CAS: 18259-05-7; 2,3,4,5,6-Pentachlorobiphenyl
该化合物是一种属于多氯联苯类别的氯化联苯化合物,其特点是,联苯结构中存在5个与联苯结构相连的氯原子,该结构由一个单一的联结连接,由两个苯环组成,氯化模式对其化学特性,包括其疏水性,热稳定性和抗降解性产生重大影响. 2,3,4,5,6-Penta-氯联苯在室内温度上一般是固体,具有低挥发性,其环境持久性和生物累积潜力,引起人们对其毒性和生态影响的关切.多氯联苯,包括这种化合物在内,对人类和野生生物的健康造成各种不利影响,导致对其使用和处置的管制限制.通常使用气相色谱质谱仪等分析方法,在环境样品中检测和量化这种化合物.
- 英文名称2,3,4,5,6-Pentachlorobiphenyl
- 中文名称1,2,3,4,5-五氯联苯
- IUPAC名称1,2,3,4,5-pentachloro-6-phenylbenzene
- 其它别名Biphenyl,2,3,4,5,6-pentachloro- (8CI); 2,3,4,5,6-Pentachloro-1,1'-biphenyl; 2,3,4,5,6-Pentachlorobiphenyl
- CAS编号18259-05-7
- MFCD编号:MFCD00152724
- FDA UNII编号:112AB9M1UF
- 分子式:C12H5Cl5分子量:326.43
- 产品CID: 940800
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: GGMPTLAAIUQMIE-UHFFFAOYSA-N
- 1S/C12H5Cl5/c13-8-7(6-4-2-1-3-5-6)9(14)11(16)12(17)10(8)15/h1-5H
- 计算化学: 氢键受体数*氢键供体数0.0可旋转键数1.0
物理性质
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
hexachlorobenzene phenylboronic acid bromobenzene PCB 61 2,3,5,6-tetrachlorobiphenyl 2,3,4,6-Tetrachlorobiphenyl 1,2,3,4-tetrachlorodibenzofuran合成工艺路线路线简述
📜五氯碘苯 以95%的收率获得
参考文献:Bratt J.; Iddon B.; Mack A. G.; Suschitzky H.; Taylor J. A.; Wakefield B.+,J. Chem. Soc. Perkin Trans.,Part 1,1980,No 2,648-656
标题:Bratt J.; Iddon B.; Mack A. G.; Suschitzky H.; Taylor J. A.; Wakefield B.+,J. Chem. Soc. Perkin Trans.,Part 1,1980,No 2,648-656
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:RU-2168521-C2
优先权日:1999-08-10
标题 :Method of synthesis of polyfluorinated esters based on poly- -chlorodiphenyls used as intermediate compounds for production of lubricant oils, antiadhesion and antifriction compositions
专利号:US-8952207-B2
优先权日:2007-09-11
标题:Copper-catalyzed C—H bond arylation
发明人：DAUGULIS OLAFS; DO HIEN-QUANG
权利人:DAUGULIS OLAFS; DO HIEN-QUANG; UNIV HOUSTON SYSTEM
摘要:The present invention is a one-step method for efficiently converting carbon-hydrogen bonds into carbon-carbon bonds using a combination of aryl halides, a substrate, and a copper salt as catalyst. This method allows faster introduction of complex molecular entities, a process that would otherwise require many more steps. This invention is particularly relevant for the organic synthesis of complex molecules such as, but not limited to, pharmacophores and explosives.
专利号:CN-102249840-A
优先权日:2011-04-20
标 题 :Catalytic Synthesis of Biphenyl from Waste Capacitor Oil in Subcritical Water
专利号:CN-102249840-B
优先权日:2011-04-20
标 题 :Catalytic Synthesis of Biphenyl from Waste Capacitor Oil in Subcritical Water
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:Gigiena i Sanitariya. For English translation, see HYSAAV., 53(5)(6), 1988
参考文献:10.1007/s11030-005-9009-x
摘要:Roy DR, Sarkar U, Chattaraj PK, Mitra A, Padmanabhan J, Parthasarathi R, Subramanian V, Van Damme S, Bultinck P. Analyzing toxicity through electrophilicity. Mol Divers. 2006 May;10(2):119–31. doi: 10.1007/s11030-005-9009-x.
参考文献:10.1007/s00244-004-0251-5
摘要:Minh TB, Watanabe M, Kajiwara N, Iwata H, Takahashi S, Subramanian A, Tanabe S, Watanabe S, Yamada T, Hata J. Human Blood Monitoring Program in Japan: Contamination and Bioaccumulation of Persistent Organochlorines in Japanese Residents. Archives of Environmental Contamination and Toxicology. 2006 May 22;51(2):296–313. doi: 10.1007/s00244-004-0251-5.
参考文献:10.1007/s00244-011-9679-6
摘要:Moon H, Lee D, Lee YS, Choi M, Choi H, Kannan K. Polybrominated Diphenyl Ethers, Polychlorinated Biphenyls, and Organochlorine Pesticides in Adipose Tissues of Korean Women. Archives of Environmental Contamination and Toxicology. 2011 May 19;62(1):176–84. doi: 10.1007/s00244-011-9679-6.
参考文献:10.1007/bf00199075
摘要:Rastogi SC. Investigation of isomer specific polychlorinated biphenyls in printing inks. Bulletin of Environmental Contamination and Toxicology. 1992 Apr;48(4):567–71. doi: 10.1007/bf00199075.
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