CAS: 10521-91-2; 5-Phenylpentan-1-Ol

该化合物是有机有机体化合物,其特点是存在一种碱酸功能组和一种酸酯,这种化合物一般显示白色至白色固态外表,在二氯甲烷和四氢呋喃等有机溶剂中可溶解,其结构特征是附于一个粉状链的联苯组,它有助于其在有机合成中的再活性和潜在应用,特别是在交叉反应和作为制药的建筑块.这种碱酸功能允许与二醇的可逆结合,使其在各种化学变异和感应应用中有用.此外,该化合物的稳定性和再活性可能受到诸如pH和其他功能组的存在等因素的影响.与许多有机体化合物一样,在处理过程中,由于潜在的反应性和毒性,应当采取安全防范措施.

结构式图片

相似化合物

2270-20-4 20620-59-1 2430-16-2

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

oxirane 3-phenylpropylmagnesium bromide 5-phenyl-n-valeric acid methyl ester 5-phenylpenta-2,4-dien-1-ol (5-bromopentyl)benzene 5-phenylpent-1-ene 5-chloropentylbenzene phenyl-carbamic acid-(5-phenyl-pentyl ester)

合成工艺路线路线简述

  • 合成目标产物 5-Phenyl-1-Pentanol 主要起始原料 Tetrahydrofuran And Benzyl Bromide
  • (文献来源)合成步骤主要原料 Tetrahydrofuran 和 Benzyl Bromide
📜5-苯基戊酰氯置于lithium Aluminium Tetrahydride体系中,用 乙醚 用作溶剂,化学反应生成苯戊醇
参考文献:254.一些单烷基苯的合成
标题:254.一些单烷基苯的合成
摘要:
Doi:10.1039/jr9600001254

海关参考信息

专利信息


专利号:US-7173021-B2
优先权日:2004-09-02
标题:Synthesis of temozolomide esters as potent anticancer pro-drugs for topical and transdermal applications in treatments of cancers
发明人:WANG YONGFENG; CONWAY BARBARA R; SUPPASANSATORN PANASSAYA
权利人:TIANJIN NORTH PHARM SCI TECH C
摘要:This invention relates to the use of temozolomide esters (4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylate esters) Formula 1 as potent anticancer pro-drugs for treatment of cancers by topical and transdermal applications, and to a novel process for synthesis of temozolomide esters by a direct esterification of temozolomide acid (3,4-dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic acid) with a halogeno-aliphatic compound in presence of a base, or with an alcohol in presence of a dehydrate agent

专利号:US-4412958-A
优先权日:1981-10-16
标 题:Stereospecific synthesis of 5-phenyl-2S-pentanol
发明人:CUE JR BERKELEY W; MOORE BERNARD S
权利人:PFIZER
摘要:5-Phenyl-2S-pentanol is synthesized stereospecifically from S ethyl lactate. The method provides easily purified 5-phenyl-2S-pentanol useful in the synthesis of central nervous system active (CNS) agents such as levonantradol.

专利号:US-2007293456-A9
优先权日:2004-12-30
标题:Method for the synthesis of 3-substituted indolizine and benzoindolizine compounds
发明人:HAYFORD ANTHONY; KALOKO JOSEPH
权利人:HAYFORD ANTHONY; KALOKO JOSEPH
摘要:A method of making a compound of Formula I: n n ncomprises reacting a compound of Formula II n n nwith a compound such as R 1 OH or R 1 SH, to produce said compound of Formula I. Compounds of Formula I are useful, among other things, as dyes, spectral sensitizers, glycosidase inhibitors, and as antibacterial, antiviral, and anti-inflammatory agents.

专利号:US-2004053999-A1
优先权日:1997-09-17
标题 :Novel compounds and methods for synthesis and therapy
发明人:BISCHOFBERGER NORBERT W; DAHL TERRENCE C; HITCHCOCK MICHAEL J M; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; MILLS ROGER G; WILLIAMS MATTHEW A
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

专利号:US-2022411449-A1
优先权日:2019-11-13
标 题 :Method for Preparing Heteroleptic Triarylbismuthanes and Compounds Produced by the Same
发明人:HYVL JAKUB; LEHRER AXEL
权利人:UNIV HAWAII
摘要:A method for controlling dismutation in the synthesis of a heteroleptic triarylbismuthane is provided as are compounds produced by such a method and use of the same to inhibit the replication of microorganisms.

专利号:US-6225341-B1
优先权日:1995-02-27
标 题:Compounds and methods for synthesis and therapy
发明人:BISCHOFBERGER NORBERT W; KIM CHOUNG U; LEW WILLARD; LIU HONGTAO; WILLIAMS MATTHEW A
权利人:GILEAD SCIENCES INC
摘要:Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

[参考文献]: H G Abbas, Et Al. Synthesis Of [参考文献]: Shintaro Tobiishi, Et Al. Methoxy- And Fluorine-Substituted Analogs Of O-1302: Synthesis And In Vitro Binding Affinity For The Cb1 Cannabinoid Receptor. Chem Pharm Bull (Tokyo). 2007 Aug;55(8):1213-7.

合成参考文献


摘要:Schobert, R.; Hölzel, C.; Barnickel, B., Science of Synthesis, (2010) 47, 33.
摘要:Braverman, S.; Cherkinsky, M., Science of Synthesis Knowledge Updates, (2014) 3, 240.
摘要:Clark, K. F.; Dimitrova, D.; Murphy, J. A., Science of Synthesis, (2020) , 2.
摘要:Ying, J.; Wu, X.-F., Science of Synthesis: Knowledge Updates, (2024) 1, 284.
摘要:Dong, X.; Qin, H.; Chen, Y., Science of Synthesis: Hypervalent Halogens in Organic Synthesis, (2025) .
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