CAS: 565-75-3; 2,3,4-Trimethylpentane

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CAS号106-98-9 正丁烯 | CAS号565-77-5 2,3,4-三甲基-2-戊烯 | CAS号115-11-7 2-甲基丙烯 | CAS号107-01-7 2-丁烯 | CAS号75-28-5 异丁烷 | CAS号67-56-1 甲醇 | CAS号563-79-1 2,3-二甲基-2-丁烯 | CAS号74-88-4 碘甲烷 | CAS号54509-73-8 ethene | CAS号78-78-4 异戊烷 | CAS号565-59-3 2,3-二甲基戊烷 | CAS号464-06-2 2,2,3-三甲基丁烷 | CAS号563-80-4 甲基异丙基甲酮 | CAS号1712-64-7 硝酸异丙酯 | CAS号75-07-0 乙醛 | CAS号67-64-1 丙酮 | CAS号95-47-6 邻二甲苯 | CAS号106-42-3 对二甲苯 | CAS号66793-95-1 3-ethyl-2,2-dim... | CAS号55719-99-8 3-Methyl-2,2-di...

📜1,2,3-三甲基环戊烷置于platinum On Activated Charcoal体系中,化学反应生成 2,3,4-三甲基戊烷
参考文献:Kasanski; Koperina; Batujew,Izvestiya Akademii Nauk Sssr,Seriya Khimicheskaya,1948,P. 503,509
标题:Kasanski; Koperina; Batujew,Izvestiya Akademii Nauk Sssr,Seriya Khimicheskaya,1948,P. 503,509

专利信息

专利号:WO-9312076-A1
优先权日:1991-12-13
标题:Reagents for automated synthesis of peptide analogs
发明人：WEBB THOMAS ROY
权利人:CORVAS INT INC
摘要:Reagents suitable for synthesis of peptide analogs using automated peptide synthesis and procedures for synthesis of peptide analogs are provided.

专利号:US-2006287520-A1
优先权日:2005-05-16
标 题 :Synthesis of salinosporamide A and analogues thereof
发明人：DANISHEFSKY SAMUEL J; ENDO ATSUSHI
权利人:DANISHEFSKY SAMUEL J; ENDO ATSUSHI
摘要:A novel synthesis of salinosporamide A is provided. Salinospoamide A as well as structurally related natural products, omuralide and lactacystin, have been shown to be proteasome inhibitors. Therefore, these compounds as well as analogues of these natural products may be useful in the treatment of proliferative diseases such as cancer, autoimmune diseases, diabetic retinopathy, etc. The invention provides for the synthesis of salinosporamide A as well as analogs thereof using a convenient point for derivatization of the bicyclic core. Pharmaceutical compositions and method of using the inventive compounds are also provided.

专利号:WO-0140193-A1
优先权日:1999-12-03
标题:Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.

专利号:US-2003162992-A1
优先权日:2001-12-14
标 题 :Preparation of intermediates useful in the synthesis of antiviral nucleosides
发明人：WATANABE KYOICHI A; DU JINFA
摘要:The present invention is an efficient process for the manufacture of α-acyloxyacetaldehyde, a key intermediate in the synthesis of 1,3-oxathiolane and 1,3-dioxolane nucleosides.

专利号:US-4704450-A
优先权日:1983-02-21
标 题 :Synthesis of hpGRF(Somatocrinin) in liquid phase and intermediate peptides
发明人：DIAZ JOSEPH; DEMARNE HENRI; RONCUCCI ROMEO; SCHMELCK PAUL-HENRY
权利人:SANOFI SA
摘要:The invention relates to synthesis of hpGRF (Somatocrinin) in liquid phase and to intermediate peptides, comprising: coupling, one after the other and in the order of the sequence of the GRF, the fragments in which: (a) the side acid functions of the aspartic and glutamic acids and the side amine function of the lysine are protected by protector groups stable in the conditions of deprotection of the group Boc, (b) the guanidine function of the arginine is protected by protonation, and (c) the N-terminal amino acid is protected on the amine by the Boc group; selectively eliminating the group Boc from the N-terminal amine of the peptide in phase of elongation by hydrolysis with trifluoroacetic acid, said coupling being effected in an aprotic polar solvent and eliminating, at the end of sequence, all the protector groups by hydrolysis with the aid of a 0.1 to 1M solution of methanesulfonic or trifluoromethanesulfonic acid in trifluoroacetic acid.

专利号:US-8404804-B2
优先权日:2007-08-28
标 题 :Methods and intermediates for chemical synthesis of polypeptides and proteins
发明人：DONG ZHENG XIN; EYNON JOHN S
权利人:DONG ZHENG XIN; EYNON JOHN S; IPSEN PHARMA SAS
摘要:The present invention relates to methods and intermediates for chemical synthesis of polypeptides and proteins, and more particularly to methods and intermediates for chemically ligating a peptide fragment containing N-terminal N-methyl-cysteine (SEQ ID NO: 1) with another peptide fragment having C-terminal thioester to generate a β-(methylamino)-thioester intermediate that spontaneously rearranges to form an amide bond. Furthermore, the invention relates to methods of converting N-methyl-thiazolidine to N-methyl-cysteine (SEQ ID NO: 1) of polypeptides and proteins. The invention also relates to methods of synthesizing peptide-thioester from peptide-acid fluoride.