CAS: 3619-02-1; Ac-Ala-Ome
该化合物是一个化学化合物,其结构特征包括乙酰基,氨氨酸丙胺和甲基酯功能组,该化合物一般是白色的脱白固体,在水和甲醇等极地溶剂中溶解,使其在各种生物化学应用中有用;Ac-Ala-OMe是peptide合成的一个构件,并经常用于与蛋白质结构和功能有关的研究,因为其具有模拟自然氨酸的能力.乙酸组的存在增强了其稳定性和溶性,而甲基酯可以促进将氨酸纳入更大的peptide链.此外,Ac-Ala-OMe可能展示生物活动,使其在药理学研究中引起兴趣.许多氨基酸衍生物与许多氨基酸衍生物一样,必须谨慎地处理这一化合物,在实验室环境上遵循适当的安全规程.
- 英文名称Ac-Ala-Ome
- 中文名称N-乙酰基-L-丙氨酸甲酯
- IUPAC名称methyl acetyl-L-alaninate
- 其它别名N-乙酰基-L-丙氨酸甲酯; (S)-Methyl 2-Acetamidopropanoate
- CAS编号3619-02-1
- MFCD编号:MFCD00038239
- 分子式:C6H11NO3分子量:145.16
- 产品CID: 2254866
- 产品分类有机原料→分子砌块→手性化合物→手性砌块
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📜2-乙酰氨基丙烯酸置于bis(1,5-Cyclooctadiene)Rhodium(I) Trifluoromethanesulfonate (R)-N-Diphenylphosphino-N-Methyl-1-[(S)-2-(Diphenylphosphino)Ferrocenyl]Ethylamine,氢气体系中,用 四氢呋喃 作为反应溶剂,25.0 °C,68.95 Kpa 条件下,反应 24.0H,反应生成 N-乙酰基-L-丙氨酸甲酯
参考文献:Synthesis And Application Of Phosphinoferrocenylaminophosphine Ligands For Asymmetric Catalysis
标题:Synthesis And Application Of Phosphinoferrocenylaminophosphine Ligands For Asymmetric Catalysis
摘要:[graphics]A New Class Of Bidentate Ligands Utilizing A Phosphine-Aminophosphine Structure Has Been Prepared On A Ferrocenylethyl Backbone In A Straightforward And Scalable Fashion From Acetylferrocene. The Unique Property Of The Alpha-Ferrocenyl Carbonium Ion That Allows The Replacement Of A Variety Of "Leaving Groups" With Retention Of Configuration Greatly Facilitates The Synthesis,And A Number Of Ligands Have Been Prepared By Varying The Nitrogen And Phosphorus Substituents On The Aminophosphine. These Readily Prepared Phosphinoferrocenylaminophosphines,Known As Bophoz Ligands,Show Surprising Hydrolytic And Air Stability,With No Degradation After 3 Years Open To The Air. The Rhodium Complexes Of These Ligands Show Exceedingly High Enantioselectivities (Generally >95% Ee) And Activities Often In Excess Of 50 000 Catalyst Turnovers Per Hour For The Asymmetric Hydrogenation Of A Wide Variety Of Dehydro-Alpha-Amino Acid And Itaconic Acid Derivatives. They Also Show High Activity And Good To Excellent Enantioselectivity For The Hydrogenation Of A Number Of Alpha-Ketoesters.
DOI:10.1021/jo048312Y
海关参考信息
- 2905121000-正丙醇
2912110000-甲醛
2912120000-乙醛
2915110000-甲酸 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
