专利号:US-2025188083-A1 优先权日:2021-06-25 标 题:Modulators of Histone Acetyltransferase 1 and Methods of Treatment Thereof 发明人:GRUBER JOSHUA JAMES; LIPCHIK ANDREW; SNYDER MICHAEL P; SCHOW STEVEN R 权利人:UNIV LELAND STANFORD JUNIOR 摘要:Small molecules compounds and methods of their synthesis are provided. Small molecules identified can inhibit histone acetyltransferase 1 activity. Formulations and medicaments are also provided that are directed to the treatment of human disorders and conditions, such as, for example, neoplasms, cancers, viral, fungal, and parasitic infections, and aging. Therapeutics are also provided containing a therapeutically effective dose of one or more small molecule compounds, present either as pharmaceutically effective salt or in pure form, including, but not limited to, formulations for oral, intravenous, or intramuscular administration.
专利号:CN-114539039-B 优先权日:2022-03-08 标题:A method for the synthesis of chiral fluorophenylethyl alcohol through photo-enzyme catalysis
专利号:WO-03061385-A1 优先权日:2002-01-17 标题:Tricyclic nucleoside library compounds, synthesis, and use as antiviral agents 发明人:AN HAOYUN; HONG ZHI; SMITH KENNETH; DING YILI; GIRARDET JEAN-LUC 权利人:RIBAPHARM INC; AN HAOYUN; HONG ZHI; SMITH KENNETH; DING YILI; GIRARDET JEAN-LUC 摘要:Tricyclic nucleoside libraries and library compounds are prepared using combinatorial chemistry and non-combinatorial chemistry methods. Contemplated library compounds are particularly useful in inhibition of viral propagation, and particularly of viral propagation of the HCV virus.
专利号:WO-0244214-A1 优先权日:2000-11-29 标题 :Methods for the synthesis of a modified hemoglobin solution
专利号:WO-0246372-A1 优先权日:2000-12-08 标 题 :Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
专利号:PT-103828-A 优先权日:2007-09-21 标题:NANOMAGNETE-PORFIRIN HYBRID MATERIALS, PROCESS FOR ITS SYNTHESIS AND THEIR APPLICATION IN FORMULATIONS FOR DISINFECTION OF WATERS
参考文献:10.4061/2010/645150 摘要:Samanta S, Haldar S, Ghosh TK. Comparative Efficacy of an Organic Acid Blend and Bacitracin Methylene Disalicylate as Growth Promoters in Broiler Chickens: Effects on Performance, Gut Histology, and Small Intestinal Milieu. Veterinary Medicine International. 2010;2010():1–8. doi: 10.4061/2010/645150.