CAS: 5518-62-7; 2-Phosphanylethylphosphane

上下游产品

tetraethyl ethylenebis(phosphonate) 1,2-bis(dichlorophosphino)ethane 1,2-bis((2S,5S)-2,5-dimethylphospholano)ethane (S)-Et-BPE 1,2-bis((2R,5R)-2,5-diisopropylphospholano)ethane (+)-1,2-bis((2R,5R)-2,5-diethylphospholano)ethane

📜亚乙基二磷酸四乙酯置于lithium Aluminium Tetrahydride体系中,用 乙醚 作为反应溶剂,化学反应 0.5H,反应生成 1,2-双(膦酰)乙烷
参考文献:具有三(羟甲基)膦配体的水溶性铜(i)配合物的体外抗肿瘤活性.
标题:具有三(羟甲基)膦配体的水溶性铜(i)配合物的体外抗肿瘤活性.
摘要:单阳离子亲水性配合物[cu(thp)4](+)3和[cu(bhpe)2](+)4是通过存在下不稳定的[cu(ch3Cn)4] [pf6]前体通过配体交换反应合成的过量的相关亲水性膦.针对一组几种人类肿瘤细胞系测试了复合物3和4.已经显示出复合物3的细胞毒性比顺铂高约1个数量级.对顺铂和多药耐药表型进行的化学敏感性测试表明,复合物3通过与参考药物不同的作用机理起作用.不同的短期增殖试验表明,溶酶体损伤是与复杂3细胞毒性相关的早期细胞事件,可能是由活性氧的产生增加所介导的.
DOI:10.1021/jm701146C

专利信息

专利号:US-2025197431-A1
优先权日:2023-12-15
标 题:Methods and systems for forming a layer comprising silicon and composition and synthesis of silicon precursor
发明人：ROMERO PATRICIO EDUARDO; VERVUURT RENÉ HENRICUS JOZEF; DEZELAH CHARLES; PORE VILJAMI J
权利人:ASM IP HOLDING BV
摘要:Disclosed are methods and systems for forming a silicon-containing layer on a substrate. Further disclosed are composition and synthesis of silicon-containing precursor. The methods for forming a silicon-containing layer comprise executing a plurality of deposition cycles. A deposition cycle comprises a first precursor pulse that comprises exposing the substrate to a first precursor. The first precursor comprises a molecule comprising a P—Si bond. A deposition cycle further comprises a plasma pulse that comprises exposing the substrate to a plasma treatment. The plasma treatment comprises generating a plasma.

专利号:US-7390931-B2
优先权日:2004-04-01
标 题:Preparation of P-chirogenic phospholanes and their use in asymmetric synthesis
发明人：HOGE II GARRETT STEWART
权利人:PFIZER
摘要:Materials and methods for preparing P-chirogenic monophospholanes and bisphospholanes are disclosed. The methods employ stereoselective cyclization to generate the phospholane rings followed by pyramidal inversion to access a variety of P-chirogenic phospholanes. When bound to transition metals such as rhodium, the disclosed P-chirogenic phospholanes may be used as catalysts in asymmetric synthesis of valuable pharmaceutical chemical entities, including pregabalin.

专利号:US-6043396-A
优先权日:1997-06-18
标题:Preparation of optically active phospholanes, their metal complexes and use in asymmetric synthesis
发明人：STUERMER RAINER; BOERNER ARMIN; HOLZ JENS; VOSS GUDRUN
权利人:BASF AG
摘要:Phospholanes and diphospholanes of the formula I ##STR1## where: R 1 and R 2 are, independently of one another, C 1 -C 6 -alkyl, aryl, alkylaryl, n R 1 is also hydrogen, n A is either R 1 or ##STR2## B is a linker having 1-5 carbon atoms between the two phosphorus atoms, and their use as catalyst in asymmetric synthesis.

专利号:US-8546570-B2
优先权日:2008-07-04
标题 :Process for preparing cationic rhodium complexes
发明人：NEDDEN HANS GUENTER
权利人:NEDDEN HANS GUENTER; JOHNSON MATTHEY PLC
摘要:A process is described for the synthesis of a cationic [rhodium diolefin phosphorus ligand] complex comprising the steps of: (a) reacting a rhodium-diolefin-1,3-diketonate and an acid in a ketone solvent, (b) adding a stabilising olefin to form a stabilised cationic rhodium compound, and (c) mixing a phosphorus ligand with the solution of the stabilised cationic rhodium compound to form a solution of the cationic [rhodium diolefin phosphorus ligand] complex. The solution may be used directly or the complex recovered. In one embodiment, the solution may be combined with a co-solvent and the ketone removed to give a new catalyst solution, from which the complex may be recovered.

专利号:US-7355073-B2
优先权日:2001-07-23
标题 :Synthesis of diazaphosphacycles

专利号:WO-2025129004-A1
优先权日:2023-12-15
标题:Methods and systems for forming a layer comprising silicon and composition and synthesis of silicon precursor