very short mesochannels was developed by introducing a small amount of Zr(IV) ions in the first synthesis solution. The synthesis route can be easily extended to prepare SBA-15 materials with various organic functional groups in one pot.
专利号:WO-03068806-A1 优先权日:2002-02-14 标 题 :Solid phase peptide synthesis on silica 发明人:GROARKE MICHELLE 权利人:JOHNSON MATTHEY PLC; GROARKE MICHELLE 摘要:A method for peptide synthesis is described, comprising steps of forming an organofunctional silica by reaction of an alkyl silicate, an organofunctional silane and water, optionally in the presence of a template compound; removing the template compound if present; reacting said organofunctional silica with a first protected amino acid to produce a tethered protected amino acid; deprotecting the tethered protected amino acid; reacting at least one further protected amino acid with said tethered deprotected amino acid to form a tethered peptide, and removing the peptide from the organofunctional silica. Preferably, prior to reaction of the first protected amino acid, the organofunctional silica is reacted with at least one linking compound to form a linker-modified organofunctional silica with which the first protected amino acid is reacted. A method for preparing an organfunctional silica by the co-hydrolysis of an alkyl silicate and an organofunctional silane is depicted below. The wavy line represents the silicon atom on or within the resulting silica material formula (I). A reaction of a protected amino acid with an organofunctional silica to provide a tethered protected amino acid is depicted below formula (II).
专利号:US-6177534-B1 优先权日:1997-12-23 标题 :Silylated resins and the synthesis thereof 发明人:ANTONUCCI JOSEPH M; STANSBURY JEFFREY W; FOWLER BRUCE O 权利人:US COMMERCE 摘要:A silylated resin suitable for use as an adhesive binder for composites and in sealant and adhesive dental applications is represented by the general formula (I): n in which: n R 1 is an aliphatic, cycloaliphatic, aryl, hydrocarbon, or fluorocarbon group; n R 2 is the same as R 1 or a different aliphatic, cycloaliphatic, aryl, hydrocarbon, or fluorocarbon group; n M 2 is the same as M 1 or a different functional or nonfunctional group selected from the group consisting of: n n is 1-3; n x is 1-20; and n y is 1-20; n which comprises the reaction product of the exchange reaction of a hydroxylated, aminated, or carboxylated acrylic resin represented by the general formula (II): n in which: n R 4 is an aliphatic, cycloaliphatic, aryl, hydrocarbon, or fluorocarbon group with one or more protic functional groups selected from the group consisting of: n n n OH, N—H, and CO 2 H n n n R 5 is H or CH 3 ; and n R 6 is H or CH 3 ; n with a trialkoxyorganosilane or triacyloxyorganosilane represented by the general formula (III): n in which: n R 7 , R 8 , and R 9 each is: n R 10 is an aliphatic, or aryl group which can optionally be substituted with a group from the group of an acrylic group, a methacrylic group, an epoxy group, and a substituted amino, hydroxyl, or carboxylic acid group such as an ester or an amide.
专利号:WO-2019218027-A1 优先权日:2018-05-18 标题:Core-shell particles 发明人:MEANEY SHANE; TABOR RICHARD; FOLLINK BART 权利人:UNIV MONASH 摘要:The application relates to a core-shell particle having a) a cross-linked polyelectrolyte core, and b) a silica-based shell having covalently bound thereto one or more groups of formula –R–F, wherein R is an organic group and F is a functional moiety. The application also relates to a method of synthesis of a core-shell particle, the method comprising the steps of: a) providing a cross-linked polyelectrolyte core template, b) coating the core template with a silica-based shell, and c) introducing one or more groups of formula –R–F covalently bound to the silica-based shell, wherein R is an organic group and F is a functional moiety.
[参考文献]: Diego Soares Domingues, Et Al. Analysis Of Drugs In Plasma Samples From Schizophrenic Patients By Column-Switching Liquid Chromatography-Tandem Mass Spectrometry With Organic-Inorganic Hybrid Cyanopropyl Monolithic Column. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Jul 1:993-994:26-35.
合成参考文献
摘要:Corcé, V.; Lévêque, C.; Ollivier, C.; Fensterbank, L., Science of Synthesis: Photocatalysis in Organic Synthesis, (2018) 1, 433.