CAS: 55341-87-2; 3-Amino-2-Thiophenecarboxylic Acid

该化合物是一种异环化合物,其特点是氨基氨基和硫苯环上的箱状酸功能组.这一结构使它成为有机合成的多功能中间体,特别是在制药,农用化学品和功能材料的制作方面.它的反应场地允许选择性的修改,从而能够形成氨化物,酯或其他衍生物.该化合物的稳定性和与各种反应条件的兼容性增强了其在药用化学中的效用,它作为生物活性分子的构件.其定义清晰的纯度和一贯性能使它成为研究和工业应用的可靠选择.

结构式图片

上下游产品

CAS号22288-78-4 3-氨基-2-噻吩甲酸甲酯 | CAS号501-53-1 氯甲酸苄酯 | CAS号50901-18-3 3-(乙酰胺基)噻吩-2-羧酸 | CAS号17721-06-1 3-氨基噻吩 | CAS号22288-78-4 3-氨基-2-噻吩甲酸甲酯 | CAS号65076-02-0 2-((噻吩-3-基氨基)亚甲...

合成工艺路线路线简述

    📜3-氨基-2-噻吩甲酸甲酯置于sodium Hydroxide体系中,化学反应生成 3-氨基-2-噻吩甲酸
    参考文献:噻吩并嘧啶和噻吩并吡啶的vegfr-2激酶活性抑制剂的设计和sar.
    标题:噻吩并嘧啶和噻吩并吡啶的vegfr-2激酶活性抑制剂的设计和sar.
    摘要:已经鉴定出新型的噻吩并嘧啶和噻吩并吡啶类是vegfr-2激酶的有效抑制剂.介绍了这些化合物的合成和sar,以及成功减少铅系列中egfr活性的努力.
    DOI:10.1016/j.Bmcl.2003.10.030

    海关参考信息

    专利信息


    专利号:FR-2844797-A1
    优先权日:2002-09-24
    标 题:NEW PROCESS FOR THE INDUSTRIAL SYNTHESIS OF ACID TETRAESTERS 5- [BIS (CARBOXYMETHYL)] - 3-CARBOXYMETHYL-4-CYANO-2- THIOPHENECARBOXYLIC AND APPLICATION TO THE SYNTHESIS OF BIVALENT HYDERS OF RANELATES ACID

    专利号:JP-2008524251-A
    优先权日:2004-12-20
    标 题 :Process for the synthesis of azetidinone

    专利号:JP-4890466-B2
    优先权日:2004-12-20
    标 题 :Process for the synthesis of azetidinone

    专利号:US-2008261823-A1
    优先权日:2004-12-10
    标 题 :Fluorescent Nucleoside Analogs That Mimic Naturally Occurring Nucleosides
    发明人:TOR YITZHAK
    权利人:TOR YITZHAK
    摘要:The present invention provides fluorescent nucleoside analogs with conjugated membered heterocycles, including furan and thiophene. The fluorescent nucleoside analogs maintain structural similarity to naturally occurring nucleoside bases, mimicking shape, size, hybridization, and recognition properties. Incorporation of the fluorescent cyclic compounds confers specific photophysical characteristics including a bathochromic (red) shift of the absorption spectrum to minimize absorption overlap with naturally occurring nucleoside bases, and a shift to the long emission wavelength in the visible range. The invention also provides for various methods of synthesizing the fluorescent nucleoside analogs and incorporating the fluorescent analogs in DNA, RNA, or oligomer synthesis. Further, methods of detecting the fluorescent nucleoside analogs in an oligonucleotide or oligomer are provided. The subject compounds are useful as probes in the study of the structure and dynamics of nucleic acids and their complexes with proteins.

    专利号:CN-105111197-B
    优先权日:2015-08-26
    标 题:Synthesis method of raltitrexed

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1038/s41570-024-00656-5
    摘要:Katoh T, Suga H. Reprogramming the genetic code with flexizymes. Nat Rev Chem. 2024 Dec;8(12):879–92. doi: 10.1038/s41570-024-00656-5.
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