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CAS号22288-78-4 3-氨基-2-噻吩甲酸甲酯 | CAS号501-53-1 氯甲酸苄酯 | CAS号50901-18-3 3-(乙酰胺基)噻吩-2-羧酸 | CAS号17721-06-1 3-氨基噻吩 | CAS号22288-78-4 3-氨基-2-噻吩甲酸甲酯 | CAS号65076-02-0 2-((噻吩-3-基氨基)亚甲...📜3-氨基-2-噻吩甲酸甲酯置于sodium Hydroxide体系中,化学反应生成 3-氨基-2-噻吩甲酸
参考文献:噻吩并嘧啶和噻吩并吡啶的vegfr-2激酶活性抑制剂的设计和sar.
标题:噻吩并嘧啶和噻吩并吡啶的vegfr-2激酶活性抑制剂的设计和sar.
摘要:已经鉴定出新型的噻吩并嘧啶和噻吩并吡啶类是vegfr-2激酶的有效抑制剂.介绍了这些化合物的合成和sar,以及成功减少铅系列中egfr活性的努力.
DOI:10.1016/j.Bmcl.2003.10.030
专利信息
专利号:FR-2844797-A1
优先权日:2002-09-24
标 题:NEW PROCESS FOR THE INDUSTRIAL SYNTHESIS OF ACID TETRAESTERS 5- [BIS (CARBOXYMETHYL)] - 3-CARBOXYMETHYL-4-CYANO-2- THIOPHENECARBOXYLIC AND APPLICATION TO THE SYNTHESIS OF BIVALENT HYDERS OF RANELATES ACID
专利号:JP-2008524251-A
优先权日:2004-12-20
标 题 :Process for the synthesis of azetidinone
专利号:JP-4890466-B2
优先权日:2004-12-20
标 题 :Process for the synthesis of azetidinone
专利号:US-2008261823-A1
优先权日:2004-12-10
标 题 :Fluorescent Nucleoside Analogs That Mimic Naturally Occurring Nucleosides
发明人:TOR YITZHAK
权利人:TOR YITZHAK
摘要:The present invention provides fluorescent nucleoside analogs with conjugated membered heterocycles, including furan and thiophene. The fluorescent nucleoside analogs maintain structural similarity to naturally occurring nucleoside bases, mimicking shape, size, hybridization, and recognition properties. Incorporation of the fluorescent cyclic compounds confers specific photophysical characteristics including a bathochromic (red) shift of the absorption spectrum to minimize absorption overlap with naturally occurring nucleoside bases, and a shift to the long emission wavelength in the visible range. The invention also provides for various methods of synthesizing the fluorescent nucleoside analogs and incorporating the fluorescent analogs in DNA, RNA, or oligomer synthesis. Further, methods of detecting the fluorescent nucleoside analogs in an oligonucleotide or oligomer are provided. The subject compounds are useful as probes in the study of the structure and dynamics of nucleic acids and their complexes with proteins.
专利号:CN-105111197-B
优先权日:2015-08-26
标 题:Synthesis method of raltitrexed