CAS: 374-01-6; 1,1,1-Trifluoro-2-Propanol

相似化合物

3539-97-7 17628-73-8 920-66-1

上下游产品

CAS号677-21-4 3,3,3-三氟丙烯 | CAS号359-41-1 1,1,1-三氟-2,3-环氧丙烷 | CAS号421-50-1 1,1,1-三氟丙酮(TFK) | CAS号274-07-7 儿茶酚硼烷 | CAS号25015-63-8 频那醇硼烷 | CAS号344324-54-5 trifluoroisopro... | CAS号917-64-6 甲基碘化镁 | CAS号431-47-0 三氟乙酸甲酯(TFAM) | CAS号383-63-1 三氟乙酸乙酯 | CAS号75-90-1 三氟乙醛 | CAS号400-37-3 1,1,1-三氟-2-乙酸丙酯 | CAS号421-46-5 2-溴-1,1,1-三氟丙烷 | CAS号421-50-1 1,1,1-三氟丙酮(TFK) | CAS号845616-82-2 (S)-2-(1-Methyl...

1,1,1-三氟丙酮置于sodium Formate Alcohol Dehydrogenase From Rhodococcus Species,Formate Dehydrogenase (Cytochrome),Nicotinamide Adenine Dinucleotide体系中,化学反应生成1,1,1-三氟异丙醇
参考文献:全氟手性醇的生物还原合成
标题:全氟手性醇的生物还原合成
摘要:全氟手性醇是用于药物和农用化学品的有趣的构建基块.通过不对称还原相应的酮,可以生产出不同的手性(R)和(S)构型的全氟化醇.与不同的辅因子再生系统结合使用市售的醇脱氢酶作为催化剂.在大多数情况下,观测到的选择性高于99%.结果还证明了cf 3基团对醇脱氢酶的反应性和对映选择性的影响.
Doi:10.1016/j.Tetlet.2006.05.061

专利信息

专利号:US-2013338369-A1
优先权日:2011-03-07
标 题 :Process for the Synthesis of Aminobiphenylene
发明人：HEINRICH MARKUS; PRATSCH GERALD
权利人:HEINRICH MARKUS; PRATSCH GERALD; BASF SE
摘要:The present invention relates to a process for the synthesis of 2-aminobiphenylene and derivatives thereof by reacting a benzene diazonium salt with an aniline compound under basic reaction conditions.

专利号:US-10570114-B2
优先权日:2016-05-19
标题:Synthesis of 6-aryl-4-aminopicolinates and 2-aryl-6-aminopyrimidine-4-carboxylates by direct suzuki coupling
发明人：FISK JASON S; LI XIAOYONG; Muehlfeld Mark; BAUMAN ROBERT S; OPPENHEIMER JOSSIAN; TU SIYU; NITZ MARK A; CHAKRABARTI REETAM; FEIST SHAWN D; RINGER JAMES W; LENG RONALD B
权利人:DOW AGROSCIENCES LLC
摘要:Improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates and arylalkyl and alkyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates, are described herein. The improved methods include a direct Suzuki coupling step, which eliminates the protection/de-protection steps in the current chemical process, and therefore eliminates or reduces various raw materials, equipment and cycle time as well as modification of other process conditions including use of crude AP, use of ABA-diMe, and varying pH, catalyst concentration, solvent composition, and/or workup procedures. This includes synthesis of 2-aryl-6-aminopyrimidine-4-carboxylates.

专利号:US-2008280855-A1
优先权日:2005-06-22
标 题 :Process For the Production of Intermediates For the Preparation of Tricyclic Benzimidazoles
发明人：CHIESA MARIA VITTORIA; PALMER ANDREAS; BUHR WILM; ZIMMERMANN PETER JAN; BREHM CHRISTOF; SIMON WOLFGANG-ALEXANDER; POSTIUS STEFAN; KROMER WOLFGANG; ZANOTTI-GEROSA ANTONIO
权利人:NYCOMED GMBH
摘要:The invention relates to a process for the synthesis of compounds of the formula 1-a and compounds of the formula 1-b. n n n n n n n n n n The compounds of the formula 1-a and the compounds of the formula 1-b, in which the substituents R1, R2, R3, and Ar have the meanings indicated in the description, are valuable intermediates for the preparation of pharmaceutically active compounds.

专利号:US-2023174490-A1
优先权日:2020-03-18
标 题 :Improved synthesis of 6-aryl-4-aminopicolinates
发明人：ZHANG CHUNMING; TU SIYU; LENG RONALD B; IRVINE NICHOLAS; SCHUITMAN ABRAHAM; SHINKLE AARON; DEVARAJ JAYACHANDRAN; ZU CHENGLI
权利人:CORTEVA AGRISCIENCE LLC
摘要:The present disclosure relates to improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates.

专利号:US-7812161-B2
优先权日:2007-03-05
标 题 :Synthesis of GlyT-1 inhibitors
发明人：PFLEGER CHRISTOPHE; WALDMEIER PIUS; WANG SHAONING
权利人:HOFFMANN LA ROCHE
摘要:The present invention relates to a process for preparation of a compound of formula I n nwhereinn Het, R 1 , R 2 , R 3 , and n are as defined herein and pharmaceutically acceptable acid addition salts thereof, which comprises reacting a compound of formula 21 with a compound of formula 8 to obtain a compound of formula 11 and coupling the compound of formula 11 in the presence of a coupling reagent or the corresponding acid halogenide with a compound of formula 15 to obtain a compound of formula I.

专利号:US-3992456-A
优先权日:1969-04-16
标题:Synthesis of alkadienols
发明人：ATKINS KENNETH EARL; MANYIK ROBERT MICHAEL; O'CONNOR GEORGE LAWRENCE
权利人:UNION CARBIDE CORP
摘要:Alkadienols are prepared by reacting a conjugated diolefin, such as butadiene, with water in the presence of palladium or platinum catalyst and in the presence of solvents. The addition of carbon dioxide to the reaction mixture greatly increases the yield of alkadienols. The products can be hydrogenated to saturated alcohols, useful for making plasticizers.