CAS: 7787-52-2; Beryllium Hydride

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    专利信息


    专利号:US-6540970-B1
    优先权日:1999-11-18
    标题:Method for the synthesis of molecular sieves
    发明人:STROHMAIER KARL G; VAUGHAN DAVID E W
    权利人:EXXON MOBIL CHEM PATENTS INC
    摘要:The present invention provides a method for the synthesis of MeAPO molecular sieves which includes the following steps: providing a source of alumina, a source of phosphorus, water, and a template suitable for forming a MeAPO molecular sieve; providing a source of metal (Me) including metal particles, the metal particles measuring, in their largest dimension, equal to or less than five nanometers; providing a water soluble organic solvent capable of solubilizing the source of metal; forming a synthesis mixture from the source of alumina, the source of phosphorus, the water, the template, the source of metal, and the solvent; and forming a MeAPO molecular sieve from the synthesis mixture.

    专利号:US-7888337-B2
    优先权日:2007-08-31
    标 题 :Synthesis of oseltamivir containing phosphonate congeners with anti-influenza activity
    发明人:WONG CHI-HUEY; FANG JIM-MIN; SHIE JIUN-JIE; CHENG YIH-SHYUN EDMOND; JAN JIA-TSRONG
    权利人:ACADEMIA SINICA
    摘要:Novel phosphonate compounds are described. The compounds have activity as neuraminidase inhibitors against wild-type and H274Y mutant of H1N1 and H5N1 viruses. The present disclosure also provides an enantioselective synthetic route to known neuraminidase inhibitors oseltamivir and the anti-flu drug Tamiflu®, as well as novel phosphonate compounds, via D-xylose. Another efficient and flexible synthesis of Tamiflu and the highly potent neuraminidase inhibitor Tamiphosphor was also achieved in 11 steps and >20% overall yields from the readily available fermentation product (1S-cis)-3-bromo-3,5 -cyclohexadiene-1,2-diol. Most of the reaction intermediates were obtained as crystals without tedious purification procedures. The key transformations include an initial regio- and stereoselective bromoamidation of a bromoarene cis-dihydrodiol, as well as the final palladium-catalyzed carbonylation and phosphonylation.

    专利号:US-7728135-B2
    优先权日:2005-01-06
    标 题:Synthesis of CCR5 receptor antagonists
    发明人:SHI XIONGWEI; ZHU MAN; LEONG WILLIAM; DAHANUKAR VILAS; ZAVIALOV ILIA A; PROIETTI CECELIA; ZHAO SHANNON; LEE HONG-CHANG; LIU YI; NGUYEN HOA N; WU WENXUE; D SA BOSCO; LIANG FENG; TRAN LOC THANH
    权利人:SCHERING CORP
    摘要:The present invention is directed to the synthesis of 4-[4-[(R)-[1-[cyclopropylsulfonyl)-4-piperidinyl](3-fluorophenyl)methyl]-3(S)-methyl-1-piperazinyl]-1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-methylpiperidine], and intermediates therefor from readily available starting materials by a novel route.

    专利号:US-5627297-A
    优先权日:1995-04-10
    标 题 :Process for cleaving the by-products of the direct synthesis of alkylchlorosilanes
    发明人:GILBERT LAURENT; LAROZE GILLES
    权利人:RHONE POULENC CHIMIE
    摘要:The process for cleaving the heavy by-products derived from the synthesis of alkylchlorosilanes, in particular C1 to C6 alkylchlorosilanes, more particularly methylchlorosilanes, in particular for the cleavage of alkylchlorodisilanes, in particular methylchlorodisilanes having from one to five chlorine atoms, is carried out by treatment with hydrochloric acid in the presence of a catalytic system which comprises at least one metal phosphate, preferably associated with a basic impregnation compound. The metal phosphate may in particular correspond to the formula: M(XPO4)y in which M represents a metal chosen from: monovalent metals, in which case X is 2H and y=1 divalent metals, in which case X is H and y=1 trivalent metals, in which case X is absent and y=1 tetravalent metals, in which case X is: H and y=2 pentavalent metals, in which case X is 0 and y=1.

    专利号:US-6818773-B2
    优先权日:2001-10-15
    标题:Synthesis of 4-[(Z)-4-bromophenyl)(ethoxyimino) methyl]-1'-[(2,4-dimethyl-1-oxido-3-pyridinyl)carbony)]-4'-methyl-1,4-′bipiperidine
    发明人:CHEN MINZHANG; D SA BOSCO ANTHONY; LEONG WILLIAM W; GAN TONG; WONG GEORGE S K; TANG SUHAN; NIELSEN CHRISTOPHER MICHAEL
    权利人:SCHERING CORP
    摘要:In one embodiment, the present invention describes the synthesis of 4-[(Z)-(4-bromophenyl)(ethoxyimino)methyl]-1'-[(2,4-dimethyl-1-oxido-3-pyridinyl)carbonyl]-4'-methyl-1,4'-bipiperidine, and intermediates therefor from easily available starting materials by a simple route.

    专利号:US-10899616-B2
    优先权日:2019-06-20
    标 题 :Synthesis of metal oxynitrides using flame spray pyrolysis
    发明人:SASMAZ ERDEM; CORDONNIER NICOLE; MEEKINS BENJAMIN; NAGLIC JENNIFER
    权利人:UNIV SOUTH CAROLINA
    摘要:The present disclosure is directed to methods for producing metal oxynitrides using flame synthesis. Embodiments of the disclosure may provide advantages over prior synthesis techniques by reducing synthesis time. Additionally, methods and systems disclosed herein may achieve better incorporation of nitrogen atoms into the oxide structure due in part to the higher homogeneity of flame made particles and ability to control the reaction environment.

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    合成参考文献


    摘要:A91: Lindenschmidt RC, Sendelbach LE, Witschi HP, Price DJ, Fleming J, Joshi JG: Ferritin and in vivo beryllium toxicity. Toxicol Appl Pharmacol. 1986 Feb;82(2):344-50.
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