CAS: 1560-54-9; Allyltriphenylphosphonium Bromide

相似化合物

1530-32-1 2091-46-5 4736-60-1

上下游产品

allyl bromide triphenylphosphine 3-chloroprop-1-ene allyl alcohol 1,cis-3,trans-5,trans-11-tridecatetraen-7,9-diyne t,5t,11t-tetraen-7,9-diinTrideca-1,3t,5t,11t-tetraen-7,9-diin allyldiphenylphosphine ethyl 2,6,6-trimethyl-2,4-cyclohexadiene-1-carboxylate

烯丙醇,三苯基膦置于三甲基溴硅烷体系中,用 1,4-二氧六环 用作溶剂,以77%的收率获得烯丙基三苯基溴化膦
参考文献:由(杂)芳基甲醇一步法合成三苯基鏻盐
标题:由(杂)芳基甲醇一步法合成三苯基鏻盐
摘要:已经开发了两种从容易获得的苯甲醇及其杂环类似物合成取代鏻盐的方法.所开发的方案是互补的:发现将醇,三甲基溴化甲硅烷和三苯基膦直接混合在 1,4-二恶烷中,然后在 80 oc 下加热对酸敏感底物(例如水杨醇或糠醇)更有效作为仲苯甲醇,而包括顺序添加三甲基甲硅烷基溴和三苯基膦的一锅法可以为带有电中性或吸电子取代基的苯甲醇提供更高的收率.
Doi:10.1021/acs.Joc.1C00733

专利信息

专利号:WO-2023118045-A1
优先权日:2021-12-21
标 题:Process for the controlled synthesis of voclosporin
发明人：CORDOVILLA LOSADA CARLOS; FERNÃ?NDEZ SAINZ MARÃ?A YOLANDA; LORENTE BONDE-LARSEN ANTONIO
权利人:CURIA SPAIN S A U
摘要:The invention relates to a process for the preparation of mixtures of (E) and (Z)- isomers of Voclosporin in a controlled manner.

专利号:WO-9746543-A1
优先权日:1996-05-31
标题:Acetyl derivatives of thiazoles and analogues
发明人：PYNE STEPHEN GEOFFREY; UNG ALISON THAVARY
权利人:UNIV WOLLONGONG; PYNE STEPHEN GEOFFREY; UNG ALISON THAVARY
摘要:The present invention is directed to compounds useful in the treatment of autoimmune diseases and inflammatory diseases of general formula (I) wherein R1 is alkyl, alkenyl or alkynyl having from 1 to 6 carbons, phenyl, benzyl or phenethyl; R2 is H, C1 to C5 alkyl which can optionally be partially hydroxylated or the group (a) wherein n is from 0 to 4; and X, Y and Z are independently CH, N, NH, O or S, or a pharmaceutically acceptable ester or acid addition salt thereof, or a stereoisomer or a geometric isomer thereof, with the proviso that at least one of X, Y or Z is CH, that one and only one of X, Y and Z is NH, O or S and further that when Y is N or NH then Z is not N or NH. The present invention is also concerned with processes for the synthesis of the compounds and with methods of use of the compounds.

专利号:US-2025178999-A1
优先权日:2022-03-18
标 题:One step synthesis of 1-tetralone compounds and uses thereof in the preparation of (+)-tetralone abscisic acid (aba)
发明人：DIDDI NAVEEN; ABRAMS SUZANNE ROBERTA; LAI LEON
权利人:UNIV SASKATCHEWAN
摘要:The present application is related to a process for preparing 1-tetralone compounds such as compounds of Formula I by reacting a,; 3-unsaturated cyclic ketones that comprise two available hydrogens on the y carbon to the carbonyl with acrolein derivatives with heating in the presence of a suitable organic acid, a suitable organic amine base and suitable inert solvent. For example, the 1-tetralone compound is a tetralone derivative of abscisic acid (ABA).

专利号:US-3919253-A
优先权日:1972-09-20
标 题:Prostaglandin E{HD 1 {B intermediate, 2a-carboxy-3a-(1-hydroxyethyl)-5-oxocyclopentaneheptanoic acid,{65 -lactone, lower alkyl, and aralkyl esters, and processes of their preparation
发明人：KUO CHAN-HWA; TAUB DAVID; WENDLER NORMAN L
权利人:MERCK & CO INC
摘要:Disclosed is a novel stereospecific synthesis of Prostaglandin E1.

专利号:US-3965120-A
优先权日:1973-10-15
标 题:Prostaglandin E1 intermediate 3-carboxymethyl-4-methyl-2-1-carboxy-7-(loweralkoxy or aralkoxycarbonyl)-heptyl]-4-hydroxybutyric acid, γ-lactone, and processes of their preparation
发明人：KUO CHAN-HWA; TAUB DAVID; WENDLER NORMAN L
权利人:MERCK & CO INC
摘要:Disclosed is a novel stereospecific synthesis of Prostaglandin E 1 .

专利号:US-3891676-A
优先权日:1972-09-20
标题 :2-Alpha-carboxy-3-alpha(hydroxyethyl)-5-oxocyclopentane derivatives
发明人：KUO CHAN-HWA; TAUB DAVID; WENDLER NORMAN L
权利人:MERCK & CO INC
摘要:This invention relates to a new and novel synthesis of Prostaglandin E1 and more particularly to a synthesis which has a high degree of stereoselectivity at the points of generating the asymmetric centers of the molecule. It relates further to a synthesis in which the yields are high in the several reaction steps. The invention relates still further to the novel compounds obtained as intermediates in the prostaglandin E1 synthesis and the process for making such intermediates.