CAS: 55533-24-9; Boc-Phe(4-Nh2)-Oh

相似化合物

164332-89-2 174132-31-1 943-80-6

上下游产品

CAS号86937-80-6 2-((叔丁氧基羰基)氨基)-... | CAS号33305-77-0 B°C-L-4-硝基苯丙氨酸 | CAS号63-91-2 L-苯丙氨酸 | CAS号949-99-5 4-硝基-L-苯丙氨酸 | CAS号80994-44-1 {[(tert-butoxyc... | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号33173-55-6 B°C-4-叠氮-Phe-OH | CAS号55533-25-0 N-alpha-t-丁基氧基羰... | CAS号114346-31-5 B°C-4-(Fm°C-氨基)... | CAS号33173-55-6 B°C-4-叠氮-Phe-OH | CAS号114117-42-9 B°C-4-(乙酰氨基)-L-苯丙氨酸

📜2-叔丁氧基羰基氨基-3-(4-硝基苯基)-丙酸置于palladium 10% On Activated Carbon 氢气体系中,用 甲醇 作为反应溶剂,20.0 °C,241.32 Kpa 条件下,反应 2.0H,反应生成 Boc-4-氨基-L-苯丙氨酸
参考文献:Inhibitors Of Alpha-4 Beta-1 Mediated Cell Adhesion
标题:Inhibitors Of Alpha-4 Beta-1 Mediated Cell Adhesion

专利信息

专利号:US-2011076718-A1
优先权日:2008-02-27
标题:In vivo incorporation of an unnatural amino acid comprising a 1,2-aminothiol group
发明人：FICHT SIMON; JAHNZ MICHAEL; GRUNEWALD JAN; SCHILLER STEFAN; SCHULTZ PETER G
权利人:SCRIPPS RESEARCH INST
摘要:The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate unnatural amino acids that comprise a 1,2 aminothiol group into polypeptides. The invention provides translation systems in which polypeptides comprising unnatural amino acids that comprise a 1,2 aminothiol group can be produced. The invention also provides methods for producing polypeptides containing unnatural amino acids that comprise a 1,2 aminothiol group. Also provided by the invention are compositions comprising orthogonal aminoacyl-tRNA synthetases that preferentially aminoacylate a cognate orthogonal tRNA with unnatural amino acids that comprise a 1,2 aminothiol group. The invention provides methods for the synthesis of the unnatural amino acid 2-amino-3-(4-(2-amino-3-mercaptopropan-amido)phenyl)-propanoic acid.

专利号:US-5710249-A
优先权日:1989-10-30
标题 :Amino acids and processes for making peptides using same
发明人：HOEGER CARL A; RIVIER JEAN E F; PORTER JOHN S
权利人:SALK INST FOR BIOLOGICAL STUDI
摘要:Methods of making unnatural amino acids are provided which unnatural amino acids can be incorporated into peptides which either inhibit or promote the secretion of gonadotropins by the pituitary gland and inhibit the release of steroids by the gonads. These unnatural amino acids are useful in the synthesis of peptides and have the formula (a): where W is (CH2) or n is an integer from 1 to 6; j=1, 2 or 3, and preferably, Y is N-CN, X is NH and R2 is alkyl, modified alkyl, alkenyl, alkynyl, aryl or methyl pyridyl. Disclosed are peptides that are analogs of the decapeptide GnRH wherein there is at least one residue of an unnatural amino acid in the 3-, 5-, 6- and/or 8-positions.

专利号:NZ-267921-A
优先权日:1993-06-17
标 题:Phenylalanine derivatives prepared by nitration of phenylalanine, followed by reduction and reaction with diphenylcyanocarbonimidate; peptide synthesis