CAS: 34231-22-6; 3-(Aminomethyl)Benzyl Alcohol

上下游产品

1,3-dimethanol benzene methanesulfonic acid 3-hydroxymethyl-benzyl ester 3-Cyanobenzaldehyde 3-Methylbenzonitrile 3-(N,N-Dimethylaminomethyl)benzenemethanol 1,1-dimethylethyl {[3-(hydroxymethyl)phenyl]methyl}carbamate (2R)-N-[1-(3-tert-butoxycarbonylaminomethylbenzyl)piperidin-4-yl]-2-[(1R)-3,3-difluor°Cyclopentyl]-2-hydroxy-2-phenylacetamide

间甲基苯腈置于chromium(Vi) Oxide,Sodium Tetrahydroborate,水,溶剂黄146,Diborane(6)体系中,用 四氢呋喃,乙醇 用作溶剂,化学反应生成3-氨甲基苯甲醇
参考文献:Protonation Susceptibility And Fragmentation Capability Of Functional Groups In Chemical Ionization Mass Spectrometry Of Simple Bifunctional Compounds. Semi-Quantitative Interpretation Of Spectra
标题:Protonation Susceptibility And Fragmentation Capability Of Functional Groups In Chemical Ionization Mass Spectrometry Of Simple Bifunctional Compounds. Semi-Quantitative Interpretation Of Spectra
摘要:Abstractpositive‐ion,Methane‐mediated Chemical Ionization Mass Spectra Were Measured For Simple Bifunctional Aromatic Compounds Of The Type M‐xch2C6H4Ch2Y,Where X = Nh2 And N(Ch3)2,And Y = Oh And och3. Essentially Only Three Peaks Of Ions,[mh]+,[mh-Xh]+ And [mh-Yh]+,Have Appeared For Each Compound. Since The Two Functional Groups Xch2-And Ych2-Do Not Interact With Each Other After Protonation Or After Fragmentation,They Are Assumed To Be Protonated And To Undergo Fragmentations Independently. The Relative Protonation Susceptibility And Fraction Of Fragmenting [mh]+ Can Be Estimated For Each Functional Group In These Compounds. A Semi‐quantitative Interpretation Of The Observed Spectra Is Presented.
Doi:10.1002/oms.1210280203

专利信息

专利号:EP-0844261-A1
优先权日:1996-11-21
标题:Dispersions containing polyurethanes with carbonyl groups in ketone function
发明人：KOKEL NICOLAS DR; GULBINS ERICH DR; RAU MARIA GYOPAR DR; FISCHER GERHARD
权利人:BASF AG
摘要:R 1 , R 2 , R 3 jeweils Wasserstoff, C 1 - bis C 24 -Alkyl oder C 6 - bisnC 24 -Alkenyl R 4 Wasserstoff R 5 , R 6 a) gemeinsam C 4 - bis C 10 -Alkandiyl, b) jeweils C 2 - bis C 10 -Alkyl, C 5 - bis C 8 -Cycloalkylnoder C 7 - bis C 20 -Aralkyl, c) jeweils ein hydroxylterminiertes Poly-(C 2 - bisnC 4 -alkylenoxid), oder d) ein Rest R 5 oder R 6 die unter (a) bis (c) angegebenenBedeutung und der andere Rest Wasserstoffnoder ein Rest der Formel IIn nin der X C 2 - bis C 6 -Alkandiyl bedeutet und R 7 gleichbedeutend ist mit R 5 oder R 6 mit der Ausnahme,ndaß R 7 nicht ein Rest der Formel II bedeutet, nwobei n die Reste R 5 und R 6 in jedem der Fälle (a) bis (d) insgesamtneine (1) an ein aliphatisches C-Atom gebundene Hydroxylgruppenntragen, gegebenenfalls der Rest R 5 und/oder R 6 1 oder 2 aromatischngebundene Hydroxylgruppen oder 1 Nitril-, tertiäre Amino-,nCarbonsäure- oder Sulfonsäuregruppe, die gegebenenfalls innForm ihrer Salze vorliegen, trägt, und die mittlere Funktionalität (F) aller Aufbaukomponenten desnPolyurethans (A), bezogen auf die Funktionalitäten, die beimnAufbau des Polyurethans (A) in einer Additionsreaktion miteinandernreagieren, 1,5 bis 2,2 beträgt. Aqueous dispersions containing a polyurethane (A) with structural units which differ from compounds of the formula (I) in which the substituents have the following meaning: R 1 , R 2 , R 3 in each case hydrogen, C 1 - to C 24 -alkyl or C 6 - to C 24 -alkenyl R 4 hydrogen R 5 , R 6 a) together C 4 - to C 10 -alkanediyl, b) in each case C 2 to C 10 alkyl, C 5 to C 8 cycloalkyl or C 7 to C 20 aralkyl, c) in each case a hydroxyl-terminated poly (C 2 - to C 4 -alkylene oxide), or d) a radical R 5 or R 6 has the meaning given under (a) to (c) and the other radical is hydrogen or a radical of the formula II in the X C 2 - to C 6 -alkanediyl means and R 7 is equivalent to R 5 or R 6 with the exception that R 7 does not represent a radical of the formula II, in which the radicals R 5 and R 6 in each of cases (a) to (d) carry a total of one (1) hydroxyl groups bonded to an aliphatic carbon atom, optionally the radical R 5 and / or R 6 carries 1 or 2 aromatically bound hydroxyl groups or 1 nitrile, tertiary amino, carboxylic acid or sulfonic acid group, which are optionally present in the form of their salts, and the average functionality (F) of all structural components of the polyurethane (A), based on the functionalities which react with one another during the synthesis of the polyurethane (A) in an addition reaction, is 1.5 to 2.2.

