CAS: 6459-59-2; Histidine Hydrochloride

该化合物是一种氨基酸丁的盐,其特征是其基本特性,因为存在一个伊米达佐尔侧链.该化合物一般被作为白色晶状粉,在水中溶解,适合各种生化用途.该化合物在蛋白合成中起着关键作用,并参与酶催化,作为肝胺的前体,一种重要的...

结构式图片

相似化合物

123333-71-1 109425-51-6 135610-90-1

上下游产品

CAS号645-35-2 L-组氨酸盐酸盐 | CAS号18502-05-1 4(5)-氰甲基咪唑 | CAS号645-35-2 L-组氨酸盐酸盐 | CAS号6341-24-8 D-组胺盐酸盐一水合物

合成工艺路线路线简述

    📜L-组氨酸盐酸盐置于水杨醛体系中,用 溶剂黄146 作为反应溶剂,化学反应 1.0H,以100%的收率获得产物组氨酸甲酯
    参考文献:Method For The Racemization Of Optically Active Amino Acids
    标题:Method For The Racemization Of Optically Active Amino Acids
    摘要:
    DOI:10.1021/jo00154A019

    海关参考信息

    专利信息


    专利号:US-6620942-B2
    优先权日:1998-12-23
    标题 :Synthesis of histamine dihydrochloride
    发明人:YEH WEN-LUNG; ANTCZAK CASIMIR; MCGOLRICK JEFFRY DAVID; ROTH MICHAEL JOSEPH; WRONA MARK
    权利人:MAXIM PHARMACEUTICALS
    摘要:The invention disclosed herein relates to the preparation of pharmaceutical grades of histamine dihydrochloride using a two step non-enzymatic synthetic method. The invention disclosed herein describes the synthesis of histamine dihydrochloride by the non-enzymatic decarboxylation of histidine and the step-wise conversion of the decarboxylated product to the dihydrochloride salt form. The invention disclosed herein considers a final product of histamine dihydrochloride containing less than each of the following: 0.8% L -histidine HCl monohydrate, 0.1% individual chromatographic impurities, and 2% total impurities, to be acceptable for pharmaceutical use.

    专利号:US-2002035268-A1
    优先权日:1998-12-23
    标题 :Synthesis of histamine dihydrochloride

    专利号:US-2003138964-A1
    优先权日:1998-12-23
    标题 :Synthesis of histamine dihydrochloride

    专利号:US-2012172326-A1
    优先权日:2008-11-28
    标题 :Moisturizing Mixture, Cosmetic And/Or Pharmaceutical Compositions Containing The Moisturizing Mixture, Use Of The Moisturizing Mixture, And Cosmetic Method
    发明人:DA LUZ MOREIRA PATRICIA; SIQUEIRA JORGE ADRIANO TADEU; PALMEIRA PORTUGAL MARQUES JULIANA; GESZTESI JEAN LUC; LEITE RIBEIRO PHILIP; ROCHA SARA
    权利人:DA LUZ MOREIRA PATRICIA; SIQUEIRA JORGE ADRIANO TADEU; PALMEIRA PORTUGAL MARQUES JULIANA; GESZTESI JEAN LUC; LEITE RIBEIRO PHILIP; ROCHA SARA; NATURA COSMETICOS SA
    摘要:The present invention refers to a moisturizing mixture for sensitive skins, atopic dermatitis and/or Ichthyosis vulgaris containing a synergistic combination among its constituents, and cosmetic and/ pharmaceutical compositions containing said moisturizing mixture. The invention also refers to a moisturizing mixture comprising a synergistic combination between at least one cutaneous-barrier repairing agent; NMF-precursor amino acids; and at least one filagrin-synthesis stimulating agent. Cosmetic and/or pharmaceutical compositions comprising said moisturizing mixture and a physiologically acceptable carrier are also described in the present invention.

    专利号:ZA-200104552-B
    优先权日:1998-12-23
    标 题:Synthesis of histamine dihydrochloride.

    专利号:JP-2002533445-A
    优先权日:1998-12-23
    标题:Synthesis of histamine dihydrochloride

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献

    合成方法参考DOI号:10.1021/jo00154a019
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知