CAS: 3012-65-5; Diammonium Citrate

柠檬酸 反应生成柠檬酸氢二铵
参考文献:Rosca,Dumitru;Ambrono,Daniela;Indrei,Livius
标题:Rosca,Dumitru;Ambrono,Daniela;Indrei,Livius

专利信息

专利号:WO-2024084510-A1
优先权日:2022-10-20
标题 :Glutamic acid independent process for synthesis of poly gamma glutamic acid
发明人：DHARNE MAHESH SHANTAPPA; NAIR PRANAV GIRIJAVALLABHAN
权利人:COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN OF S
摘要:The present invention relates to a cost-effective process for the synthesis of hyper-production of poly gamma glutamic acid using L-glutamic acid independent approach. Specifically, the present invention relates to the synthesis of poly gamma glutamic acid (γ-PGA) from jaggery, blackstrap molasses, and floral waste. More particularly, the present invention relates to a process for the synthesis of poly gamma glutamic acid in high yield and in the presence of Bacillus paralicheniformis NCIM 5769.

专利号:US-8193384-B2
优先权日:2005-07-29
标 题 :Polymer-bound phosphitylating reagents for the synthesis of organophosphorus compounds
发明人：PARANG KEYKAVOUS; AHAMDIBENI YOUSEF
权利人:PARANG KEYKAVOUS; AHAMDIBENI YOUSEF; RHODE ISLAND EDUCATION
摘要:The synthesis and biochemical utility of modified oligonucleotides containing diphosphodiester internucleotide linkages. The synthesis of these compounds was carried out using diphosphitylating reagents. Oligonucleotides containing diphosphate diester bridges wherein said oligonucleotides are synthesized via a solid-phase synthesis strategy to form modified oligonucleotides. Diphosphitylating, triphosphitylating, tetraphosphitylating, β-triphosphitylating, bifunctional diphosphitylating, bifunctional triphosphitylating, and bifunctional tetraphosphitylating reagents wherein, the phosphorus atoms are linked together through oxygen, sulfur, amino, or methylene groups and/or are substituted with chlorine, diisopropylamine and cyanoethoxy groups.

专利号:US-12383499-B2
优先权日:2018-01-01
标题:Scale up synthesis of silicasome nanocarriers
发明人：NEL ANDRE E; MENG HUAN; LIU XIANGSHENG
权利人:UNIV CALIFORNIA
摘要:In order to facilitate the approval and commercialization of silicasome drug delivery systems (e.g. irinotecan silicasomes) it is necessary to scale up synthesis of the drug-loaded silicasomes. In this regard, it was discovered that the synthesis protocols used for laboratory synthesis of drug-loaded silicasomes (e.g., 500 mg/batch) do not scale to large scale silicasome production, because the resulting products were too heterogeneous for use as pharmaceuticals. Accordingly, new methods are provided herein that effectively afford the large-scale production of mesoporous silica nanoparticles (MSNPs) and lipid bilayer coated MSNPs (silicasomes).

专利号:US-9409153-B2
优先权日:2007-12-28
标题:Supported Mo—O—K—MexOy catalyst for the synthesis of methanethiol from high H2S-containing syngas
发明人：YANG YIQUAN; HAO YINGJUAN; CHEN AIPING; WANG QI; YANG LINGMEI; LI QIAOLING; DAI SHENJUN; FANG WEIPING; BARTH JAN-OLAF; WECKBECKER CHRISTOPH; HUTHMACHER KLAUS
权利人:YANG YIQUAN; HAO YINGJUAN; CHEN AIPING; WANG QI; YANG LINGMEI; LI QIAOLING; DAI SHENJUN; FANG WEIPING; BARTH JAN-OLAF; WECKBECKER CHRISTOPH; HUTHMACHER KLAUS; EVONIK DEGUSSA GMBH
摘要:This invention is related to a preparation method of a supported catalyst Mo—O—K-Me x O y for the synthesis of methanethiol from H 2 S-containing syngas. The catalyst comprises of an active component of Mo—O—K-based species, an active promoter and a support denoted as metal (or metals)-carrier. The support is prepared by electroless plating method in such a way that the metal or metals chosen are plated onto the surface of the carrier. Transition metal, especially Fe, Co or Ni are selected to be the plating metal, while SiO 2 , Al 2 O 3 or TiO 2 are selected to be carrier. The catalyst thus prepared is found to be efficient for the synthesis of methanethiol from H 2 S-containing syngasor carbon oxides/hydrogen mixtures, especially regarding a minor formation of the by-product CO 2 .

专利号:US-4427587-A
优先权日:1982-11-10
标 题:Total synthesis of antitumor antibiotics BBM-2040A and BBM-2040B
发明人：KANEKO TAKUSHI; WONG HENRY S L
权利人:BRISTOL MYERS CO
摘要:A new chemical synthesis of the pyrrolobenzodiazepine antibiotics BBM-2040A and B is disclosed. The disclosed total synthesis uses readily available starting materials and provides a useful alternative to the microbiological procedure previously used to prepare these antibiotics.

专利号:WO-2024036115-A1
优先权日:2022-08-08
标题:Continuous flow synthesis of lorazepam
发明人：THOMPSON DAVID; BIYANI SHRUTI; HYUN SEOK-HEE; MCGUIRE MICHAEL
权利人:PURDUE RESEARCH FOUNDATION; CONTINUITY PHARMA LLC
摘要:A method for synthesis of Lorazepam in a continuous flow using continuous flow reactor, in which method comprises five steps including N-acylation, diazepine ring closure, imine N- oxidation, Polonovski-type rearrangement, and ester hydrolysis; a green reagent comprising a peroxide reagent and rhenium oxide catalyst for N-oxidation of delorazepam; and an ammonium source combination for the synthesis of delorazepam.