📜硬脂酸,乙炔置于马来酸酐,三丁基膦,Bis(η5-Cyclooctadienyl)Ruthenium体系中,用 甲苯 用作溶剂,化学反应 4.0H,以77%的收率获得硬脂酸酯乙烯基 参考文献:Ruthenium-Catalyzed Selective Addition Of Carboxylic Acids To Alkynes. A Novel Synthesis Of Enol Esters 标题:Ruthenium-Catalyzed Selective Addition Of Carboxylic Acids To Alkynes. A Novel Synthesis Of Enol Esters 摘要: Doi:10.1021/jo00387A024
专利号:WO-0134589-A1 优先权日:1999-11-05 标 题 :Semi-synthesis of baccatin iii from 9-dihydro-13-acetylbaccatin iii 发明人:ZAMIR LOLITA 权利人:ZAMIR LOLITA 摘要:The present invention relates to a semi-synthetic process to convert a naturally occurring taxane into a suitable starting material for the synthesis of paclitaxel and related compounds. Specifically, the present invention relates to a process for the conversion of 9-dihydro-13-acetylbaccatin III into baccatin III which can then be used as starting material for the synthesis of taxane derivatives such as paclitaxel, docetaxel, cephalomannine and other taxanes structurally related to baccatin III.
专利号:US-8053522-B2 优先权日:2006-02-28 标题 :Synthesis of polyester-graft-poly(meth)acrylate copolymers 发明人:LOEHDEN GERD; BALK SVEN; BRAND THORSTEN; BRENNER GABRIELE; ARNOLD THOMAS; BAUMANN CORNELIA 权利人:EVONIK ROEHM GMBH 摘要:The present invention relates to a novel synthesis of (meth)acrylate-grafted polyesters and their action as compatibilizers.
专利号:US-7189849-B2 优先权日:1997-02-10 标 题:Synthesis of acyclic nucleoside derivatives 发明人:LEANNA M ROBERT; RASMUSSEN MICHAEL; HANNICK STEVEN M; TIEN JIEN-HEH J; LUKIN KIRILL A; TIAN ZHENPING; CHANG SOU-JEN; CURTY CYNTHIA B; NARAYANAN BIKSHANDARKOIL A; BELLETTINI JOHN; SHELAT BHADRA; SPITZ TIFFANY 权利人:MEDIVIR AB 摘要:Novel processes towards the synthesis of the antiviral valomaciclovir stearate in which an esterified guanine acetal is reduced to the corresponding alcohol, reacted with an activated amino acid and N-deprotected. The esterified guanine acetal is prepared from a 9-guanine derivative bearing an acyclic hydroxymethylbutylacetal. The processes are amendable to one-pot reactions.
专利号:WO-9723519-A1 优先权日:1995-12-21 标题:Synthesis of aqueous, anionic, amino acrylate polymers 发明人:DAS SURYYA K; KILIC SONER 权利人:PPG INDUSTRIES INC 摘要:Disclosed is a method of making aqueous, anionic amino polymers in water from olefinically unsaturated monomers including amine-containing monomers, but substantially without the inclusion of acid-group containing monomers. The polymerization of the amino polymer is carried out in the presence of a carboxy functional azo initiator dissolved in water by neutralization of acid groups present on the initiator. The polymer is useful in single-package or two-package coating compositions having pH above 7.0 that may be cured with polyisocyanates or polyepoxides.
专利号:US-5541273-A 优先权日:1993-11-12 标 题 :Method for preparing poly(vinyl trifluoroacetate) and poly(vinyl trifluoroacetate/vinyl ester) in the absence of chlorofluorocarbon solvent 发明人:EIAN GILBERT L 权利人:MINNESOTA MINING & MFG 摘要:A method for the production of poly(vinyl trifluoroacetate) and copolymers thereof with vinyl esters is described. Poly(vinyl trifluoroacetate) (PVTFA) is obtained in essentially quantitative yield under mild conditions by using non-chlorofluorocarbon solvents comprising siloxanes or perfluorinated fluid. Hexamethyl disiloxane is a particularly useful example of such solvents. Synthesis of syndiotactic PVTFA on a commercial scale without the use of environmentally-harmful solvents is made possible by the invention, which provides a convenient commercial route to syndiotactic polyvinyl alcohol.
专利号:US-11859029-B2 优先权日:2018-07-25 标 题 :Methods of synthesis of homopolymers and non-homopolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties in an aqueous medium 发明人:DEANE OLIVER JOHNATHAN; MUSA OSAMA M; ARMES STEVEN PETER; FERNYHOUGH ALAN; GIBSON REBECCA ROISIN 权利人:ISP INVESTMENTS LLC 摘要:The invention provides a method for preparation of homopolymers and non-homopolymers comprising polymerizing in an aqueous medium a monomer comprising at least one acryloyl moiety and at least one functionalized or unfunctionalized lactam moiety, and optionally at least one hydrophilic or hydrophobic comonomer, in the presence of at least one chain transfer agent and at least one non-radiation initiator. Exemplary diblock polymers prepared by the method have the structure:where subscripts x, y, and z and variables R, R8, R9 and R10 are described herein.
[参考文献]: Eunae Cho, Et Al. Regioselective Self-Acylating Cyclodextrins In Organic Solvent. Sci Rep. 2016 Mar 29:6:23740.
合成参考文献
参考文献:10.1007/s11095-006-9072-8 摘要:Hastedt JE, Wright JL. Percolative Transport and Cluster Diffusion Near and Below the Percolation Threshold of a Porous Polymeric Matrix. Pharmaceutical Research. 2006 Aug 24;23(10):2427–40. doi: 10.1007/s11095-006-9072-8.