相似化合物
19785-39-8 15679-13-7 541-58-2欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
2-ethenyl-4-methyl-1,3-thiazole 2-ethyl-4-methyl-3-thiazoline 1-(4-methyl-1,3-thiazol-2-yl)ethan-1-one thiopropanamide 2-ethyl-3-(4-bromo-β-hydroxyimino-phenethyl)-4-methyl-thiazolium; bromide b]thiazole3,7-dimethyl-6-phenyl-pyrrolo[2,1-b]thiazole b]thiazole6-(4-methoxy-phenyl)-3,7-dimethyl-pyrrolo[2,1-b]thiazole b]thiazol-5-yl)-ethanone1-(3,7-dimethyl-6-phenyl-pyrrolo[2,1-b]thiazol-5-yl)-ethanone 2-乙酰基-4-甲基噻唑 反应生成2-乙基-4-甲基噻唑
参考文献:Metzger; Koether,Bulletin De La Societe Chimique De France,1953,P. 702,705
标题:Metzger; Koether,Bulletin De La Societe Chimique De France,1953,P. 702,705
专利信息
专利号:US-6586453-B2
优先权日:2000-04-03
标 题:Substituted thiazoles and the use thereof as inhibitors of plasminogen activator inhibitor-1
发明人:DHANOA DALE S; RYAN DECLAN E; DECKMAN INGRID; SAPIENZA ANTHONY
权利人:DIMENSIONAL PHARM INC
摘要:The present invention relates to the use of aminothiazole derivatives of Formula I of as inhibitors of PAI-1, and to novel classes of aminothiazole derivatives, their synthesis and their use as inhibitors of PAI-1. It has been discovered that compounds of Formula I:or a solvate, hydrate or a pharmaceutically acceptable salt thereof, whereinY, Ar1, Ar2, R1, R2, Z, m and n are described in the specification, inhibit plasminogen activator inhibitor-1 (PAI-1). These compounds can be used in the prophylaxis or for the treatment of thrombosis, angina pectoris, cerebral infarction, myocardial infarction, pulmonary infarction, intra-atrial thrombus in atrial fibrillation, deep venous thrombus, disseminated intravascular coagulation syndrome, diabetic complications, restenosis and stroke.
专利号:US-7256177-B2
优先权日:2003-06-17
标题 :Lincomycin derivatives possessing antibacterial activity
发明人:LEWIS JASON G; ANANDAN SAMPATH K; O'DOWD HARDWIN; GORDEEV MIKHAIL F
权利人:VICURON PHARM INC
摘要:Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including Gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.
专利号:US-7361743-B2
优先权日:2004-02-11
标 题 :Lincomycin derivatives possessing antibacterial activity
发明人:LEWIS JASON G; ANANDAN SAMPATH K; O'DOWD HARDWIN; GORDEEV MIKHAIL F; LI LIANSHENG
权利人:PFIZER
摘要:Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including Gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.
专利号:US-7199106-B2
优先权日:2003-06-17
标题 :Lincomycin derivatives possessing antimicrobial activity
发明人:LEWIS JASON G; ANANDAN SAMPATH-KUMAR; O'DOWD HARDWIN; GORDEEV MIKHAIL F
权利人:VICURON PHARM INC
摘要:Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. The compounds of the subject invention may exhibit potent activities against bacteria, including gram positive organisms, and may be useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.