CAS: 2524-37-0; Ethyl 2,4-Dihydroxy-6-Methylbenzoate

该化合物是属于苯甲酸酯类别的有机化合物,其2和4位置上有两个氢氧基基衍生物,6位置上有一个甲基组,乙基酯组在有机溶剂中的溶解性有助;该化合物的特点是中极性,它能够与极地和非极地环境互动;它可能展示生物活动,使其在制药和农业应用中引起兴趣;氢氧基组的存在表明氢联结的潜力,影响其物理特性,如熔点和沸点及其再活动;乙基苯基乙酸酯还可能参与各种化学反应,包括因现有功能组而导致的酯化和替代反应;

结构式图片

欧盟法规

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上下游产品

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合成工艺路线路线简述

    📜2-羟基-4-甲氧基-6-甲基苯甲酸乙酯置于三溴化硼体系中,用 二氯甲烷 用作溶剂,化学反应 0.17H,反应生成2,4-二羟基-6-甲基甲酸乙酯
    参考文献:Nematocidal Principles In "Oakmoss Absolute" And Nematocidal Activity Of 2,4-Dihydroxybenzoates
    标题:Nematocidal Principles In "Oakmoss Absolute" And Nematocidal Activity Of 2,4-Dihydroxybenzoates
    摘要:从橡树苔中提取的杀线虫物质被鉴定为 2,4-二羟基-3,6-二甲基苯甲酸甲酯(2),3-醛基-2,4-二羟基-6-甲基苯甲酸乙酯(4)和 5-氯-3-醛基-2,4-二羟基-6-甲基苯甲酸乙酯(7).根据它们的结构,测试了甲基至十四烷基的 2,4-二羟基苯甲酸酯的杀线虫活性,发现辛酯的活性最强(最小致死浓度=13 μm).
    Doi:10.1248/cpb.39.1043

    海关参考信息

    专利信息


    专利号:US-8481519-B2
    优先权日:2005-02-05
    标题 :Isolation of atraric acid, synthesis of atraric acid derivatives, and use of atraric acid and the derivatives thereof for the treatment of benign prostatic hyperplasia, prostate carcinoma and spinobulbar muscular atrophy
    发明人:HOFFMANN HANS-RAINER; MATUSCH RUDOLF; BANIAHMAD ARIA
    权利人:HOFFMANN HANS-RAINER; MATUSCH RUDOLF; BANIAHMAD ARIA; LOHMANN THERAPIE SYST LTS
    摘要:A method for isolating atraric acid from biological material, atraric acid derivatives, the chemical synthesis thereof, and the use of atraric acid and the derivatives thereof for treating or producing a medicament for treating benign prostate hyperplasia, prostate carcinoma or spinobulbar muscular atrophy is provided. In addition, a basic substance for the development of other agents used for treating benign prostate hyperplasia, prostate carcinoma, or spinobulbar muscular atrophy is provided.

    专利号:US-6900340-B2
    优先权日:2001-02-02
    标 题:Preparation of isocoumarin derivatives and intermediates for the synthesis thereof
    发明人:NAKATA MASAYA
    权利人:MERCIAN CORP
    摘要:A method of preparing optically active isocoumarin-3-yl-acetic acid derivatives represented by Formula (I): n n nwherein a specific isocoumarin-ketene derivative is subjected to an addition reaction with an optically active alcohol, and then the ester thus obtained is subjected to a hydrolysis reaction. An intermediate for synthesis used therein. A method of preparing isocoumarin-3-yl-acetic acid derivatives represented by Formula (III): n n nwherein a specific isocoumarin derivative is subjected to an addition reaction with carbon monoxide and oxygen in the presence of a transition metal catalyst. An intermediate for synthesis used therein.

    专利号:US-2009143466-A1
    优先权日:2005-02-05
    标题 :Isolation of Atraric Acid, Synthesis of Atraric Acid Derivatives, and Use of Atraric Acid and the Derivatives Thereof for the Treatment of Benign Prostatic Hyperplasia, Prostate Carcinoma and Spinobulbar Muscular Atrophy

    专利号:CA-2596634-C
    优先权日:2005-02-05
    标题 :Isolation of atraric acid, synthesis of atraric acid derivatives, and use of atraric acid and the derivatives thereof for the treatment of benign prostatic hyperplasia, prostate carcinoma and spinobulbar muscular atrophy

    专利号:ZA-200706107-B
    优先权日:2005-02-05
    标题 :Isolation of atraric acid, synthesis of atraric acid derivatives, and use of atraric acid and the derivatives thereof for the treatment of benign prostate hyperplasia, prostate carcinoma, and spinobulbar muscular atrophy

    专利号:JP-2008528648-A
    优先权日:2005-02-05
    标 题:Isolation of atralic acid, synthesis of atralic acid derivatives, and use of atralic acid and its derivatives for the treatment of benign prostatic hyperplasia, prostate malignancies and bulbar spinal muscular atrophy

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Xiong, Y.; Guo, R.; Zhang, G. Z., Science of Synthesis Knowledge Updates, (2021) 2, 429.
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