CAS: 638-41-5; Pentyl Carbonochloridate

相似化合物

6092-54-2 26272-90-2 58906-62-0

上下游产品

phosgene pentan-1-ol bis(trichloromethyl) carbonatedipentyl carbonate (butane-1-sulfonyl)-carbamic acid pentyl ester carbonic acid-(2-nitro-phenyl ester)-pentyl ester 2-hydroxy-4-pentyloxycarbonylamino-benzoic acid

光气,戊醇 以 苯 作为反应溶剂,化学反应生成 氯甲酸正戊酯
参考文献:N-羟基氨基甲酸酯的合成及一些反应
标题:N-羟基氨基甲酸酯的合成及一些反应
摘要:羟胺和氯甲酸烷基酯在碱性介质中反应,以形成ñ-,-No-二-,和nno-三烷氧羰基羟胺,依次.n-甲基羟胺类似地得到n-和no-二烷氧基羰基-N-甲基-羟胺,O-甲基羟胺产生n-和nn-二烷氧基羰基-O-甲基羟胺.n-苯基羟胺与1当量的氯甲酸乙酯反应,得到n-羟基-N-苯基氨基甲酸酯.盐酸羟胺和氯甲酸乙酯产生产物,其变为羟基氨基甲酸酯.n-羟基氨基甲酸酯烷基和羟基脲得到o-黄羟基衍生物.所述ñ-Hydroxycarbamates用含水四氰二钾(II)而形成二钾tricyanonitrosylnickelate(II).在这些羟氨基衍生物的酸和碱水解过程中,没有证据表明发生了洛森型重排.讨论了可能的水解机理.
DOI:10.1039/j39660000346

专利信息

专利号:US-2003083352-A1
优先权日:2000-07-31
标 题 :Synthesis of imidazole intermediates
发明人：HELAL CHRISTOPHER J
权利人:PFIZER
摘要:The invention provides a method for synthesis of compounds of formula n n n wherein R 1 and R 19 are as defined. Compounds of formula 12 are useful as intermediates for synthesizing compounds having pharmacological activity inhibiting cdk5, cdk2, and GSK-3.

专利号:US-6472534-B2
优先权日:1999-10-21
标 题:Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors
发明人：BORER BENNETT C; ZOOK SCOTT E; BUSSE JULIETTE K
权利人:AGOURON PHARMA
摘要:Methods for the preparation of chemical intermediates in the synthesis of HIV-protease inhibitors related to and including nelfinavir mesylate are disclosed. The method of this invention comprises converting tetrohydran derivatives into oxazolines to provide key reaction intermediates for the preparation of nelfinavir. Also disclosed is a method for the preparation of a chiral amino alcohol from an epoxy-tetrahydrofuran.

专利号:US-4192798-A
优先权日:1978-11-20
标题:Rapid, large scale, automatable high pressure peptide synthesis
发明人：FULLER WILLIAM D; GOODMAN MURRAY; VERLANDER MICHAEL S
权利人:BIORESEARCH INC
摘要:In the method for the synthesis of a polypeptide chain on an insoluble solid support wherein an amino acid is introduced into a reactor packed with an insoluble solid support containing substituent groups reactive with said amino acid, coupling said amino acid to said support by condensation reaction with said reactive substituent groups, introducing a second similar or dissimilar amino acid into said reactor and coupling said second amino acid to said first amino acid and repeating the process until the desired polypeptide is obtained, the improvement wherein a high pressure flow system is used and the reaction pressure in said reactor during said synthesis is at least 200 psi up to 10,000 psi or more, in order to obtain rapid reactions and quantitative yields of the desired products.

专利号:US-6114569-A
优先权日:1997-02-12
标 题:Efficient synthesis of A 1,4-dihydro-2H-3,1-benzoxazin-2-one
发明人：FREY LISA F; GRABOWSKI EDWARD J J; TILLYER RICHARD D
权利人:MERCK & CO INC
摘要:An efficient method for the preparation of a compound of (-)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one, also known as DMP-266, a reverse transcriptase inhibitor is achieved using a cyclization reaction of the amino alcohol intermediate with an alkyl or aryl chloroformate and a base.

专利号:US-7794683-B1
优先权日:2006-04-14
标 题:Method of making functionalized carbon nanotubes
发明人：FOROHAR FARHAD; WHITAKER CRAIG; KOPPES WILLIAM M
权利人:US NAVY
摘要:The present invention relates to methods for the preparation of a carbon nanotube from an amino-functionalized carbon nanotube via an amino oxidation reaction. The carbon nanotube includes nitrogen based functional groups that are covalently attached to lattice carbons of the carbon nanotube, directly or via a chemical linker. The synthetic methods of the present invention allow the nitrogen based functional groups to be attached selectively to one of two distinct regions of the carbon nanotube, and thus enable the synthesis of a carbon nanotube having nitrogen based functional groups substantially concentrated on the ends and/or the sidewall of the carbon nanotube.

专利号:US-5270468-A
优先权日:1992-04-01
标 题 :2- and 3- amino azido derivatives of 1,5-iminosugars
发明人：KHANNA ISH K; MUELLER RICHARD A; WEIER RICHARD M; STEALEY MICHAEL A
权利人:SEARLE & CO
摘要:Novel derivatives of 1-deoxynojirimycin are disclosed which have amino or azido substituents at C-2 and/or C-3. These compounds are useful inhibitors of lentiviruses. Methods of chemical synthesis of these derivatives and intermediates therefor are also disclosed.