CAS: 53555-66-1; 3,4,5-Trichlorobiphenyl

该化合物是一种属于多氯联苯类别的氯化双联苯化合物,其特点是,在联苯结构中存在三个替代氯原子,特别是在3,4和5个位置上,该化合物在室内温度下一般没有色素,没有黄色,而且以其疏水性闻名,使其在水中不溶解,但在有机溶剂中可溶解. 3,4,5-三氯联苯具有热稳定性和抗降解性,这促使其长期存在于环境中.该化合物一直被用于各种工业用途,包括作为电气设备中的电动液体和热传输媒介.然而,由于其毒性特性和潜在的环境影响,包括生物蓄积和内分泌干扰,许多国家对其生产和使用实行了严格的管制或禁止.在处理这一化合物时,安全防范措施至关重要,因为其潜在的健康风险.

英文名称3,4,5-Trichlorobiphenyl
中文名称3,4,5-三氯联苯
IUPAC名称1,2,3-trichloro-5-phenylbenzene
其它别名3,4,5-Trichloro-1,1'-biphenyl; 3,4,5-Trichlorobiphenyl; PCB 38
CAS编号53555-66-1
MFCD编号:MFCD00152905
FDA UNII编号:7TJ4JMT31P
分子式:C12H7Cl3分子量:257.54
产品CID: 2495534
产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃

相似结构搜索
InChIKey: BSFZSQRJGZHMMV-UHFFFAOYSA-N
1S/C12H7Cl3/c13-10-6-9(7-11(14)12(10)15)8-4-2-1-3-5-8/h1-7H
计算化学: 氢键受体数*氢键供体数0.0可旋转键数1.0

MSDS等安全信息

危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website.
安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)

上下游产品

3,4,5-trichloroaniline benzene PCB 61 5-bromo-1,2,3-trichloro-benzene biphenyl 3,4-dichlorobiphenyl

合成工艺路线路线简述

📜3,4,5-三氯溴苯,苯硼酸置于2-双环己基膦-2',6'-二甲氧基联苯,Potassium Phosphate,Palladium Diacetate体系中,用甲苯作为反应溶剂,化学反应 6.0H,以63%的收率获得产物3,4,5-三氯联苯
参考文献:Organic Electroluminescence Device And Polycyclic Compound For Organic Electroluminescence Device
标题:Organic Electroluminescence Device And Polycyclic Compound For Organic Electroluminescence Device
摘要:一种有机电致发光器件包括第一电极,设置在第一电极上的空穴传输区域,设置在空穴传输区域上的发射层,设置在发射层上的电子传输区域,设置在发射层上的电子传输区域,并设置在电子传输区域上的第二电极,其中发射层包括由式1表示的多环化合物,以获得高发光效率.