CAS: 33146-45-1; 2,6-Dichloro-1,1'-Biphenyl
该化合物是多氯联苯(PCB)家族的成员,该家族由不同程度氯化的合成有机化学品组成;多氯联苯10(PCB)具有联苯结构特征,含有联苯框架所附的10个氯原子,影响其物理和化学特性;该化合物一般无色,不光黄色固体或粘粘液,视温度和具体配方而定;多氯联苯10(包括PCB10)以其疏水性,低挥发性和高热稳定性而著称,使其在各种工业应用中有用,例如电绝缘和热传输液;然而,由于其环境持久性和潜在的健康风险,包括致癌性和内分泌干扰,多氯联苯在许多国家受到很大禁止或限制.多氯联苯10与其他多氯联苯一样,可以在食物链中生物累积,引起人们对其生态影响和人类接触的关切.适当的处理和处置对于减轻与该化学品有关的风险至关重要.
物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS08 & GHS09;
注释: Health hazard & Environment - 危险类别特定目标器官毒性-重复接触 类别2
水生急性毒性 类别1
水生慢性毒性 类别1 - 警示词Warning(警告)
- 危险描述H373 |长期或反复接触可能损害器官.
H400 |对水生生物毒性极大.
H410 |对水生生物毒性极大并具有长期持续影响. - 防范说明P260-P273-P391-P501
- 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
欧盟法规
C&L通报上下游产品
2,2',3,3',6,6'-hexachlorobiphenyl 1,2,3-trichlorobenzene benzene 1-bromo-2,6-dichlorobenzene m-chlorobiphenyl 2-chloro-1,1'-biphenyl N,N'-bis(biphenyl-2-yl)biphenyl-2,6-diamine 2, 2''',6,6'''-tetrachloro-1,1':2',1'':2'',1'''-quaterphenyl合成工艺路线路线简述
📜1,3-Dichloro-2-[(2,6-Dichlorophenyl)Methyl]-5-Methylbenzene 反应生成2,6-二氯联苯
参考文献:Friege,H.;Poppe,A.,Chemosphere,18,(1989) N-6,C. 1199-1206
标题:Friege,H.;Poppe,A.,Chemosphere,18,(1989) N-6,C. 1199-1206
海关参考信息
- 2903919090-氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-8952207-B2
优先权日:2007-09-11
标题:Copper-catalyzed C—H bond arylation
发明人：DAUGULIS OLAFS; DO HIEN-QUANG
权利人:DAUGULIS OLAFS; DO HIEN-QUANG; UNIV HOUSTON SYSTEM
摘要:The present invention is a one-step method for efficiently converting carbon-hydrogen bonds into carbon-carbon bonds using a combination of aryl halides, a substrate, and a copper salt as catalyst. This method allows faster introduction of complex molecular entities, a process that would otherwise require many more steps. This invention is particularly relevant for the organic synthesis of complex molecules such as, but not limited to, pharmacophores and explosives.
专利号:CN-105001344-B
优先权日:2015-07-24
标题 :There is synthesis and the application process of benzoic ether and carbanilate substituent straight chain starch derivative simultaneously
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1007/s00253-011-3334-z
摘要:Seo J, Kang SI, Kim M, Han J, Hur HG. Flavonoids biotransformation by bacterial non-heme dioxygenases, biphenyl and naphthalene dioxygenase. Appl Microbiol Biotechnol. 2011 Jul;91(2):219–28. doi: 10.1007/s00253-011-3334-z.
摘要:S116 | REFCCS | Collision Cross Section (CCS) Values from Literature | DOI:10.5281/zenodo.10932895
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). http://www.atsdr.cdc.gov/mrls/
📝 需求与反馈
尽可能描述清楚需求与问题信息
