CAS: 207738-08-7; 3,3',5,5'-Tetramethyl-[1,1'-Biphenyl]-4,4'-Diamine Dihydrochloride Xhydrate

专利信息

专利号:US-5712286-A
优先权日:1994-10-06
标 题 :Naphthyridine derivatives
发明人：GILL JULIE CAROLYN; LESLIE BRUCE WILLIAM
权利人:KNOLL AG
摘要:PCT No. PCT/EP95/03769 Sec. 371 Date Mar. 24, 1997 Sec. 102(e) Date Mar. 24, 1997 PCT Filed Sep. 23, 1995 PCT Pub. No. WO96/11198 PCT Pub. Date Apr. 18, 1996Compounds of formula (I) including pharmaceutically acceptable salts thereof in which R1 represents a C1-6 alkyl group; R2 represents a group of the formula COOR4 in which R4 represents a C1-5 alkyl group; and R3 represents a group of formula COOR5 in which R5 represents a C1-5 alkyl group are disclosed, which are anti-rheumatic agents and are useful as modulators of cytokine synthesis, immunomodulatory agents, anti-inflammatory agents and anti-allergic agents. Compositions containing these compounds and processes to make these compounds are also disclosed.

专利号:US-5854257-A
优先权日:1994-10-06
标 题:Naphthyridinone derivatives
发明人：ARMITAGE BERNARD JOHN; LESLIE BRUCE WILLIAM
权利人:KNOLL AG
摘要:PCT No. PCT/EP95/03808 Sec. 371 Date Mar. 24, 1997 Sec. 102(e) Date Mar. 24, 1997 PCT Filed Sep. 26, 1995 PCT Pub. No. WO96/11199 PCT Pub. Date Apr. 18, 1996Compounds of formula I I including pharmaceutically acceptable salts thereof in which R1 represents a phenyl C1-6 alkyl group (in which the phenyl ring is optionally substituted by one or more of the following: halo, a C1-4 alkyl group, a C1-4 alkoxy group, hydroxy or trifluoromethyl) and the alkyl chain is optionally substituted by one or more C1-2 alkyl groups; R2 represents a C2-6 alkoxycarbonyl group; and R3 represents hydrogen or halo are disclosed, which are antirheumatic agents and are useful as modulators of cytokine synthesis, immunomodulatory agents, antiinflammatory agents and anti-allergic agents. Compositions containing these compounds and processes to make these compounds are also disclosed.

专利号:CN-115612114-A
优先权日:2021-07-14
标 题:Method and application of copolymer film and its enzymatic self-assembly synthesis