CAS: 99438-28-5; (+)-B-Methoxydiisopinocampheylborane

该化合物是一种人工有机有机体化合物,其用途在不对称合成中,特别是在有机化学领域.该化合物的特性是将原原原子粘合成两个异丙基丙基甲基基和甲氧基组,有助于其独特的立体化学特性.水合物的存在表明它含有水分子,可影响其溶解性和再活性.一般而言,该化合物被用作各种反应的试剂,包括水吸和藻类酒精合成,展示其在促进形成碳-碳联系方面的作用.其特性允许有选择地形成抗生素,使其在制药和精细化学剂的生产中具有价值.该化合物的处理一般是谨慎的,因为种的再活性,应当储存在适当的条件下,以保持其稳定性和有效性.

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21947-87-5 21932-54-7 112246-73-8

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methanol L-diisopin°Campheylborane (-)-α-pinene (3R,4S)-3-(diphenylamino)-1-°Cten-4-ol (3R,4S)-3-(diphenylamino)-1-undecen-4-ol (1S,2R)-2-(diphenylamino)-1-phenyl-3-buten-1-ol (2S,3R)-3-(diphenylamino)-4-pentan-2-ol

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    专利信息


    专利号:US-7339066-B1
    优先权日:2006-05-31
    标题 :Intermediates for the synthesis of polypropionate antibiotics
    发明人:PARKER KATHLYN; CAO HUANYAN
    权利人:UNIV NEW YORK STATE RES FOUND
    摘要:The invention relates to intermediate compounds of the formula n nwherein R 1 is H or a protecting group, R 2 and R 3 each independently represent H, methyl, or a leaving group, provided that at least one, but not both, of R 2 and R 3 is a leaving group. The intermediate compounds are useful for the synthesis of discodermolide, its derivatives, and related compounds.

    专利号:US-5463131-A
    优先权日:1994-06-30
    标题 :Synthesis of organohaloboranes and alkoxyorganoboranes
    发明人:BURKHARDT ELIZABETH R
    权利人:MINE SAFETY APPLIANCES CO
    摘要:A one-step process is provided for the synthesis of organohaloboranes, including diisopinocampheylchloroborane, and alkoxyorganoboranes. The present process does not utilize a thermally unstable ether adduct or a malodorous dimethyl sulfide adduct as required in prior processes. In general, the organohaloboranes are synthesized in a single reactor by reacting olefin(s) and/or alkyne(s) with boron trihalide and diborane. Alkoxyorganoboranes are synthesized in a single reactor by reacting olefin(s) and/or alkyne(s) with alkylborate and diborane.

    专利号:WO-2014108526-A1
    优先权日:2013-01-11
    标题 :Synthetic process for the manufacture of pipecolidepsin compounds
    发明人:PELAY GIMENO MARTA; GARCÃ?A-RAMOS YESICA; TULLA PUCHE JUDIT; ALBERICIO PALOMERA FERNANDO; MARTÃ?N LÓPEZ M JES S
    权利人:PHARMA MAR SA
    摘要:(I) wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , n and Y are as described. The invention provides a process for the synthesis of complex pipecolidepsin and related compounds of formula (I), opening a new field of compounds with useful biological properties. The invention also provides intermediates, useful in the synthesis of compounds of formula (I).

    专利号:US-5175378-A
    优先权日:1990-08-03
    标题 :Synthesis of optically pure forms of ipsdienol
    发明人:BROWN HERBERT C
    权利人:ALDRICH CHEM CO INC
    摘要:An improved process for preparing either optically pure enantiomer of the bark beetle pheromones ipsenol and ipsdienol is provided. The process is also applicable to the condensation of aldehydes of widely varying properties to the corresponding chiral alcohol.

    专利号:US-5175371-A
    优先权日:1990-08-03
    标 题:Synthesis of optically pure forms of ipsenol
    发明人:BROWN HERBERT C
    权利人:ALDRICH CHEM CO INC
    摘要:An improved process for preparing either optically pure enantiomer of the bark beetle pheromones ipsenol and ipsdienol is provided. The process is also applicable to the condensation of aldehydes of widely varying properties to the corresponding chiral alcohol.

    专利号:US-2005043376-A1
    优先权日:1996-12-03
    标题:Synthesis of epothilones, intermediates thereto, analogues and uses thereof
    发明人:DANISHEFSKY SAMUEL J; BERTINATO PETER; SU DAI-SHI; MENG DONGFANG; CHOU TING-CHAO; KAMENECKA TED; SORENSEN ERIK J; BALOG AARON; SAVIN KENNETH A
    摘要:The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献

    参考DOI号:10.1021/ol061339e
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