CAS: 18840-47-6; Gepefrine
该化合物是一种手淫酚化合物,其特点是带有一个(S)配置的氨基丙基侧链.这种结构元素由于其立体化学特性和功能性多功能性,可以应用于非对称合成,制药中间体和离子设计.酚组提供了进一步衍生的场所,而主要矿能参与凝结或协调化学.它的对应纯度对于高选择性地生产光学活性化合物是有利的.该化合物在标准条件下的稳定性和与普通有机溶剂的兼容性增强了其在研究和工业过程中的效用.对于受控反应来说,它是一个有价值的药用和合成化学建筑块.
- 英文名称Gepefrine
- 中文名称吉普林
- 其它别名Phenol,3-(2-aminopropyl)-, (S)-; Phenol, m-(2-aminopropyl)-, (S)-(+)- (8CI); (a-S)-(+)-a-Methyl-m-tyramine; Gepefrine; d-a-Methyl-m-tyramine
- CAS编号18840-47-6
- MFCD编号:MFCD20458539
- FDA UNII编号:V51RRX51VH
- 分子式:C9H13NO分子量:151.21
- 产品CID: 955984
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
物理性质
MSDS等安全信息
合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物
2918290000-其他含酚基羧酸 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.
专利号:US-10814013-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:AU-2007308022-A1
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
专利号:US-2008107598-A1
优先权日:2006-10-05
标 题:Efficient Synthesis of Chelators for Nuclear Imaging and Radiotherapy: Compositions and Applications
专利号:AU-2007308022-B2
优先权日:2006-10-05
标题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
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主要参考文献
[参考文献]: Bachour G, Et Al. [参考文献]: Z Kardiol. 1985 Apr;74(4):228-33. German.[参考文献]: Lossnitzer K, Et Al. Vergleichende Untersuchungen Antihypotensiv Wirksamer Sympathikomimetika Im Kipptisch-Versuch [参考文献]: Fortschr Med. 1980 Aug 7;98(29):(1133-6). German.
[参考文献]: Peters Ft, Et Al. Drug Testing In Blood: Validated Negative-Ion Chemical Ionization Gas Chromatographic-Mass Spectrometric Assay For Determination Of Amphetamine And Methamphetamine Enantiomers And Its Application To Toxicology Cases. Clin Chem. 2002 Sep;48(9):1472-85.
合成参考文献
参考文献:10.1016/0006-2952(61)90060-0
摘要:UDENFRIEND S, CONNAMACHER R, HESS SM. On the mechanism of release of norepinephrine by alpha-methyl-m-tyrosine and alpha-methyl-m-tyramine. Biochem Pharmacol. 1961 Dec;8():419–21. doi: 10.1016/0006-2952(61)90060-0.
参考文献:10.1007/978-94-011-3804-8_7
摘要:Seyffart G. G. 1991. In: Drug Dosage in Renal Insufficiency.
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