CAS: 2136-99-4; 2,2',3,3',5,5',6,6'-Octachlorobiphenyl
该化合物是一种高度氯化的双苯化合物,其特点是其稳定的芳香结构和耐降解性;这种八氯化同族元素的挥发性和亲脂性较低,适合用于研究的专门应用,特别是在环境和毒理学研究中;其持久性允许用作分析化学的参考标准,帮助在复杂的基质中检测和量化多氯联苯(PCB);该化合物的界定明确的化学特性确保了实验环境中的再生性,而其结构上的僵硬性则有助于了解氯化程度较高的多氯联苯的行为;处理要求严格遵守安全议定书,因为其潜在的生物累积和毒性影响.
- 英文名称2,2',3,3',5,5',6,6'-Octachlorobiphenyl
- 中文名称2,2',3,3',5,5',6,6'-八氯联苯
- IUPAC名称1,2,4,5-tetrachloro-3-(2,3,5,6-tetrachlorophenyl)benzene
- 其它别名Biphenyl,2,2',3,3',5,5',6,6'-°Ctachloro- (7CI,8CI); 2,2',3,3',5,5',6,6'-°Ctachlorobiphenyl; 2,3,5,6,2',3',5',6'-°Ctachlorobiphenyl
- CAS编号2136-99-4
- MFCD编号:MFCD00152686
- FDA UNII编号:79G6GKQ4GC
- 分子式:C12H2Cl8分子量:429.77
- 产品CID: 1102154
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
物理性质
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
2,3,5,6,2',3',5',6'-°Ctachloro-benzidine 1,2,4,5-Tetrachloro-3-iodobenzene 2,2',6,6'-tetrachlorobiphenyl 1,2,4,5-tetrachlorobenzene合成工艺路线路线简述
📜3,5-二氯硝基苯置于盐酸,Sodium Hydroxide,乙醇,硫酸,氯,溶剂黄146,锌体系中,化学反应生成2,2',3,3',5,5',6,6'-八氯联苯
参考文献:Van Roosmalen,Recueil Des Travaux Chimiques Des Pays-Bas,1934,Vol. 53,P. 359,362
标题:Van Roosmalen,Recueil Des Travaux Chimiques Des Pays-Bas,1934,Vol. 53,P. 359,362
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:S116 | REFCCS | Collision Cross Section (CCS) Values from Literature | DOI:10.5281/zenodo.10932895
摘要:S50 | CCSCOMPEND | The Unified Collision Cross Section (CCS) Compendium | DOI:10.5281/zenodo.2658162
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). http://www.atsdr.cdc.gov/mrls/
📝 需求与反馈
尽可能描述清楚需求与问题信息