专利号:US-4742052-A
优先权日:1981-07-15
标题:Antibacterial β-lactam compounds
发明人：SUNAGAWA MAKOTO; MATSUMURA HARUKI; INOUE TAKAAKI; ENOMOTO MASAO
权利人:SUMITOMO PHARMA
摘要:Novel beta -lactam compounds classified into penem compounds, a process for preparing the same and use of such beta -lactam compounds are disclosed. These beta -lactam compounds exhibit excellent antimicrobial activities useful as pharmaceuticals or they are important intermediates for the synthesis of compounds having antimicrobial activities.

专利号:US-4477660-A
优先权日:1982-11-16
标 题 :7-(S)-Acylaminocephalosporin sulfones and process
发明人：HALL DAVID A
权利人:LILLY CO ELI
摘要:This invention encompasses 7-(S)-acylamino-3-acetoxymethyl-3-cephem-4-carboxylic acid sulfones and the epimerization process for making them. The epimerization process employs an organic nitrogen base reagent having a pKa between about 9.0 to about 11.5. The compounds of this invention are intermediates in the synthesis of 1-oxa-β-lactam antibiotics.

专利号:US-4459405-A
优先权日:1982-11-16
标 题 :Desacetylcephalosporin sulfones
发明人：HALL DAVID A
权利人:LILLY CO ELI
摘要:7-(S)-Acylamino-3-hydroxymethyl-3-cephem sulfones are disclosed. These compounds are intermediates in the synthesis of 1-oxa β-lactam antibiotics.

专利号:US-4474879-A
优先权日:1982-11-16
标 题 :Process for 3-hydroxymethyl cephalosporin sulfones
发明人：HEINEY RICHARD E
权利人:LILLY CO ELI
摘要:This invention relates to a process for preparing 7-(S)-acylamino-3-hydroxymethyl-3-cephem-4-carboxylic acid sulfones and the salts and esters thereof. The instant process involves contacting a 7-(S)-acylamino-3-acetoxymethyl cephalosporin sulfone in an aqueous solution buffered from about pH 6 to about pH 8 with citrus acetylesterase, which is immobilized on silica gel. The 3-hydroxymethyl cephalosporin sulfones produced by the process of this invention are intermediates in the synthesis of 1-oxa β-lactam antibiotics.

专利号:WO-2011161615-A1
优先权日:2010-06-24
标题 :5-lipoxygenase inhibitors
发明人：VERMA ASHWANI KUMAR; MALHOTRA SANJAY; MARIMGANTI SRINIVASA; RAY ABHIJIT; GUPTA SUMAN; SRIVASTAVA PUNIT; DASTIDAR SUNANDA GHOSH
权利人:RANBAXY LAB LTD; VERMA ASHWANI KUMAR; MALHOTRA SANJAY; MARIMGANTI SRINIVASA; RAY ABHIJIT; GUPTA SUMAN; SRIVASTAVA PUNIT; DASTIDAR SUNANDA GHOSH
摘要:The present invention relates to pyrazole derivatives of formula 1 and to process as for their synthesis as 5-lipoxygenase (5-LO) inhibitors. The present invention also relates to pharmacological compositions containing these pyrazole derivatives, as well as, methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, Type I diabetes, psoriasis, allograft rejection, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders.