CAS: 103962-05-6; 1-Iodo-4-(Trifluoromethoxy)Benzene

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专利信息

专利号:US-7884125-B2
优先权日:2008-04-30
标 题:Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues
发明人：STEVENS CHRISTIAN; HEUGEBAERT THOMAS
权利人:UNIV GENT
摘要:The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction.

专利号:WO-0009116-A1
优先权日:1998-08-14
标 题:Grp receptor ligands
发明人：XIANG JIA-NING; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
权利人:SMITHKLINE BEECHAM CORP; XIANG JIA NING; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
摘要:Novel GRP receptor antagonists are provided. Methods of using the present compounds to antagonize GRP receptors are also provided. The present invention further involves the synthesis of the present compounds.

专利号:US-2009275616-A1
优先权日:2008-04-30
标 题 :Straightforward entry to 7-azabicyclo[2.2.1]heptane-1-carbonitriles and subsequent synthesis of epibatidine analogues

专利号:WO-0009115-A1
优先权日:1998-08-14
标 题 :Grp receptor ligands
发明人：XIANG JIA-NING; OSIFO IRENNEGBE KELLY; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
权利人:SMITHKLINE BEECHAM CORP; XIANG JIA NING; OSIFO IRENNEGBE KELLY; KARPINSKI JOSEPH M; CHRISTENSEN SIEGFRIED B IV
摘要:Novel GRP receptor antagonists are provided. Methods of using the present compounds to antagonize GRP receptors are also provided. The present invention further involves the synthesis of the present compounds.

专利号:CN-114213300-B
优先权日:2022-01-07
标 题:Mechanochemical synthesis of organic selenium compound

专利号:CN-114213300-A
优先权日:2022-01-07
标 题 :Mechanochemical synthesis of organic selenium compound