CAS: 13194-48-4; Ethoprophos

丙烷-1-硫醇,二氯磷酸乙酯 以91%的收率获得
参考文献:Brochard,Jean-Michel;Frisou,Francois;Roy,Pierre Le
标题:Brochard,Jean-Michel;Frisou,Francois;Roy,Pierre Le

专利信息

专利号:WO-2017051326-A1
优先权日:2015-09-23
标 题 :New processes and intermediates useful in synthesis of nep inhibitors
发明人：MARTIN BENJAMIN; PENN GERHARD; SCHENKEL BERTHOLD; BOURNE SAMUEL; LAU SHING-HING; LEY Steven
权利人:NOVARTIS AG; MARTIN BENJAMIN; PENN GERHARD; SCHENKEL BERTHOLD; BOURNE SAMUEL; LAU SHING-HING; LEY Steven
摘要:The invention relates to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, in particular neutral endopeptidase (NEP) inhibitors such as sacubitril, and prodrugs thereof.

专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人：BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

专利号:US-5157149-A
优先权日:1991-06-04
标 题 :Enantioselective synthesis of L-(-)-4- boronophenylalanine (L-BPA)
发明人：SAMSEL EDWARD G
权利人:US ENERGY
摘要:A method of making substantially pure L-BPA is disclosed. The method includes the steps of reacting 4-bromobenzaldehyde with ethylene glycol to form 4-bromobenzaldehyde ethylene glycol acetal, sequentially reacting 4-bromobenzaldehyde ethyleneglycol acetal with Mg to produce the Grignard reagent and thereafter reacting with tributyl borate and then converting to an acid environment to form 4-boronobenzaldehyde, reacting 4-boronobenzaldehyde with diethanol amine to form 4-boronobenzaldehyde diethanolamine ester, condensing the 4-boronobenzaldehyde diethanolamine ester with 2-phenyl-2-oxazolin-5-one to form an azlactone, reacting the azlactone with an alkali metal hydroxide to form z-α-benzoylamino-4-boronocinnamic acid, asymmetrically hydrogenating the z-α-benzoylamino-4-boronocinnamic acid in the presence of a catalyst of a cheltate complex of rhodium (I) with chiral bisphosphines to form L-(+)-N-benzoyl-4-boronophenylalanine, and thereafter acidifying the L-(+)-N-benzoyl-4-boronophenylalanine in an organic medium to produce L-BPA.

专利号:US-7495123-B2
优先权日:2004-04-05
标 题:Process for the preparation of enantiomerically enriched beta amino acid derivatives
发明人：XIAO YI; SUN YONGKUI; ROSNER THORSTEN; RIVERA NELO R; KRSKA SHANE W; CLAUSEN ANDREW M; ARMSTRONG III JOSEPH D; SPINDLER FELIX; MALAN CHRISTOPHE
权利人:SOLVIAS AG; MERCK & CO INC
摘要:The present invention relates to a process for the efficient preparation of enantiomerically enriched beta amino acid derivatives wherein the amino group is unprotected. The product chiral beta amino acid derivatives are useful in the asymmetric synthesis of biologically active molecules. The process comprises an enantioselective hydrogenation of an amine-unprotected prochiral beta-amino acrylic acid or derivative thereof in the presence of a rhodium metal precursor complexed with a chiral mono- or bisphosphine ligand.

专利号:US-10906880-B2
优先权日:2016-01-26
标题:Kind of isothiazole oxime ether-containing strobilurin derivatives and its preparation methods and application
发明人：FAN ZHIJIN; CHEN LAI; GUO XIAOFENG; ZHU YUJIE; QIAN XIAOLIN; MA LIUYONG; ZHANG NAILOU; WANG HAIXIA; ZHANG ZHIMING; XU JINGHUA; SONG YINQI
权利人:UNIV NANKAI
摘要:The present invention is that provided a synthesis method of a series of isothiazole oxime ether containing strobilurin derivatives IV. The present invention relates to 3,4-dichloroisothiazolyl oxime ether strobilurin derivatives, and their chemical structural formula is as shown by IV. n n n n n n n n n n The invention discloses the structural formula of the above compound, the synthesis method and the use as an insecticide, a fungicide, an anti-plant virus agent, and an agriculturally acceptable auxiliary or synergist and a commercial insecticide. The use of a fungicide, an anti-plant virus agent and an acaricide in combination for controlling agricultural, forestry, horticultural plant pests, diseases, virus diseases and preparation methods.

专利号:US-11823345-B2
优先权日:2020-05-12
标题 :Example-based real-time clothing synthesis method
发明人：WU NANNAN; JIN XIAOGANG
权利人:UNIV ZHEJIANG
摘要:The invention presents an example-based real-time clothing synthesis method, which includes the following steps: creating the 3D human model according to the input body pose parameters and the body shape parameters; generating 3D clothing deformation on the standard shape and the input pose through a clothing pose model; searching nearby clothing shape models according to the body pose parameters; for each nearby clothing shape model, generating corresponding 3D clothing mesh based on the body shape parameters, and then deforming the clothing mesh toward the input pose using Linear Blend Skinning (LBS) method; synthesizing the clothing deformation for the input body pose and shape using the clothing data obtained in above steps; resolving the interpenetrations between the clothing data and the human model. The invention can generate real-time clothing animation results with detailed wrinkles for various body poses and shapes with different clothing types on a commodity CPU, without resizing the cloth model. It has potential use in assessment of fitness in virtual try-on, as well as in the field of computer animation and video games.